Associations of Habitual Mineral Intake with New-Onset Prediabetes/Diabetes after Acute Pancreatitis
Abstract
:1. Introduction
2. Methods
2.1. Study Design
2.2. Study Population
2.3. Study Groups
2.4. Ascertainment of Mineral Intake
2.5. Laboratory Assays
2.6. Covariates
2.7. Statistical Analysis
3. Results
3.1. Characteristics of the Study Cohort
3.2. Associations between Habitual Mineral Intake and Diabetes Types
3.3. Associations between Habitual Mineral Intake and Markers of Glucose Metabolism in the Study Groups
3.4. Associations between Habitual Mineral Intake and Insulin Traits in the Study Groups
4. Discussion
4.1. Manganese Intake and Glucose Metabolism
4.2. Iron Intake and Glucose Metabolism
4.3. Iodine and Selenium Intakes and Glucose Metabolism
4.4. Limitations
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Characteristic | Total | NODAP | T2DM | NAP | p * |
---|---|---|---|---|---|
(n = 106) | (n = 37) | (n = 37) | (n = 32) | ||
Age | 56.1 (14.5) | 58.9 (14.4) | 57.2(15.0) | 51.6(13.3) | 0.094 |
Sex | 0.031 | ||||
Men | 69 (65.1) | 26 (70.3) | 28 (75.7) | 15 (46.9) | |
Women | 37 (34.9) | 11 (29.7) | 9 (24.3) | 17 (53.1) | |
Daily energy intake (kcal) | 1686 (609) | 1776 (692) | 1728 (534) | 1534 (574) | 0.226 |
V/S fat volume ratio | 0.77 (0.43) | 0.81 (0.40) | 0.87 (0.46) | 0.61 (0.40) | 0.035 |
Alcohol intake (g/day) | 11.1 (17.9) | 13.4 (21.9) | 8.7 (13.1) | 11.1 (17.7) | 0.527 |
Smoking status | 0.052 | ||||
Never | 47 (44) | 11 30) | 21 (57) | 15 (47) | |
Former | 35 (33) | 16 (4) | 11 (30) | 8 (25) | |
Light (<20 a/d) | 8 (8) | 3 (8) | 2 (5) | 3 (9) | |
Moderate (20–39 a/d) | 15 (14) | 7 (19) | 2 (5) | 6 (19) | |
Heavy (>39 a/d) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |
Aetiology of AP | 0.563 | ||||
Biliary | 40 (38) | 14 (38) | 14 (38) | 12 (38) | |
Alcohol-related | 21 (20) | 12 (32) | 5 (14) | 4 (13) | |
Other | 45 (43) | 11 (30) | 18 (49) | 16 (50) | |
Number of AP episodes | 1.9 (2.8) | 2.3 (3.8) | 1.4 (1.0) | 1.8 (2.8) | 0.434 |
Cholecystectomy | 0.538 | ||||
No | 66 (62) | 24 (65) | 25 (68) | 17 (53) | |
Yes | 39 (37) | 13 (35) | 12 (32) | 14 (44) | |
Use of anti-diabetic medications | <0.001 | ||||
None | 92 (87) | 37 (100) | 23 (62) | 32 (100) | |
Oral medication | 8 (8) | 0 (0) | 8 (22) | 0 (0) | |
Insulin | 6 (6) | 0 (0) | 6 (16) | 0 (0) | |
HbA1c (mmol/mol) | 40.61 (10.82) | 39.05 (4.80) | 47.19 (15.23) | 34.61 (2.55) | <0.001 |
Fasting plasma glucose (mmol/L) | 5.86 (1.74) | 5.86 (0.92) | 6.61 (2.55) | 4.96 (0.34) | <0.001 |
Fasting insulin (mU/L) | 16.68 (36.01) | 12.98 (9.96) | 24.62 (59.95) | 12.15 (10.27) | 0.277 |
HOMA-S (%) | 0.88 (0.74) | 1.02 (1.06) | 0.72 (0.44) | 0.90 (0.49) | 0.228 |
HOMA-β (%) | 106.97 (56.87) | 95.74 (45.63) | 103.24 (57.12) | 125.07 (65.87) | 0.098 |
Mineral | Model | T2DM | NODAP | ||||||
---|---|---|---|---|---|---|---|---|---|
β | p | 95% CI | β | p | 95% CI | ||||
Lower | Upper | Lower | Upper | ||||||
Calcium (mg) | 1 | 0.009 | 0.821 | −0.070 | 0.089 | −0.023 | 0.565 | −0.102 | 0.056 |
2 | −0.020 | 0.537 | −0.082 | 0.043 | −0.059 | 0.063 | −0.120 | 0.003 | |
3 | −0.018 | 0.581 | −0.080 | 0.045 | −0.058 | 0.064 | −0.120 | 0.003 | |
4 | −0.022 | 0.506 | −0.089 | 0.044 | −0.057 | 0.073 | −0.120 | 0.005 | |
5 | −0.010 | 0.797 | −0.087 | 0.067 | −0.056 | 0.091 | −0.121 | 0.009 | |
Chloride (mg) | 1 | 0.047 | 0.326 | −0.047 | 0.141 | 0.040 | 0.396 | −0.053 | 0.133 |
2 | 0.000 | 0.996 | −0.057 | 0.057 | −0.020 | 0.471 | −0.077 | 0.036 | |
3 | 0.003 | 0.926 | −0.054 | 0.060 | −0.020 | 0.471 | −0.077 | 0.036 | |
4 | 0.002 | 0.939 | −0.057 | 0.061 | −0.023 | 0.417 | −0.079 | 0.033 | |
5 | 0.024 | 0.492 | −0.045 | 0.093 | −0.025 | 0.394 | −0.084 | 0.033 | |
Copper (mg) | 1 | 0.123 | 0.012 | 0.027 | 0.219 | 0.090 | 0.064 | −0.005 | 0.185 |
2 | 0.073 | 0.039 | 0.004 | 0.141 | 0.026 | 0.445 | −0.042 | 0.094 | |
3 | 0.078 | 0.026 | 0.010 | 0.146 | 0.026 | 0.436 | −0.041 | 0.093 | |
4 | 0.072 | 0.049 | 0.000 | 0.144 | 0.026 | 0.458 | −0.043 | 0.094 | |
5 | 0.061 | 0.147 | −0.022 | 0.145 | 0.019 | 0.592 | −0.052 | 0.090 | |
Iodine (μg) | 1 | 0.046 | 0.259 | −0.034 | 0.126 | 0.017 | 0.675 | −0.063 | 0.097 |
2 | 0.030 | 0.402 | −0.040 | 0.099 | −0.007 | 0.846 | −0.076 | 0.062 | |
3 | 0.037 | 0.269 | −0.029 | 0.104 | −0.007 | 0.843 | −0.073 | 0.059 | |
4 | 0.015 | 0.666 | −0.054 | 0.084 | −0.009 | 0.787 | −0.074 | 0.056 | |
5 | 0.010 | 0.811 | −0.071 | 0.091 | 0.000 | 0.990 | −0.069 | 0.068 | |
Iron (mg) | 1 | 0.012 | 0.785 | −0.076 | 0.101 | −0.002 | 0.963 | −0.090 | 0.086 |
2 | −0.037 | 0.205 | −0.096 | 0.021 | −0.064 | 0.029 | −0.122 | −0.007 | |
3 | −0.036 | 0.220 | −0.095 | 0.022 | −0.064 | 0.030 | −0.122 | −0.006 | |
4 | −0.034 | 0.272 | −0.094 | 0.027 | −0.061 | 0.036 | −0.119 | −0.004 | |
5 | −0.034 | 0.342 | −0.104 | 0.036 | −0.076 | 0.013 | −0.135 | −0.016 | |
Magnesium (mg) | 1 | 0.025 | 0.513 | −0.051 | 0.100 | 0.034 | 0.371 | −0.041 | 0.109 |
2 | −0.013 | 0.582 | −0.062 | 0.035 | −0.013 | 0.581 | −0.061 | 0.035 | |
3 | −0.011 | 0.665 | −0.059 | 0.038 | −0.013 | 0.579 | −0.061 | 0.034 | |
4 | −0.015 | 0.559 | −0.066 | 0.036 | −0.013 | 0.600 | −0.061 | 0.035 | |
5 | −0.016 | 0.589 | −0.076 | 0.043 | −0.017 | 0.516 | −0.067 | 0.034 | |
Manganese (mg) | 1 | 0.022 | 0.687 | −0.085 | 0.128 | 0.028 | 0.600 | −0.078 | 0.134 |
2 | −0.006 | 0.878 | −0.089 | 0.076 | −0.017 | 0.687 | −0.098 | 0.065 | |
3 | −0.003 | 0.942 | −0.085 | 0.079 | −0.017 | 0.688 | −0.098 | 0.065 | |
4 | −0.021 | 0.633 | −0.107 | 0.065 | −0.020 | 0.634 | −0.101 | 0.062 | |
5 | −0.049 | 0.343 | −0.150 | 0.053 | −0.035 | 0.418 | −0.121 | 0.051 | |
Nitrogen (g) | 1 | 0.010 | 0.784 | −0.060 | 0.079 | −0.025 | 0.474 | −0.094 | 0.044 |
2 | −0.023 | 0.299 | −0.066 | 0.021 | −0.066 | 0.003 | −0.109 | −0.023 | |
