Next Article in Journal
Exocrine Pancreatic Function in Girls with Anorexia Nervosa
Next Article in Special Issue
A Systems Approach Dissociates Fructose-Induced Liver Triglyceride from Hypertriglyceridemia and Hyperinsulinemia in Male Mice
Previous Article in Journal
Self-Reported Restrictive Eating, Eating Disorders, Menstrual Dysfunction, and Injuries in Athletes Competing at Different Levels and Sports
 
 
Review

Maternal Fructose Diet-Induced Developmental Programming

1
Department of Pediatrics, Division of Endocrinology and Diabetes, Washington University School of Medicine, St. Louis, MO 63110, USA
2
Department of Pediatrics, Division of Gastroenterology, Washington University School of Medicine, St. Louis, MO 63110, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Luisa Cigliano
Nutrients 2021, 13(9), 3278; https://doi.org/10.3390/nu13093278
Received: 16 August 2021 / Revised: 12 September 2021 / Accepted: 17 September 2021 / Published: 20 September 2021
(This article belongs to the Special Issue Fructose Metabolism and Metabolic Health Effects)
Developmental programming of chronic diseases by perinatal exposures/events is the basic tenet of the developmental origins hypothesis of adult disease (DOHaD). With consumption of fructose becoming more common in the diet, the effect of fructose exposure during pregnancy and lactation is of increasing relevance. Human studies have identified a clear effect of fructose consumption on maternal health, but little is known of the direct or indirect effects on offspring. Animal models have been utilized to evaluate this concept and an association between maternal fructose and offspring chronic disease, including hypertension and metabolic syndrome. This review will address the mechanisms of developmental programming by maternal fructose and potential options for intervention. View Full-Text
Keywords: fructose; metabolism; obesity; hypertension; metabolic syndrome; diabetes; uric acid; developmental origins hypothesis of adult disease (DOHaD) fructose; metabolism; obesity; hypertension; metabolic syndrome; diabetes; uric acid; developmental origins hypothesis of adult disease (DOHaD)
Show Figures

Figure 1

MDPI and ACS Style

Thompson, M.D.; DeBosch, B.J. Maternal Fructose Diet-Induced Developmental Programming. Nutrients 2021, 13, 3278. https://doi.org/10.3390/nu13093278

AMA Style

Thompson MD, DeBosch BJ. Maternal Fructose Diet-Induced Developmental Programming. Nutrients. 2021; 13(9):3278. https://doi.org/10.3390/nu13093278

Chicago/Turabian Style

Thompson, Michael D., and Brian J. DeBosch. 2021. "Maternal Fructose Diet-Induced Developmental Programming" Nutrients 13, no. 9: 3278. https://doi.org/10.3390/nu13093278

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop