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Nutrients
Volume 13
Issue 5
10.3390/nu13051402
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Article

DeltaF508 CFTR Hetero- and Homozygous Paediatric Patients with Cystic Fibrosis Do Not Differ with Regard to Nutritional Status

by
Aleksandra Mędza
1,*,
Katarzyna Kaźmierska
2,
Bartosz Wielgomas
3,
Lucyna Konieczna
4,
Ilona Olędzka
4,
Agnieszka Szlagatys-Sidorkiewicz
5 and
Katarzyna Sznurkowska
5
1
Department of Pediatrics, Pediatric Gastroenterology, Allergology and Nutrition, Copernicus Hospital, Nowe Ogrody 1-6, 80-803 Gdańsk, Poland
2
Medical Clinic “Na Wzgórzu”, Jaworzniaków 37, 80-180 Gdańsk, Poland
3
Department of Toxicology, Faculty of Pharmacy, Medical University of Gdańsk, Al. J. Gen. Hallera 107, 80-416 Gdańsk, Poland
4
Department of Pharmaceutical Chemistry, Medical University of Gdansk, Al. Gen. J. Hallera 107, 80-416 Gdansk, Poland
5
Department of Pediatrics, Pediatric Gastroenterology, Allergology and Nutrition, Medical University of Gdańsk, Nowe Ogrody 1-6, 80-803 Gdańsk, Poland
*
Author to whom correspondence should be addressed.
Nutrients 2021, 13(5), 1402; https://doi.org/10.3390/nu13051402
Submission received: 14 February 2021 / Revised: 3 April 2021 / Accepted: 19 April 2021 / Published: 21 April 2021
(This article belongs to the Special Issue Nutrition in Cystic Fibrosis)
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Abstract

The purpose of this study was to compare the nutritional status between deltaF508 CFTR hetero- and homozygous paediatric patients with cystic fibrosis. We assessed the percentage profiles of fatty acids measured in erythrocyte membranes and the serum levels of vitamins A, D3, E and K1 in the studied groups. We also measured the weights and heights and calculated the body mass indexes (BMIs). The studied groups consisted of 34 heterozygous and 30 homozygous patients. No statistically significant differences were found in the serum vitamins or erythrocyte membrane fatty acid profiles between the hetero- and homozygous patient groups, except for heptadecanoic acid (p = 0.038). The mean percentiles of height, weight and BMI did not differ significantly between the two groups. The homozygous and heterozygous paediatric patients with cystic fibrosis were similar in terms of their nutritional statuses.
Keywords: cystic fibrosis; nutritional status; fatty acids; vitamins; body composition cystic fibrosis; nutritional status; fatty acids; vitamins; body composition

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MDPI and ACS Style

Mędza, A.; Kaźmierska, K.; Wielgomas, B.; Konieczna, L.; Olędzka, I.; Szlagatys-Sidorkiewicz, A.; Sznurkowska, K. DeltaF508 CFTR Hetero- and Homozygous Paediatric Patients with Cystic Fibrosis Do Not Differ with Regard to Nutritional Status. Nutrients 2021, 13, 1402. https://doi.org/10.3390/nu13051402

AMA Style

Mędza A, Kaźmierska K, Wielgomas B, Konieczna L, Olędzka I, Szlagatys-Sidorkiewicz A, Sznurkowska K. DeltaF508 CFTR Hetero- and Homozygous Paediatric Patients with Cystic Fibrosis Do Not Differ with Regard to Nutritional Status. Nutrients. 2021; 13(5):1402. https://doi.org/10.3390/nu13051402

Chicago/Turabian Style

Mędza, Aleksandra, Katarzyna Kaźmierska, Bartosz Wielgomas, Lucyna Konieczna, Ilona Olędzka, Agnieszka Szlagatys-Sidorkiewicz, and Katarzyna Sznurkowska. 2021. "DeltaF508 CFTR Hetero- and Homozygous Paediatric Patients with Cystic Fibrosis Do Not Differ with Regard to Nutritional Status" Nutrients 13, no. 5: 1402. https://doi.org/10.3390/nu13051402

APA Style

Mędza, A., Kaźmierska, K., Wielgomas, B., Konieczna, L., Olędzka, I., Szlagatys-Sidorkiewicz, A., & Sznurkowska, K. (2021). DeltaF508 CFTR Hetero- and Homozygous Paediatric Patients with Cystic Fibrosis Do Not Differ with Regard to Nutritional Status. Nutrients, 13(5), 1402. https://doi.org/10.3390/nu13051402

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