3 | −0.021 | 0.346 | −0.064 | 0.023 | −0.066 | 0.003 | −0.109 | −0.023 | |
4 | −0.042 | 0.055 | −0.086 | 0.001 | −0.065 | 0.002 | −0.106 | −0.024 | |
5 | −0.033 | 0.205 | −0.084 | 0.018 | −0.066 | 0.003 | −0.110 | −0.023 | |
Phosphorous (mg) | 1 | 0.017 | 0.610 | −0.048 | 0.081 | −0.005 | 0.880 | −0.069 | 0.059 |
2 | −0.017 | 0.291 | −0.050 | 0.015 | −0.046 | 0.005 | −0.078 | −0.014 | |
3 | −0.015 | 0.351 | −0.047 | 0.017 | −0.046 | 0.005 | −0.078 | −0.015 | |
4 | −0.026 | 0.124 | −0.059 | 0.007 | −0.045 | 0.005 | −0.077 | −0.014 | |
5 | −0.023 | 0.241 | −0.061 | 0.015 | −0.046 | 0.006 | −0.078 | −0.014 | |
Potassium (mg) | 1 | 0.017 | 0.642 | −0.055 | 0.088 | 0.020 | 0.578 | −0.051 | 0.091 |
2 | −0.019 | 0.449 | −0.069 | 0.031 | −0.025 | 0.318 | −0.074 | 0.024 | |
3 | −0.015 | 0.543 | −0.064 | 0.034 | −0.025 | 0.310 | −0.073 | 0.023 | |
4 | −0.018 | 0.492 | −0.069 | 0.034 | −0.024 | 0.324 | −0.073 | 0.024 | |
5 | −0.020 | 0.510 | −0.080 | 0.040 | −0.026 | 0.322 | −0.076 | 0.025 | |
Selenium (μg) | 1 | 0.058 | 0.202 | −0.032 | 0.147 | 0.035 | 0.439 | −0.054 | 0.123 |
2 | 0.024 | 0.445 | −0.038 | 0.085 | −0.011 | 0.716 | −0.072 | 0.049 | |
3 | −0.011 | 0.713 | −0.071 | 0.049 | −0.011 | 0.713 | −0.071 | 0.049 | |
4 | 0.009 | 0.780 | −0.053 | 0.071 | −0.014 | 0.637 | −0.073 | 0.045 | |
5 | −0.008 | 0.828 | −0.081 | 0.065 | −0.011 | 0.722 | −0.072 | 0.050 | |
Sodium (mg) | 1 | 0.042 | 0.380 | −0.053 | 0.137 | 0.030 | 0.536 | −0.065 | 0.124 |
2 | −0.004 | 0.895 | −0.062 | 0.054 | −0.031 | 0.281 | −0.089 | 0.026 | |
3 | −0.002 | 0.953 | −0.060 | 0.056 | −0.031 | 0.281 | −0.088 | 0.026 | |
4 | −0.005 | 0.875 | −0.065 | 0.055 | 0.009 | 0.780 | −0.053 | 0.071 | |
5 | 0.022 | 0.537 | −0.048 | 0.092 | −0.034 | 0.256 | −0.094 | 0.025 | |
Zinc (mg) | 1 | 0.025 | 0.489 | −0.046 | 0.096 | −0.024 | 0.510 | −0.094 | 0.047 |
2 | −0.017 | 0.459 | −0.063 | 0.029 | −0.071 | 0.002 | −0.116 | −0.026 | |
3 | −0.017 | 0.467 | −0.063 | 0.029 | −0.071 | 0.003 | −0.117 | −0.026 | |
4 | −0.029 | 0.232 | −0.077 | 0.019 | −0.070 | 0.003 | −0.116 | −0.025 | |
5 | −0.017 | 0.527 | −0.071 | 0.037 | −0.078 | 0.001 | −0.124 | −0.033 |
Mineral | Model | NAP | T2DM | NODAP | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
R2 | Unstandardised | p | 95% CI | R2 | Unstandardised | p | 95% CI | R2 | Unstandardised | p | 95% CI | |||||
B | Lower | Upper | B | Lower | Upper | B | Lower | Upper | ||||||||
Calcium (mg) | 1 | 0.003 | 0.695 | 0.772 | −4.164 | 5.554 | 0.028 | −15.434 | 0.368 | −49.861 | 18.994 | 0.055 | 8.423 | 0.164 | −3.610 | 20.456 |
2 | 0.278 | 0.404 | 0.886 | −5.315 | 6.123 | 0.039 | −16.023 | 0.528 | −67.269 | 35.222 | 0.170 | 12.012 | 0.172 | −5.491 | 29.515 | |
3 | 0.280 | 0.452 | 0.875 | −5.397 | 6.301 | 0.081 | −15.410 | 0.541 | −66.347 | 35.528 | 0.190 | 14.180 | 0.124 | −4.111 | 32.470 | |
4 | 0.347 | 1.608 | 0.595 | −4.558 | 7.774 | 0.173 | −22.037 | 0.380 | −72.650 | 28.576 | 0.247 | 13.916 | 0.131 | −4.383 | 32.216 | |
5 | 0.382 | 1.344 | 0.683 | −5.415 | 8.103 | 0.493 | −14.339 | 0.568 | −65.521 | 36.844 | 0.275 | 12.586 | 0.199 | −7.032 | 32.204 | |
Chloride (mg) | 1 | 0.085 | 4.268 | 0.112 | −1.059 | 9.596 | 0.044 | −15.515 | 0.227 | −41.158 | 10.127 | 0.051 | 5.530 | 0.179 | −2.658 | 13.718 |
2 | 0.323 | 5.032 | 0.198 | −2.798 | 12.863 | 0.063 | −24.427 | 0.325 | −74.324 | 25.471 | 0.126 | 4.013 | 0.603 | −11.565 | 19.590 | |
3 | 0.341 | 6.349 | 0.139 | −2.201 | 14.900 | 0.109 | −24.191 | 0.326 | −73.745 | 25.364 | 0.133 | 4.323 | 0.582 | −11.515 | 20.160 | |
4 | 0.382 | 5.548 | 0.217 | −3.484 | 14.580 | 0.222 | −32.960 | 0.184 | −82.570 | 16.650 | 0.191 | 3.785 | 0.633 | −12.267 | 19.837 | |
5 | 0.424 | 5.932 | 0.215 | −3.720 | 15.585 | 0.484 | −11.699 | 0.619 | −59.769 | 36.371 | 0.233 | 3.655 | 0.657 | −13.081 | 20.391 | |
Copper (mg) | 1 | 0.042 | 2.683 | 0.268 | −2.177 | 7.544 | 0.022 | −13.209 | 0.390 | −44.091 | 17.672 | 0.004 | 1.427 | 0.706 | −6.181 | 9.035 |
2 | 0.298 | 3.412 | 0.386 | −4.547 | 11.371 | 0.037 | −8.386 | 0.677 | −49.121 | 32.349 | 0.151 | −6.212 | 0.283 | −17.795 | 5.370 | |
3 | 0.303 | 3.655 | 0.368 | −4.553 | 11.863 | 0.079 | −1.616 | 0.938 | −43.979 | 40.746 | 0.153 | −5.948 | 0.317 | −17.864 | 5.968 | |
4 | 0.343 | 1.698 | 0.701 | −7.325 | 10.722 | 0.170 | −3.533 | 0.864 | −45.511 | 38.445 | 0.208 | −5.829 | 0.356 | −18.551 | 6.893 | |
5 | 0.379 | 1.663 | 0.785 | −10.893 | 14.218 | 0.478 | 0.148 | 0.994 | −37.444 | 37.740 | 0.242 | −4.840 | 0.472 | −18.487 | 8.807 | |
Iodine (μg) | 1 | 0.050 | 3.050 | 0.226 | −1.998 | 8.098 | 0.040 | −21.520 | 0.247 | −58.669 | 15.629 | 0.065 | 7.667 | 0.129 | −2.340 | 17.674 |
2 | 0.298 | 2.446 | 0.394 | −3.351 | 8.244 | 0.052 | −18.384 | 0.425 | −64.815 | 28.047 | 0.185 | 9.758 | 0.116 | −2.534 | 22.049 | |
3 | 0.301 | 2.571 | 0.382 | −3.382 | 8.524 | 0.084 | −10.465 | 0.667 | −59.635 | 38.706 | 0.241 | 14.951 | 0.037 | 0.997 | 28.905 | |
4 | 0.359 | 2.552 | 0.401 | −3.613 | 8.717 | 0.181 | −14.979 | 0.533 | −63.706 | 33.747 | 0.276 | 14.135 | 0.065 | −0.929 | 29.200 | |
5 | 0.390 | 2.185 | 0.520 | −4.771 | 9.140 | 0.498 | −19.879 | 0.350 | −62.977 | 23.219 | 0.354 | 17.763 | 0.032 | 1.601 | 33.926 | |
Iron (mg) | 1 | 0.017 | 1.807 | 0.490 | −3.479 | 7.093 | 0.065 | −22.774 | 0.140 | −53.395 | 7.848 | 0.004 | 1.644 | 0.697 | −6.852 | 10.139 |
2 | 0.278 | −0.183 | 0.959 | −7.449 | 7.082 | 0.099 | −41.281 | 0.146 | −97.747 | 15.184 | 0.153 | −7.510 | 0.264 | −20.979 | 5.958 | |
3 | 0.279 | −0.041 | 0.991 | −7.555 | 7.473 | 0.139 | −39.418 | 0.163 | −95.710 | 16.874 | 0.159 | −7.557 | 0.268 | −21.211 | 6.098 | |
4 | 0.348 | 2.304 | 0.562 | −5.805 | 10.412 | 0.202 | −30.213 | 0.294 | −88.098 | 27.672 | 0.205 | −6.118 | 0.392 | −20.529 | 8.294 | |
5 | 0.392 | 3.614 | 0.477 | −6.799 | 14.027 | 0.478 | −3.564 | 0.893 | −57.916 | 50.788 | 0.242 | −5.279 | 0.478 | −20.352 | 9.794 | |
