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Effect of Polyphenols Intake on Obesity-Induced Maternal Programming

Post Graduate Program in Health Science, Universidade São Francisco (USF), Bragança Paulista 12916-900, SP, Brazil
Lymphoma Translational Group, Josep Carreras Leukemia Research Institute (IJC), 08916 Badalona, Spain
Authors to whom correspondence should be addressed.
Academic Editors: Silvia Di Giacomo and Antonella Di Sotto
Nutrients 2021, 13(7), 2390;
Received: 25 May 2021 / Revised: 30 June 2021 / Accepted: 3 July 2021 / Published: 13 July 2021
Excess caloric intake and body fat accumulation lead to obesity, a complex chronic disease that represents a significant public health problem due to the health-related risk factors. There is growing evidence showing that maternal obesity can program the offspring, which influences neonatal phenotype and predispose offspring to metabolic disorders such as obesity. This increased risk may also be epigenetically transmitted across generations. Thus, there is an imperative need to find effective reprogramming approaches in order to resume normal fetal development. Polyphenols are bioactive compounds found in vegetables and fruits that exert its anti-obesity effect through its powerful anti-oxidant and anti-inflammatory activities. Polyphenol supplementation has been proven to counteract the prejudicial effects of maternal obesity programming on progeny. Indeed, some polyphenols can cross the placenta and protect the fetal predisposition against obesity. The present review summarizes the effects of dietary polyphenols on obesity-induced maternal reprogramming as an offspring anti-obesity approach. View Full-Text
Keywords: bioactive compounds; nutraceutical; maternal obesity; adipose tissue; metabolic disorders bioactive compounds; nutraceutical; maternal obesity; adipose tissue; metabolic disorders
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MDPI and ACS Style

Fortunato, I.M.; dos Santos, T.W.; Ferraz, L.F.C.; Santos, J.C.; Ribeiro, M.L. Effect of Polyphenols Intake on Obesity-Induced Maternal Programming. Nutrients 2021, 13, 2390.

AMA Style

Fortunato IM, dos Santos TW, Ferraz LFC, Santos JC, Ribeiro ML. Effect of Polyphenols Intake on Obesity-Induced Maternal Programming. Nutrients. 2021; 13(7):2390.

Chicago/Turabian Style

Fortunato, Isabela Monique, Tanila Wood dos Santos, Lucio Fábio Caldas Ferraz, Juliana Carvalho Santos, and Marcelo Lima Ribeiro. 2021. "Effect of Polyphenols Intake on Obesity-Induced Maternal Programming" Nutrients 13, no. 7: 2390.

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