A Vicious Cycle of Osteosarcopenia in Inflammatory Bowel Diseases—Aetiology, Clinical Implications and Therapeutic Perspectives

Skrzypczak, Dorota; Ratajczak, Alicja Ewa; Szymczak-Tomczak, Aleksandra; Dobrowolska, Agnieszka; Eder, Piotr; Krela-Kaźmierczak, Iwona

doi:10.3390/nu13020293

Open AccessReview

A Vicious Cycle of Osteosarcopenia in Inflammatory Bowel Diseases—Aetiology, Clinical Implications and Therapeutic Perspectives

by

Dorota Skrzypczak

^*,

Alicja Ewa Ratajczak

,

Aleksandra Szymczak-Tomczak

,

Agnieszka Dobrowolska

,

Piotr Eder

and

Iwona Krela-Kaźmierczak

^*

Department of Gastroenterology, Dietetics and Internal Diseases, Poznan University of Medical Sciences, 49 Przybyszewskiego Street, 60-355 Poznan, Poland

^*

Authors to whom correspondence should be addressed.

Nutrients 2021, 13(2), 293; https://doi.org/10.3390/nu13020293

Submission received: 16 December 2020 / Revised: 8 January 2021 / Accepted: 18 January 2021 / Published: 20 January 2021

(This article belongs to the Section Nutrition and Metabolism)

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Abstract

Sarcopenia is a disorder characterized by a loss of muscle mass which leads to the reduction of muscle strength and a decrease in the quality and quantity of muscle. It was previously thought that sarcopenia was specific to ageing. However, sarcopenia may affect patients suffering from chronic diseases throughout their entire lives. A decreased mass of muscle and bone is common among patients with inflammatory bowel disease (IBD). Since sarcopenia and osteoporosis are closely linked, they should be diagnosed as mutual consequences of IBD. Additionally, multidirectional treatment of sarcopenia and osteoporosis including nutrition, physical activity, and pharmacotherapy should include both disorders, referred to as osteosarcopenia.

Keywords: sarcopenia; IBD; Crohn’s disease; ulcerative colitis; malnutrition; low muscle mass; low muscle strength; nutritional therapy

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MDPI and ACS Style

Skrzypczak, D.; Ratajczak, A.E.; Szymczak-Tomczak, A.; Dobrowolska, A.; Eder, P.; Krela-Kaźmierczak, I. A Vicious Cycle of Osteosarcopenia in Inflammatory Bowel Diseases—Aetiology, Clinical Implications and Therapeutic Perspectives. Nutrients 2021, 13, 293. https://doi.org/10.3390/nu13020293

AMA Style

Skrzypczak D, Ratajczak AE, Szymczak-Tomczak A, Dobrowolska A, Eder P, Krela-Kaźmierczak I. A Vicious Cycle of Osteosarcopenia in Inflammatory Bowel Diseases—Aetiology, Clinical Implications and Therapeutic Perspectives. Nutrients. 2021; 13(2):293. https://doi.org/10.3390/nu13020293

Chicago/Turabian Style

Skrzypczak, Dorota, Alicja Ewa Ratajczak, Aleksandra Szymczak-Tomczak, Agnieszka Dobrowolska, Piotr Eder, and Iwona Krela-Kaźmierczak. 2021. "A Vicious Cycle of Osteosarcopenia in Inflammatory Bowel Diseases—Aetiology, Clinical Implications and Therapeutic Perspectives" Nutrients 13, no. 2: 293. https://doi.org/10.3390/nu13020293

APA Style

Skrzypczak, D., Ratajczak, A. E., Szymczak-Tomczak, A., Dobrowolska, A., Eder, P., & Krela-Kaźmierczak, I. (2021). A Vicious Cycle of Osteosarcopenia in Inflammatory Bowel Diseases—Aetiology, Clinical Implications and Therapeutic Perspectives. Nutrients, 13(2), 293. https://doi.org/10.3390/nu13020293

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A Vicious Cycle of Osteosarcopenia in Inflammatory Bowel Diseases—Aetiology, Clinical Implications and Therapeutic Perspectives

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