Magnesium (mg) | 1 | 0.015 | 2.080 | 0.517 | −4.410 | 8.570 | 0.029 | −16.583 | 0.329 | −50.606 | 17.439 | 0.000 | −0.035 | 0.995 | −10.529 | 10.459 |
2 | 0.278 | 0.748 | 0.872 | −8.730 | 10.226 | 0.045 | −17.348 | 0.523 | −72.103 | 37.408 | 0.198 | −15.774 | 0.084 | −33.813 | 2.264 | |
3 | 0.281 | 1.328 | 0.794 | −9.013 | 11.668 | 0.090 | −16.465 | 0.541 | −70.912 | 37.982 | 0.199 | −15.595 | 0.101 | −34.382 | 3.193 | |
4 | 0.342 | 1.603 | 0.752 | −8.779 | 11.985 | 0.182 | −17.570 | 0.509 | −71.398 | 36.259 | 0.241 | −14.792 | 0.152 | −35.363 | 5.779 | |
5 | 0.377 | 0.706 | 0.900 | −10.879 | 12.292 | 0.481 | −9.455 | 0.698 | −59.159 | 40.248 | 0.291 | −15.995 | 0.138 | −37.481 | 5.492 | |
Manganese (mg) | 1 | 0.035 | 2.419 | 0.311 | −2.381 | 7.220 | 0.003 | 3.558 | 0.751 | −19.041 | 26.157 | 0.041 | −4.493 | 0.230 | −11.951 | 2.965 |
2 | 0.322 | 4.217 | 0.201 | −2.395 | 10.829 | 0.070 | 16.181 | 0.274 | −13.505 | 45.866 | 0.338 | −15.097 | 0.003 | −24.555 | −5.638 | |
3 | 0.332 | 4.740 | 0.172 | −2.197 | 11.678 | 0.117 | 16.108 | 0.273 | −13.362 | 45.579 | 0.338 | −15.274 | 0.003 | −25.116 | −5.431 | |
4 | 0.365 | 3.708 | 0.341 | −4.186 | 11.602 | 0.183 | 10.427 | 0.495 | −20.504 | 41.359 | 0.411 | −16.465 | 0.002 | −26.546 | −6.385 | |
5 | 0.399 | 4.551 | 0.392 | −6.300 | 15.401 | 0.490 | 10.357 | 0.469 | −18.745 | 39.458 | 0.455 | −17.147 | 0.003 | −27.829 | −6.464 | |
Nitrogen (g) | 1 | 0.001 | 0.747 | 0.837 | −6.634 | 8.128 | 0.030 | −19.306 | 0.321 | −58.323 | 19.711 | 0.017 | 3.968 | 0.440 | −6.356 | 14.293 |
2 | 0.297 | −4.643 | 0.407 | −15.959 | 6.673 | 0.048 | −24.332 | 0.472 | −92.587 | 43.924 | 0.119 | 0.040 | 0.996 | −17.873 | 17.952 | |
3 | 0.297 | −4.622 | 0.438 | −16.695 | 7.450 | 0.092 | −21.690 | 0.520 | −89.766 | 46.385 | 0.125 | 0.611 | 0.946 | −17.734 | 18.956 | |
4 | 0.366 | −5.911 | 0.327 | −18.122 | 6.301 | 0.169 | −6.075 | 0.872 | −82.534 | 70.384 | 0.184 | −0.280 | 0.977 | −19.817 | 19.257 | |
5 | 0.402 | −6.015 | 0.366 | −19.565 | 7.535 | 0.487 | 21.821 | 0.536 | −50.047 | 93.689 | 0.227 | 0.707 | 0.944 | −19.774 | 21.187 | |
Phosphorous (mg) | 1 | 0.010 | 1.936 | 0.593 | −5.384 | 9.255 | 0.029 | −20.931 | 0.329 | −63.886 | 22.025 | 0.028 | 5.931 | 0.322 | −6.066 | 17.928 |
2 | 0.280 | −1.931 | 0.777 | −15.783 | 11.921 | 0.047 | −28.990 | 0.485 | −112.750 | 54.770 | 0.125 | 7.100 | 0.627 | −22.399 | 36.598 | |
3 | 0.281 | −1.597 | 0.824 | −16.252 | 13.058 | 0.090 | −24.752 | 0.550 | −108.475 | 58.970 | 0.136 | 9.891 | 0.523 | −21.318 | 41.100 | |
4 | 0.341 | −2.105 | 0.776 | −17.217 | 13.006 | 0.178 | −23.107 | 0.582 | −108.193 | 61.980 | 0.205 | 14.626 | 0.389 | −19.608 | 48.860 | |
5 | 0.381 | −2.991 | 0.706 | −19.313 | 13.331 | 0.478 | −5.990 | 0.885 | −90.846 | 78.867 | 0.244 | 13.957 | 0.448 | −23.277 | 51.190 | |
Potassium (mg) | 1 | 0.007 | 1.337 | 0.662 | −4.851 | 7.526 | 0.036 | −19.541 | 0.274 | −55.273 | 16.190 | 0.001 | 1.188 | 0.845 | −11.066 | 13.442 |
2 | 0.278 | 0.318 | 0.935 | −7.579 | 8.216 | 0.054 | −24.484 | 0.404 | −83.561 | 34.593 | 0.172 | −14.573 | 0.160 | −35.223 | 6.077 | |
3 | 0.280 | 0.700 | 0.867 | −7.806 | 9.207 | 0.093 | −19.581 | 0.507 | −79.212 | 40.049 | 0.172 | −14.359 | 0.190 | −36.204 | 7.486 | |
4 | 0.342 | 1.503 | 0.721 | −7.086 | 10.093 | 0.187 | −22.375 | 0.442 | −81.154 | 36.405 | 0.212 | −11.737 | 0.321 | −35.497 | 12.022 | |
5 | 0.378 | 0.938 | 0.838 | −8.489 | 10.366 | 0.495 | −22.591 | 0.387 | −75.593 | 30.410 | 0.261 | −13.299 | 0.286 | −38.402 | 11.804 | |
Selenium (μg) | 1 | 0.040 | 2.931 | 0.282 | −2.541 | 8.404 | 0.001 | −3.726 | 0.836 | −40.123 | 32.672 | 0.028 | 3.654 | 0.321 | −3.718 | 11.025 |
2 | 0.283 | 1.851 | 0.674 | −7.101 | 10.803 | 0.042 | 15.057 | 0.575 | −39.189 | 69.303 | 0.123 | 2.239 | 0.697 | −9.372 | 13.850 | |
3 | 0.285 | 1.978 | 0.661 | −7.198 | 11.155 | 0.117 | 31.274 | 0.272 | −25.844 | 88.391 | 0.130 | 2.706 | 0.646 | −9.201 | 14.612 | |
4 | 0.343 | 1.688 | 0.710 | −7.586 | 10.963 | 0.215 | 39.157 | 0.218 | −24.592 | 102.907 | 0.186 | 1.519 | 0.799 | −10.596 | 13.633 | |
5 | 0.379 | 1.311 | 0.784 | −8.516 | 11.139 | 0.487 | 17.826 | 0.540 | −41.505 | 77.158 | 0.237 | 3.642 | 0.569 | −9.322 | 16.607 | |
Sodium (mg) | 1 | 0.088 | 4.275 | 0.104 | −0.940 | 9.490 | 0.040 | −14.905 | 0.248 | −40.714 | 10.904 | 0.052 | 5.413 | 0.175 | −2.519 | 13.345 |
2 | 0.334 | 5.458 | 0.150 | −2.114 | 13.030 | 0.056 | −21.295 | 0.389 | −71.052 | 28.463 | 0.128 | 4.165 | 0.575 | −10.800 | 19.130 | |
3 | 0.352 | 6.607 | 0.107 | −1.542 | 14.757 | 0.102 | −21.094 | 0.390 | −70.514 | 28.327 | 0.134 | 4.312 | 0.567 | −10.871 | 19.495 | |
4 | 0.390 | 5.738 | 0.179 | −2.828 | 14.305 | 0.216 | −31.273 | 0.214 | −81.738 | 19.192 | 0.191 | 3.797 | 0.619 | −11.648 | 19.243 | |
5 | 0.438 | 6.639 | 0.153 | −2.688 | 15.966 | 0.480 | −7.151 | 0.770 | −57.207 | 42.906 | 0.235 | 4.181 | 0.597 | −11.894 | 20.256 | |
Zinc (mg) | 1 | 0.000 | 0.059 | 0.986 | −6.747 | 6.865 | 0.033 | −19.770 | 0.295 | −57.549 | 18.010 | 0.026 | 4.984 | 0.343 | −5.549 | 15.517 |
2 | 0.327 | −6.886 | 0.179 | −17.132 | 3.360 | 0.062 | −29.825 | 0.329 | −91.235 | 31.585 | 0.120 | 2.044 | 0.817 | −15.812 | 19.899 | |
3 | 0.327 | −7.089 | 0.193 | −18.004 | 3.826 | 0.124 | −36.619 | 0.231 | −97.872 | 24.634 | 0.126 | 2.199 | 0.806 | −15.918 | 20.315 | |
4 | 0.401 | −8.146 | 0.134 | −19.009 | 2.716 | 0.188 | −25.215 | 0.431 | −89.980 | 39.550 | 0.185 | 1.313 | 0.886 | −17.316 | 19.943 | |
5 | 0.464 | −12.169 | 0.085 | −26.193 | 1.856 | 0.480 | 8.802 | 0.779 | −55.273 | 72.876 | 0.227 | 0.970 | 0.919 | −18.434 | 20.375 |
Mineral | Model | NAP | T2DM | NODAP | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
R2 | Unstandardised | p | 95% CI | R2 | Unstandardised | p | 95% CI | R2 | Unstandardised | p | 95% CI | |||||
B | Lower | Upper | B | Lower | Upper | B | Lower | Upper | ||||||||
Calcium (mg) | 1 | 0.004 | 0.097 | 0.753 | −0.527 | 0.720 | 0.021 | −2.219 | 0.404 | −7.561 | 3.124 | 0.090 | 2.072 | 0.071 | −0.191 | 4.334 |
2 | 0.151 | 0.149 | 0.703 | −0.648 | 0.947 | 0.049 | −2.695 | 0.492 | −10.614 | 5.225 | 0.228 | 1.495 | 0.354 | −1.740 | 4.730 | |
3 | 0.222 | 0.185 | 0.630 | −0.598 | 0.967 | 0.088 | −2.608 | 0.505 | −10.511 | 5.296 | 0.234 | 1.722 | 0.311 | −1.688 | 5.131 | |
4 | 0.225 | 0.192 | 0.651 | −0.675 | 1.058 | 0.283 | −3.788 | 0.302 | −11.177 | 3.601 | 0.268 | 1.659 | 0.335 | −1.799 | 5.117 | |
5 | 0.232 | 0.163 | 0.730 | −0.814 | 1.140 | 0.545 | −3.188 | 0.386 | −10.646 | 4.271 | 0.303 | 1.746 | 0.339 | −1.941 | 5.432 | |
Chloride (mg) | 1 | 0.025 | 0.302 | 0.399 | −0.421 | 1.025 | 0.052 | −2.620 | 0.187 | −6.575 | 1.335 | 0.068 | 1.224 | 0.119 | −0.331 | 2.780 |
2 | 0.164 | 0.410 | 0.472 | −0.745 | 1.565 | 0.091 | −5.102 | 0.181 | −12.716 | 2.513 | 0.209 | −0.488 | 0.728 | −3.329 | 2.352 | |
3 | 0.270 | 0.771 | 0.188 | −0.402 | 1.945 | 0.129 | −5.068 | 0.182 | −12.658 | 2.521 | 0.210 | −0.467 | 0.745 | −3.364 | 2.431 | |
4 | 0.280 | 0.854 | 0.180 | −0.424 | 2.132 | 0.340 | −6.499 | 0.070 | −13.578 | 0.579 | 0.247 | −0.497 | 0.735 | −3.465 | 2.471 | |
5 | 0.295 | 0.905 | 0.192 | −0.497 | 2.308 | 0.553 | −3.676 | 0.284 | −10.607 | 3.256 | 0.283 | −0.630 | 0.680 | −3.732 | 2.471 | |
Copper (mg) | 1 | 0.022 | −0.242 | 0.439 | −0.875 | 0.390 | 0.032 | −2.426 | 0.308 | −7.187 | 2.336 | 0.025 | 0.677 | 0.347 | −0.766 | 2.119 |
2 | 0.277 | −1.073 | 0.044 | −2.113 | −0.033 | 0.050 | −2.194 | 0.480 | −8.463 | 4.074 | 0.249 | −1.382 | 0.187 | −3.469 | 0.706 | |
3 | 0.320 | −0.977 | 0.065 | −2.021 | 0.066 | 0.079 | −1.322 | 0.683 | −7.884 | 5.241 | 0.249 | −1.380 | 0.200 | −3.530 | 0.770 | |
4 | 0.329 | −1.084 | 0.069 | −2.262 | 0.093 | 0.264 | −1.868 | 0.537 | −7.989 | 4.254 | 0.292 | −1.577 | 0.173 | −3.883 | 0.730 | |
5 | 0.416 | −1.901 | 0.023 | −3.508 | −0.294 | 0.535 | −1.471 | 0.585 | −6.964 | 4.023 | 0.333 | −1.754 | 0.154 | −4.208 | 0.699 | |
Iodine (μg) | 1 | 0.008 | 0.154 | 0.637 | −0.508 | 0.816 | 0.046 | −3.572 | 0.214 | −9.309 | 2.165 | 0.058 | 1.392 | 0.151 | −0.533 | 3.316 |
2 | 0.147 | 0.073 | 0.856 | −0.749 | 0.895 | 0.061 | −3.252 | 0.361 | −10.412 | 3.909 | 0.219 | 0.838 | 0.464 | −1.468 | 3.144 | |
3 | 0.219 | 0.147 | 0.711 | −0.664 | 0.958 | 0.084 | −2.203 | 0.559 | −9.821 | 5.415 | 0.231 | 1.288 | 0.337 | −1.405 | 3.980 | |
4 | 0.223 | 0.176 | 0.681 | −0.701 | 1.054 | 0.274 | −3.022 | 0.391 | −10.129 | 4.084 | 0.254 | 0.919 | 0.526 | −2.011 | 3.850 | |
5 | 0.230 | 0.118 | 0.811 | −0.902 | 1.138 | 0.562 | −3.979 | 0.200 | −10.211 | 2.254 | 0.280 | 0.392 | 0.807 | −2.878 | 3.663 | |
Iron (mg) | 1 | 0.004 | −0.110 | 0.745 | −0.793 | 0.574 | 0.070 | −3.652 | 0.126 | −8.384 | 1.079 | 0.031 | 0.843 | 0.294 | −0.763 | 2.448 |
2 | 0.186 | −0.536 | 0.276 | −1.527 | 0.456 | 0.130 | −7.646 | 0.079 | −16.241 | 0.950 | 0.232 | −1.264 | 0.302 | −3.721 | 1.193 | |
3 | 0.240 | −0.430 | 0.381 | −1.425 | 0.565 | 0.162 | −7.387 | 0.090 | −15.990 | 1.216 | 0.234 | −1.268 | 0.308 | −3.766 | 1.229 | |
4 | 0.254 | −0.564 | 0.307 | −1.683 | 0.555 | 0.296 | −5.258 | 0.211 | −13.683 | 3.166 | 0.265 | −1.186 | 0.369 | −3.842 | 1.470 | |
5 | 0.280 | −0.830 | 0.254 | −2.308 | 0.647 | 0.533 | −1.636 | 0.675 | −9.604 | 6.332 | 0.300 | −1.215 | 0.377 | −3.992 | 1.562 | |
Magnesium (mg) | 1 | 0.060 | −0.533 | 0.193 | −1.350 | 0.285 | 0.031 | −2.638 | 0.316 | −7.904 | 2.629 | 0.032 | 1.051 | 0.288 | −0.927 | 3.030 |
2 | 0.358 | −1.611 | 0.008 | −2.764 | −0.457 | 0.056 | −3.446 | 0.411 | −11.880 | 4.988 | 0.249 | −2.229 | 0.184 | −5.574 | 1.116 | |
3 | 0.370 | −1.470 | 0.023 | −2.717 | −0.224 | 0.094 | −3.321 | 0.426 | −11.741 | 5.099 | 0.249 | −2.254 | 0.197 | −5.739 | 1.230 | |
4 | 0.376 | −1.485 | 0.027 | −2.790 | −0.181 | 0.274 | −3.379 | 0.385 | −11.234 | 4.477 | 0.284 | −2.378 | 0.214 | −6.208 | 1.453 | |
5 | 0.402 | −1.658 | 0.030 | −3.132 | −0.183 | 0.541 | −2.652 | 0.457 | −9.899 | 4.595 | 0.315 | −2.340 | 0.245 | −6.386 | 1.707 | |
Manganese (mg) | 1 | 0.036 | −0.313 | 0.315 | −0.939 | 0.314 | 0.004 | 0.612 | 0.724 | −2.888 | 4.111 | 0.000 | 0.020 | 0.978 | −1.440 | 1.479 |
2 | 0.216 | −0.670 | 0.148 | −1.595 | 0.255 | 0.070 | 2.447 | 0.286 | −2.151 | 7.044 | 0.318 | −2.065 | 0.029 | −3.905 | −0.225 | |
3 | 0.259 | −0.548 | 0.243 | −1.492 | 0.397 | 0.110 | 2.437 | 0.286 | −2.147 | 7.020 | 0.319 | −2.116 | 0.031 | −4.029 | −0.202 | |
4 | 0.261 | −0.603 | 0.268 | −1.702 | 0.496 | 0.258 | 0.917 | 0.683 | −3.649 | 5.484 | 0.374 | −2.394 | 0.020 | −4.386 | −0.403 | |
5 | 0.300 | −1.023 | 0.177 | −2.551 | 0.505 | 0.531 | 0.672 | 0.751 | −3.650 | 4.994 | 0.403 | −2.436 | 0.027 | −4.579 | −0.294 | |
Nitrogen (g) | 1 | 0.000 | 0.029 | 0.951 | −0.925 | 0.983 | 0.079 | −4.872 | 0.102 | −10.761 | 1.017 | 0.069 | 1.529 | 0.116 | −0.396 | 3.455 |
2 | 0.159 | −0.492 | 0.540 | −2.124 | 1.140 | 0.151 | −9.958 | 0.051 | −19.945 | 0.028 | 0.207 | 0.307 | 0.849 | −2.949 | 3.564 | |
3 | 0.217 | −0.232 | 0.775 | −1.892 | 1.428 | 0.182 | −9.612 | 0.059 | −19.620 | 0.395 | 0.209 | 0.363 | 0.826 | −2.979 | 3.706 | |
4 | 0.219 | −0.201 | 0.816 | −1.965 | 1.564 | 0.290 | −6.283 | 0.249 | −17.236 | 4.670 | 0.244 | 0.055 | 0.976 | −3.551 | 3.660 | |
5 | 0.227 | −0.073 | 0.941 | −2.088 | 1.943 | 0.539 | −3.647 | 0.482 | −14.194 | 6.899 | 0.279 | −0.286 | 0.878 | −4.078 | 3.506 | |
Phosphorous (mg) | 1 | 0.002 | 0.113 | 0.809 | −0.834 | 1.059 | 0.040 | −3.794 | 0.252 | −10.412 | 2.823 | 0.079 | 1.913 | 0.091 | −0.325 | 4.150 |
2 | 0.150 | −0.317 | 0.743 | −2.289 | 1.654 | 0.080 | −7.676 | 0.228 | −20.427 | 5.075 | 0.206 | 0.152 | 0.954 | −5.234 | 5.538 | |
3 | 0.214 | −0.017 | 0.986 | −2.004 | 1.971 | 0.113 | −7.102 | 0.266 | −19.910 | 5.705 | 0.208 | 0.352 | 0.901 | −5.375 | 6.080 | |
4 | 0.217 | 0.019 | 0.985 | −2.116 | 2.155 | 0.279 | −5.937 | 0.332 | −18.279 | 6.405 | 0.244 | 0.307 | 0.922 | −6.092 | 6.706 | |
5 | 0.227 | 0.046 | 0.968 | −2.321 | 2.414 | 0.544 | −5.139 | 0.396 | −17.430 | 7.152 | 0.278 | −0.356 | 0.917 | −7.329 | 6.617 | |
Potassium (mg) | 1 | 0.093 | −0.631 | 0.101 | −1.395 | 0.132 | 0.041 | −3.221 | 0.244 | −8.742 | 2.301 | 0.034 | 1.259 | 0.276 | −1.051 | 3.569 |
2 | 0.343 | −1.289 | 0.011 | −2.260 | −0.318 | 0.074 | −5.037 | 0.265 | −14.094 | 4.021 | 0.249 | −2.497 | 0.187 | −6.267 | 1.273 | |
3 | 0.359 | −1.165 | 0.029 | −2.199 | −0.131 | 0.103 | −4.377 | 0.338 | −13.563 | 4.810 | 0.249 | −2.577 | 0.197 | −6.564 | 1.410 | |
4 | 0.369 | −1.203 | 0.031 | −2.289 | −0.117 | 0.292 | −5.001 | 0.238 | −13.501 | 3.499 | 0.278 | −2.493 | 0.252 | −6.853 | 1.866 | |
5 | 0.390 | −1.305 | 0.036 | −2.518 | −0.092 | 0.571 | −5.495 | 0.147 | −13.061 | 2.070 | 0.308 | −2.391 | 0.301 | −7.047 | 2.265 | |
Selenium (μg) | 1 | 0.001 | 0.070 | 0.844 | −0.649 | 0.788 | 0.034 | −2.930 | 0.290 | −8.476 | 2.616 | 0.088 | 1.241 | 0.074 | −0.127 | 2.609 |
2 | 0.154 | −0.296 | 0.630 | −1.548 | 0.955 | 0.050 | −2.893 | 0.486 | −11.263 | 5.476 | 0.212 | 0.502 | 0.631 | −1.608 | 2.611 | |
3 | 0.219 | −0.223 | 0.713 | −1.458 | 1.012 | 0.076 | −1.390 | 0.756 | −10.438 | 7.658 | 0.214 | 0.550 | 0.609 | −1.619 | 2.720 | |
4 | 0.221 | −0.210 | 0.741 | −1.513 | 1.092 | 0.254 | −0.467 | 0.921 | −10.095 | 9.161 | 0.246 | 0.352 | 0.749 | −1.882 | 2.586 | |
5 | 0.231 | −0.221 | 0.747 | −1.638 | 1.195 | 0.548 | −4.096 | 0.336 | −12.718 | 4.526 | 0.278 | 0.059 | 0.960 | −2.358 | 2.475 | |
Sodium (mg) | 1 | 0.026 | 0.298 | 0.396 | −0.410 | 1.006 | 0.043 | −2.386 | 0.233 | −6.379 | 1.606 | 0.070 | 1.203 | 0.114 | −0.303 | 2.709 |
2 | 0.167 | 0.429 | 0.440 | −0.696 | 1.553 | 0.071 | −4.127 | 0.279 | −11.770 | 3.516 | 0.208 | −0.339 | 0.802 | −3.072 | 2.394 | |
3 | 0.269 | 0.733 | 0.193 | −0.397 | 1.864 | 0.110 | −4.098 | 0.280 | −11.719 | 3.522 | 0.209 | −0.327 | 0.812 | −3.108 | 2.454 | |
4 | 0.278 | 0.805 | 0.186 | −0.417 | 2.026 | 0.316 | −5.590 | 0.128 | −12.890 | 1.711 | 0.245 | −0.350 | 0.804 | −3.209 | 2.510 | |
5 | 0.303 | 0.938 | 0.166 | −0.426 | 2.302 | 0.537 | −2.196 | 0.541 | −9.513 | 5.121 | 0.282 | −0.535 | 0.716 | −3.521 | 2.451 | |
Zinc (mg) | 1 | 0.002 | 0.104 | 0.811 | −0.777 | 0.985 | 0.037 | −3.221 | 0.270 | −9.062 | 2.621 | 0.092 | 1.805 | 0.068 | −0.144 | 3.754 |
2 | 0.151 | −0.285 | 0.705 | −1.818 | 1.247 | 0.084 | −5.927 | 0.208 | −15.327 | 3.474 | 0.210 | 0.639 | 0.691 | −2.604 | 3.881 | |
3 | 0.215 | −0.045 | 0.952 | −1.594 | 1.504 | 0.141 | −6.936 | 0.142 | −16.332 | 2.459 | 0.211 | 0.653 | 0.689 | −2.645 | 3.951 | |
4 | 0.217 | −0.027 | 0.973 | −1.659 | 1.605 | 0.272 | −3.872 | 0.410 | −13.369 | 5.625 | 0.245 | 0.416 | 0.806 | −3.019 | 3.851 | |
5 | 0.229 | 0.244 | 0.820 | −1.971 | 2.459 | 0.530 | 0.535 | 0.908 | −8.905 | 9.975 | 0.279 | 0.273 | 0.877 | −3.320 | 3.866 |
Mineral | Model | NAP | T2DM | NODAP | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
R2 | Unstandardised | p | 95% CI | R2 | Unstandardised | p | 95% CI | R2 | Unstandardised | p | 95% CI | |||||
B | Lower | Upper | B | Lower | Upper | B | Lower | Upper | ||||||||
Calcium (mg) | 1 | 0.000 | 0.682 | 0.944 | −18.900 | 20.265 | 0.000 | 3.095 | 0.966 | −144.004 | 150.194 | 0.025 | 11.785 | 0.352 | −13.594 | 37.164 |
2 | 0.003 | 1.530 | 0.908 | −25.514 | 28.575 | 0.093 | 94.086 | 0.370 | −117.360 | 305.531 | 0.140 | 0.416 | 0.982 | −36.564 | 37.396 | |
3 | 0.006 | 1.318 | 0.923 | −26.345 | 28.981 | 0.095 | 94.223 | 0.378 | −121.278 | 309.724 | 0.154 | 4.158 | 0.828 | −34.648 | 42.963 | |
4 | 0.055 | −1.750 | 0.905 | −31.605 | 28.104 | 0.345 | 151.133 | 0.123 | −43.802 | 346.068 | 0.233 | 4.652 | 0.806 | −33.719 | 43.023 | |
5 | 0.169 | −4.304 | 0.779 | −35.829 | 27.222 | 0.554 | 211.928 | 0.048 | 2.380 | 421.476 | 0.305 | 3.631 | 0.853 | −36.272 | 43.535 | |
Chloride (mg) | 1 | 0.000 | −0.396 | 0.971 | −22.804 | 22.013 | 0.125 | −115.711 | 0.043 | −227.763 | −3.659 | 0.111 | 16.935 | 0.044 | 0.477 | 33.394 |
2 | 0.003 | −1.419 | 0.940 | −39.663 | 36.826 | 0.205 | −250.464 | 0.035 | −482.368 | −18.559 | 0.165 | 15.112 | 0.338 | −16.512 | 46.736 | |
3 | 0.006 | −3.765 | 0.856 | −46.016 | 38.486 | 0.206 | −249.783 | 0.039 | −486.616 | −12.949 | 0.181 | 16.096 | 0.312 | −15.873 | 48.066 | |
4 | 0.054 | 0.348 | 0.987 | −44.621 | 45.316 | 0.325 | −157.937 | 0.202 | −405.953 | 90.079 | 0.248 | 12.594 | 0.430 | −19.553 | 44.740 | |
5 | 0.167 | 3.869 | 0.865 | −42.829 | 50.567 | 0.468 | −74.265 | 0.573 | −344.241 | 195.710 | 0.316 | 10.893 | 0.501 | −21.922 | 43.708 | |
Copper (mg) | 1 | 0.001 | −1.361 | 0.890 | −21.340 | 18.619 | 0.051 | −77.657 | 0.206 | −200.404 | 45.090 | 0.015 | 5.743 | 0.463 | −9.966 | 21.452 |
2 | 0.005 | −4.421 | 0.814 | −42.569 | 33.727 | 0.087 | −62.201 | 0.431 | −221.550 | 97.148 | 0.175 | −13.480 | 0.255 | −37.185 | 10.225 | |
3 | 0.008 | −5.274 | 0.785 | −44.670 | 34.123 | 0.094 | −73.003 | 0.383 | −242.022 | 96.016 | 0.182 | −12.505 | 0.302 | −36.818 | 11.809 | |
4 | 0.057 | −6.079 | 0.775 | −49.572 | 37.413 | 0.309 | −78.894 | 0.304 | −233.561 | 75.772 | 0.239 | −7.103 | 0.579 | −33.004 | 18.797 | |
5 | 0.166 | −0.005 | 1.000 | −58.549 | 58.538 | 0.469 | −43.971 | 0.561 | −198.733 | 110.791 | 0.313 | −7.846 | 0.555 | −34.827 | 19.134 | |
Iodine (μg) | 1 | 0.015 | 6.774 | 0.508 | −13.910 | 27.458 | 0.011 | 44.089 | 0.559 | −108.095 | 196.274 | 0.003 | −3.376 | 0.751 | −24.832 | 18.080 |
2 | 0.028 | 10.929 | 0.421 | −16.526 | 38.385 | 0.145 | 139.849 | 0.119 | −38.148 | 317.846 | 0.183 | −16.155 | 0.207 | −41.723 | 9.412 | |
3 | 0.029 | 10.675 | 0.444 | −17.574 | 38.924 | 0.149 | 149.525 | 0.121 | −42.249 | 341.299 | 0.183 | −15.662 | 0.296 | −45.737 | 14.413 | |
4 | 0.064 | 7.312 | 0.619 | −22.663 | 37.287 | 0.391 | 177.429 | 0.042 | 7.071 | 347.788 | 0.262 | −17.142 | 0.276 | −48.728 | 14.444 | |
5 | 0.167 | 2.035 | 0.898 | −30.667 | 34.737 | 0.560 | 173.350 | 0.041 | 7.943 | 338.758 | 0.389 | −30.162 | 0.069 | −62.806 | 2.482 | |
Iron (mg) | 1 | 0.003 | 3.297 | 0.755 | −18.119 | 24.712 | 0.099 | −115.820 | 0.075 | −243.956 | 12.315 | 0.065 | 13.101 | 0.129 | −3.999 | 30.202 |
2 | 0.011 | 7.683 | 0.648 | −26.530 | 41.897 | 0.160 | −200.167 | 0.088 | −432.286 | 31.952 | 0.141 | 1.804 | 0.897 | −26.366 | 29.974 | |
3 | 0.012 | 7.195 | 0.679 | −28.208 | 42.597 | 0.162 | −201.193 | 0.092 | −437.755 | 35.369 | 0.153 | 1.665 | 0.906 | −26.784 | 30.113 | |
4 | 0.066 | 10.265 | 0.592 | −28.802 | 49.333 | 0.407 | −245.327 | 0.028 | −462.181 | −28.472 | 0.242 | 9.479 | 0.512 | −19.738 | 38.695 | |
5 | 0.219 | 26.432 | 0.260 | −21.085 | 73.948 | 0.506 | −162.179 | 0.177 | −403.620 | 79.263 | 0.316 | 9.995 | 0.496 | −19.730 | 39.721 | |
Magnesium (mg) | 1 | 0.004 | 4.215 | 0.745 | −22.047 | 30.478 | 0.031 | −69.528 | 0.325 | −211.363 | 72.307 | 0.064 | 16.067 | 0.131 | −5.016 | 37.150 |
2 | 0.013 | 11.065 | 0.615 | −33.550 | 55.680 | 0.070 | −38.358 | 0.729 | −262.673 | 185.957 | 0.142 | 4.207 | 0.826 | −34.552 | 42.967 | |
3 | 0.013 | 10.442 | 0.663 | −38.328 | 59.212 | 0.072 | −38.529 | 0.732 | −267.158 | 190.100 | 0.157 | 7.364 | 0.710 | −32.652 | 47.381 | |
4 | 0.064 | 11.718 | 0.631 | −38.103 | 61.538 | 0.279 | −13.693 | 0.895 | −225.423 | 198.038 | 0.264 | 23.641 | 0.260 | −18.415 | 65.697 | |
5 | 0.178 | 13.735 | 0.599 | −39.821 | 67.291 | 0.467 | 56.533 | 0.604 | −166.590 | 279.656 | 0.346 | 27.072 | 0.205 | −15.765 | 69.909 | |
Manganese (mg) | 1 | 0.011 | 5.508 | 0.569 | −14.050 | 25.066 | 0.041 | −51.721 | 0.256 | −142.781 | 39.339 | 0.021 | 6.635 | 0.395 | −9.016 | 22.286 |
2 | 0.027 | 12.556 | 0.426 | −19.325 | 44.437 | 0.074 | −29.026 | 0.632 | −151.707 | 93.654 | 0.145 | −4.331 | 0.695 | −26.653 | 17.990 | |
3 | 0.027 | 12.358 | 0.457 | −21.338 | 46.054 | 0.076 | −28.812 | 0.640 | −153.877 | 96.254 | 0.155 | −2.854 | 0.803 | −25.954 | 20.246 | |
4 | 0.063 | 8.552 | 0.651 | −30.036 | 47.141 | 0.282 | −21.648 | 0.713 | −141.639 | 98.343 | 0.232 | 1.811 | 0.878 | −22.102 | 25.723 | |
5 | 0.191 | 18.914 | 0.446 | −31.778 | 69.606 | 0.464 | 23.069 | 0.710 | −104.147 | 150.285 | 0.308 | 4.983 | 0.685 | −20.009 | 29.976 | |
Nitrogen (g) | 1 | 0.006 | 6.296 | 0.667 | −23.334 | 35.925 | 0.141 | −164.493 | 0.032 | −313.440 | −15.546 | 0.023 | 9.547 | 0.371 | −11.829 | 30.923 |
2 | 0.026 | 20.629 | 0.436 | −32.961 | 74.219 | 0.220 | −290.208 | 0.026 | −543.873 | −36.544 | 0.149 | −10.206 | 0.574 | −46.762 | 26.350 | |
3 | 0.026 | 20.417 | 0.469 | −36.755 | 77.589 | 0.224 | −293.149 | 0.028 | −551.738 | −34.560 | 0.159 | −8.631 | 0.641 | −45.969 | 28.707 | |
4 | 0.067 | 16.507 | 0.572 | −43.109 | 76.122 | 0.449 | −354.028 | 0.010 | −616.299 | −91.757 | 0.231 | −2.819 | 0.885 | −42.203 | 36.565 | |
5 | 0.205 | 29.712 | 0.336 | −33.177 | 92.601 | 0.557 | −302.235 | 0.043 | −594.534 | −9.936 | 0.309 | −8.424 | 0.670 | −48.642 | 31.795 | |
Phosphorous (mg) | 1 | 0.005 | 5.317 | 0.715 | −24.217 | 34.852 | 0.064 | −124.221 | 0.154 | −297.555 | 49.113 | 0.030 | 12.826 | 0.303 | −12.057 | 37.708 |
2 | 0.028 | 26.005 | 0.417 | −38.750 | 90.760 | 0.104 | −176.359 | 0.291 | −511.914 | 159.195 | 0.154 | −21.636 | 0.470 | −81.865 | 38.594 | |
3 | 0.028 | 25.670 | 0.448 | −42.882 | 94.222 | 0.106 | −180.110 | 0.290 | −522.839 | 162.618 | 0.161 | −17.082 | 0.589 | −80.946 | 46.783 | |
4 | 0.065 | 17.927 | 0.614 | −54.521 | 90.374 | 0.294 | −120.851 | 0.458 | −451.367 | 209.664 | 0.231 | 2.698 | 0.938 | −67.235 | 72.630 | |
5 | 0.181 | 21.602 | 0.558 | −53.968 | 97.173 | 0.461 | −38.232 | 0.840 | −427.352 | 350.887 | 0.306 | 2.698 | 0.938 | −67.235 | 72.630 | |
Potassium (mg) | 1 | 0.006 | 5.082 | 0.680 | −19.831 | 29.995 | 0.004 | −25.770 | 0.734 | −179.222 | 127.681 | 0.038 | 14.536 | 0.245 | −10.432 | 39.504 |
2 | 0.014 | 9.796 | 0.592 | −27.342 | 46.933 | 0.077 | 67.976 | 0.576 | −177.997 | 313.950 | 0.147 | −10.519 | 0.626 | −54.057 | 33.018 | |
3 | 0.014 | 9.292 | 0.637 | −30.771 | 49.355 | 0.078 | 65.721 | 0.599 | −187.360 | 318.802 | 0.156 | −6.998 | 0.758 | −52.818 | 38.823 | |
4 | 0.063 | 9.372 | 0.643 | −31.888 | 50.632 | 0.294 | 83.250 | 0.466 | −148.104 | 314.604 | 0.234 | 8.031 | 0.738 | −40.624 | 56.686 | |
5 | 0.177 | 10.860 | 0.609 | −32.768 | 54.489 | 0.486 | 115.795 | 0.314 | −117.857 | 349.446 | 0.312 | 13.207 | 0.594 | −37.094 | 63.508 | |
Selenium (μg) | 1 | 0.009 | 5.761 | 0.602 | −16.608 | 28.130 | 0.098 | −125.002 | 0.076 | −263.713 | 13.708 | 0.057 | 10.798 | 0.155 | −4.281 | 25.877 |
2 | 0.034 | 18.588 | 0.369 | −23.220 | 60.395 | 0.114 | −127.226 | 0.229 | −339.267 | 84.815 | 0.144 | 4.334 | 0.713 | −19.488 | 28.156 | |
3 | 0.035 | 18.255 | 0.389 | −24.650 | 61.159 | 0.132 | −160.099 | 0.169 | −392.384 | 72.187 | 0.159 | 5.725 | 0.634 | −18.588 | 30.037 | |
4 | 0.076 | 15.940 | 0.464 | −28.303 | 60.183 | 0.287 | −66.978 | 0.582 | −314.052 | 180.097 | 0.236 | 5.128 | 0.670 | −19.252 | 29.508 | |
5 | 0.187 | 15.431 | 0.485 | −29.824 | 60.687 | 0.489 | −126.832 | 0.291 | −370.420 | 116.757 | 0.304 | 0.815 | 0.949 | −24.893 | 26.523 | |
Sodium (mg) | 1 | 0.001 | −1.545 | 0.887 | −23.518 | 20.428 | 0.159 | −130.487 | 0.022 | −240.412 | −20.562 | 0.112 | 16.517 | 0.043 | 0.577 | 32.457 |
2 | 0.005 | −4.201 | 0.818 | −41.446 | 33.043 | 0.275 | −299.924 | 0.008 | −516.198 | −83.650 | 0.167 | 15.217 | 0.315 | −15.142 | 45.576 | |
3 | 0.010 | −6.605 | 0.740 | −47.140 | 33.930 | 0.276 | −299.407 | 0.010 | −520.277 | −78.537 | 0.182 | 15.680 | 0.305 | −14.964 | 46.323 | |
4 | 0.056 | −4.007 | 0.848 | −46.888 | 38.874 | 0.359 | −212.348 | 0.089 | −459.386 | 34.690 | 0.247 | 11.938 | 0.437 | −19.015 | 42.891 | |
5 | 0.167 | 2.849 | 0.898 | −42.868 | 48.566 | 0.489 | −142.541 | 0.288 | −414.470 | 129.388 | 0.314 | 9.383 | 0.547 | −22.242 | 41.008 | |
Zinc (mg) | 1 | 0.004 | 4.532 | 0.737 | −22.804 | 31.869 | 0.213 | −197.213 | 0.007 | −336.116 | −58.310 | 0.035 | 12.018 | 0.270 | −9.755 | 33.791 |
2 | 0.018 | 15.253 | 0.535 | −34.560 | 65.067 | 0.382 | −373.530 | 0.001 | −575.644 | −171.417 | 0.143 | −5.245 | 0.772 | −41.851 | 31.362 | |
3 | 0.018 | 14.702 | 0.573 | −38.378 | 67.781 | 0.386 | −380.543 | 0.001 | −589.288 | −171.797 | 0.155 | −4.778 | 0.794 | −41.776 | 32.220 | |
4 | 0.066 | 14.441 | 0.590 | −40.152 | 69.033 | 0.657 | −445.092 | <0.001 | −619.351 | −270.832 | 0.231 | −1.635 | 0.930 | −39.212 | 35.941 | |
5 | 0.260 | 50.565 | 0.128 | −15.779 | 116.909 | 0.724 | −443.991 | <0.001 | −650.255 | −237.727 | 0.305 | −4.170 | 0.824 | −42.378 | 34.037 |
Mineral | Model | NAP | T2DM | NODAP | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
R2 | Unstandardised | p | 95% CI | R2 | Unstandardised | p | 95% CI | R2 | Unstandardised | p | 95% CI | |||||
B | Lower | Upper | B | Lower | Upper | B | Lower | Upper | ||||||||
Calcium (mg) | 1 | 0.000 | 4.245 | 0.926 | −88.813 | 97.302 | 0.001 | −8.964 | 0.867 | −117.484 | 99.556 | 0.001 | −20.276 | 0.881 | −293.772 | 253.221 |
2 | 0.073 | 23.013 | 0.706 | −101.166 | 147.192 | 0.067 | −18.272 | 0.817 | −179.031 | 142.487 | 0.107 | 114.173 | 0.563 | −283.789 | 512.134 | |
3 | 0.073 | 22.983 | 0.713 | −104.289 | 150.254 | 0.192 | −16.230 | 0.829 | −168.916 | 136.457 | 0.110 | 132.410 | 0.526 | −288.485 | 553.304 | |
4 | 0.154 | 41.110 | 0.533 | −93.534 | 175.754 | 0.223 | −5.025 | 0.950 | −169.995 | 159.946 | 0.229 | 139.137 | 0.489 | −267.284 | 545.558 | |
5 | 0.247 | 66.633 | 0.345 | −77.518 | 210.784 | 0.420 | −88.801 | 0.348 | −281.674 | 104.072 | 0.709 | 57.731 | 0.667 | −215.061 | 330.524 | |
Chloride (mg) | 1 | 0.033 | −51.011 | 0.339 | −158.443 | 56.421 | 0.004 | 15.765 | 0.737 | −79.199 | 110.730 | 0.111 | −180.055 | 0.044 | −355.117 | −4.993 |
2 | 0.086 | −63.180 | 0.477 | −243.526 | 117.166 | 0.086 | 77.326 | 0.432 | −121.453 | 276.104 | 0.178 | −289.538 | 0.086 | −622.669 | 43.594 | |
3 | 0.089 | −72.394 | 0.452 | −268.015 | 123.228 | 0.216 | 82.758 | 0.374 | −105.362 | 270.879 | 0.178 | −289.377 | 0.092 | −629.320 | 50.567 | |
4 | 0.181 | −104.669 | 0.298 | −308.129 | 98.790 | 0.264 | 111.304 | 0.256 | −86.304 | 308.911 | 0.280 | −261.122 | 0.121 | −594.969 | 72.724 | |
5 | 0.246 | −98.220 | 0.355 | −315.089 | 118.648 | 0.400 | 49.419 | 0.637 | −165.851 | 264.689 | 0.750 | −217.292 | 0.044 | −428.069 | −6.514 | |
Copper (mg) | 1 | 0.031 | −43.362 | 0.352 | −137.263 | 50.538 | 0.009 | 24.564 | 0.599 | −69.756 | 118.884 | 0.099 | −154.495 | 0.057 | −314.111 | 5.122 |
2 | 0.092 | −69.511 | 0.416 | −242.574 | 103.551 | 0.102 | 60.255 | 0.299 | −56.496 | 177.005 | 0.146 | −170.409 | 0.186 | −427.502 | 86.684 | |
3 | 0.093 | −71.292 | 0.418 | −249.976 | 107.392 | 0.199 | 30.092 | 0.604 | −87.746 | 147.929 | 0.146 | −171.753 | 0.196 | −436.630 | 93.124 | |
4 | 0.165 | −78.492 | 0.413 | −273.392 | 116.408 | 0.228 | 22.564 | 0.707 | −99.655 | 144.782 | 0.309 | −253.252 | 0.058 | −515.926 | 9.422 | |
5 | 0.212 | −31.411 | 0.815 | −308.032 | 245.211 | 0.283 | 10.249 | 0.871 | −119.765 | 140.263 | 0.745 | −167.033 | 0.061 | −342.373 | 8.307 | |
Iodine (μg) | 1 | 0.004 | −15.292 | 0.755 | −114.575 | 83.990 | 0.010 | 30.916 | 0.579 | −81.679 | 143.511 | 0.020 | −94.323 | 0.404 | −320.836 | 132.190 |
2 | 0.067 | 4.789 | 0.939 | −123.720 | 133.298 | 0.087 | 56.379 | 0.421 | −85.043 | 197.802 | 0.108 | −85.555 | 0.543 | −368.826 | 197.716 | |
3 | 0.067 | 4.607 | 0.943 | −127.926 | 137.140 | 0.192 | 14.082 | 0.842 | −129.786 | 157.951 | 0.109 | −100.274 | 0.542 | −432.233 | 231.685 | |
4 | 0.146 | 28.682 | 0.670 | −109.020 | 166.384 | 0.226 | 24.852 | 0.743 | −130.091 | 179.795 | 0.220 | −62.038 | 0.715 | −405.720 | 281.644 | |
5 | 0.238 | 60.435 | 0.415 | −91.349 | 212.218 | 0.282 | 3.760 | 0.964 | −165.192 | 172.712 | 0.730 | 166.340 | 0.149 | −63.802 | 396.482 | |
Iron (mg) | 1 | 0.051 | −59.579 | 0.231 | −159.174 | 40.016 | 0.000 | −1.752 | 0.973 | −107.430 | 103.927 | 0.115 | −185.833 | 0.040 | −363.132 | −8.535 |
2 | 0.109 | −82.280 | 0.286 | −237.781 | 73.220 | 0.067 | 24.843 | 0.789 | −164.093 | 213.779 | 0.165 | −233.936 | 0.116 | −528.950 | 61.077 | |
3 | 0.111 | −85.085 | 0.287 | −246.254 | 76.083 | 0.192 | 14.699 | 0.868 | −165.163 | 194.562 | 0.166 | −234.282 | 0.121 | −534.284 | 65.720 | |
4 | 0.206 | −114.133 | 0.186 | −287.501 | 59.234 | 0.226 | 30.623 | 0.755 | −169.964 | 231.209 | 0.352 | −346.007 | 0.020 | −633.371 | −58.643 | |
5 | 0.254 | −115.084 | 0.302 | −342.302 | 112.134 | 0.282 | 3.634 | 0.972 | −211.245 | 218.513 | 0.815 | −311.717 | 0.001 | −476.081 | −147.352 | |
Magnesium (mg) | 1 | 0.003 | −19.157 | 0.758 | −145.201 | 106.887 | 0.000 | −2.214 | 0.967 | −110.488 | 106.061 | 0.037 | −129.590 | 0.256 | −357.405 | 98.225 |
2 | 0.068 | 12.933 | 0.899 | −194.469 | 220.335 | 0.065 | 2.267 | 0.978 | −163.449 | 167.982 | 0.102 | −83.355 | 0.690 | −505.305 | 338.596 | |
3 | 0.068 | 13.362 | 0.904 | −212.038 | 238.763 | 0.191 | 0.629 | 0.994 | −156.748 | 158.006 | 0.102 | −80.624 | 0.711 | −520.302 | 359.053 | |
4 | 0.138 | 6.492 | 0.953 | −221.286 | 234.269 | 0.223 | 9.332 | 0.906 | −152.865 | 171.528 | 0.251 | −255.197 | 0.258 | −707.649 | 197.254 | |
5 | 0.217 | 48.798 | 0.688 | −201.321 | 298.916 | 0.288 | −38.814 | 0.670 | −225.826 | 148.199 | 0.744 | −270.454 | 0.062 | −556.016 | 15.109 | |
Manganese (mg) | 1 | 0.033 | −44.415 | 0.337 | −137.646 | 48.815 | 0.025 | −29.789 | 0.387 | −99.021 | 39.444 | 0.018 | −64.901 | 0.434 | −231.423 | 101.621 |
2 | 0.107 | −75.452 | 0.299 | −221.969 | 71.064 | 0.085 | −34.271 | 0.443 | −124.527 | 55.986 | 0.097 | −8.935 | 0.941 | −252.480 | 234.611 | |
3 | 0.110 | −80.190 | 0.292 | −233.884 | 73.504 | 0.210 | −33.277 | 0.432 | −118.905 | 52.352 | 0.098 | −5.432 | 0.965 | −259.170 | 248.305 | |
4 | 0.157 | −58.269 | 0.495 | −232.216 | 115.678 | 0.259 | −47.567 | 0.288 | −137.956 | 42.823 | 0.219 | −38.405 | 0.761 | −294.475 | 217.665 | |
5 | 0.210 | 0.653 | 0.996 | −240.491 | 241.797 | 0.369 | −82.329 | 0.102 | −182.399 | 17.741 | 0.708 | −27.175 | 0.749 | −199.621 | 145.271 | |
Nitrogen (g) | 1 | 0.038 | −71.506 | 0.304 | −211.519 | 68.508 | 0.015 | 42.746 | 0.499 | −84.772 | 170.264 | 0.070 | −177.381 | 0.113 | −398.803 | 44.041 |
2 | 0.112 | −137.456 | 0.271 | −389.188 | 114.275 | 0.111 | 124.875 | 0.248 | −92.253 | 342.003 | 0.146 | −258.927 | 0.184 | −647.304 | 129.451 | |
3 | 0.116 | −146.926 | 0.263 | −411.659 | 117.807 | 0.223 | 105.339 | 0.308 | −102.865 | 313.543 | 0.147 | −260.240 | 0.193 | −659.486 | 139.006 | |
4 | 0.174 | −127.030 | 0.343 | −399.145 | 145.084 | 0.314 | 213.001 | 0.087 | −33.151 | 459.154 | 0.281 | −317.497 | 0.119 | −721.219 | 86.225 | |
5 | 0.259 | −157.445 | 0.278 | −452.534 | 137.643 | 0.370 | 224.107 | 0.101 | −47.412 | 495.625 | 0.732 | −202.711 | 0.129 | −468.542 | 63.121 | |
Phosphorous (mg) | 1 | 0.012 | −39.950 | 0.563 | −179.722 | 99.821 | 0.004 | 22.295 | 0.741 | −114.093 | 158.684 | 0.029 | −133.702 | 0.311 | −397.468 | 130.064 |
2 | 0.072 | −51.373 | 0.734 | −359.027 | 256.282 | 0.080 | 84.240 | 0.504 | −170.846 | 339.326 | 0.102 | −132.413 | 0.687 | −794.890 | 530.063 | |
3 | 0.072 | −54.417 | 0.729 | −375.257 | 266.423 | 0.200 | 65.482 | 0.585 | −178.166 | 309.130 | 0.102 | −129.617 | 0.710 | −833.766 | 574.532 | |
4 | 0.138 | −7.089 | 0.965 | −340.158 | 325.981 | 0.243 | 98.521 | 0.432 | −156.148 | 353.190 | 0.241 | −353.553 | 0.340 | −1099.203 | 392.097 | |
5 | 0.212 | 31.093 | 0.857 | −325.047 | 387.233 | 0.286 | 56.721 | 0.713 | −259.758 | 373.200 | 0.720 | −269.348 | 0.284 | −775.847 | 237.152 | |
Potassium (mg) | 1 | 0.003 | −16.429 | 0.781 | −136.370 | 103.512 | 0.004 | 18.905 | 0.736 | −94.355 | 132.165 | 0.027 | −128.753 | 0.334 | −395.441 | 137.936 |
2 | 0.067 | 3.992 | 0.962 | −168.705 | 176.690 | 0.082 | 64.340 | 0.479 | −119.569 | 248.249 | 0.097 | −1.281 | 0.996 | −478.077 | 475.515 | |
3 | 0.067 | 3.486 | 0.969 | −182.688 | 189.661 | 0.198 | 40.995 | 0.639 | −136.289 | 218.279 | 0.098 | 9.198 | 0.971 | −496.937 | 515.333 | |
4 | 0.138 | 2.516 | 0.978 | −186.768 | 191.800 | 0.233 | 49.116 | 0.585 | −133.876 | 232.109 | 0.229 | −172.371 | 0.502 | −691.495 | 346.753 | |
5 | 0.215 | 35.293 | 0.723 | −170.311 | 240.896 | 0.282 | 13.879 | 0.892 | −195.396 | 223.154 | 0.723 | −206.074 | 0.222 | −544.658 | 132.510 | |
Selenium (μg) | 1 | 0.082 | −79.157 | 0.126 | −181.980 | 23.665 | 0.002 | −11.955 | 0.832 | −126.209 | 102.300 | 0.156 | −190.212 | 0.015 | −341.928 | −38.496 |
2 | 0.174 | −161.698 | 0.084 | −346.864 | 23.467 | 0.065 | −9.716 | 0.905 | −175.647 | 156.215 | 0.270 | −316.557 | 0.010 | −550.548 | −82.565 | |
3 | 0.175 | −163.257 | 0.089 | −353.246 | 26.733 | 0.225 | −88.172 | 0.294 | −257.424 | 81.081 | 0.272 | −321.541 | 0.010 | −562.267 | −80.815 | |
4 | 0.229 | −150.724 | 0.121 | −344.671 | 43.224 | 0.239 | −65.983 | 0.483 | −256.883 | 124.918 | 0.365 | −301.402 | 0.014 | −538.260 | −64.544 | |
5 | 0.284 | −136.762 | 0.178 | −341.488 | 67.963 | 0.287 | −41.705 | 0.682 | −250.337 | 166.927 | 0.751 | −170.803 | 0.042 | −334.944 | −6.663 | |
Sodium (mg) | 1 | 0.045 | −58.808 | 0.260 | −163.574 | 45.959 | 0.004 | 16.363 | 0.733 | −80.536 | 113.262 | 0.124 | −184.187 | 0.033 | −352.486 | −15.889 |
2 | 0.106 | −88.626 | 0.307 | −263.553 | 86.301 | 0.091 | 87.005 | 0.384 | −114.584 | 288.594 | 0.199 | −311.853 | 0.052 | −626.458 | 2.752 | |
3 | 0.111 | −98.167 | 0.289 | −285.097 | 88.764 | 0.221 | 93.598 | 0.322 | −97.008 | 284.204 | 0.199 | −311.400 | 0.056 | −631.659 | 8.858 | |
4 | 0.203 | −124.509 | 0.194 | −317.339 | 68.320 | 0.281 | 137.051 | 0.176 | −65.969 | 340.071 | 0.298 | −283.647 | 0.077 | −599.697 | 32.403 | |
5 | 0.271 | −126.663 | 0.223 | −336.940 | 83.615 | 0.343 | 144.558 | 0.175 | −69.341 | 358.456 | 0.754 | −218.425 | 0.033 | −418.330 | −18.520 | |
Zinc (mg) | 1 | 0.023 | −51.834 | 0.420 | −181.514 | 77.846 | 0.025 | 55.468 | 0.385 | −72.923 | 183.859 | 0.073 | −183.978 | 0.105 | −408.329 | 40.372 |
2 | 0.085 | −78.844 | 0.495 | −313.081 | 155.394 | 0.112 | 125.731 | 0.243 | −90.458 | 341.919 | 0.145 | −252.328 | 0.191 | −637.361 | 132.704 | |
3 | 0.086 | −83.949 | 0.488 | −329.674 | 161.776 | 0.273 | 169.479 | 0.098 | −33.648 | 372.607 | 0.145 | −251.641 | 0.200 | −643.524 | 140.241 | |
4 | 0.158 | −86.306 | 0.480 | −335.522 | 162.909 | 0.377 | 289.421 | 0.023 | 43.866 | 534.977 | 0.264 | −258.584 | 0.182 | −645.443 | 128.275 | |
5 | 0.229 | −105.373 | 0.507 | −431.429 | 220.683 | 0.419 | 309.600 | 0.037 | 20.715 | 598.485 | 0.742 | −224.960 | 0.070 | −469.860 | 19.940 |
Mineral | Model | NAP | T2DM | NODAP | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
R2 | Unstandardised | p | 95% CI | R2 | Unstandardised | p | 95% CI | R2 | Unstandardised | p | 95% CI | |||||
B | Lower | Upper | B | Lower | Upper | B | Lower | Upper | ||||||||
Calcium (mg) | 1 | 0.000 | −5.939 | 0.924 | −131.853 | 119.975 | 0.026 | 59.501 | 0.375 | −75.352 | 194.355 | 0.002 | −14.743 | 0.801 | −132.376 | 102.890 |
2 | 0.012 | −6.229 | 0.942 | −179.720 | 167.261 | 0.073 | 77.512 | 0.436 | −123.813 | 278.838 | 0.045 | −38.284 | 0.665 | −216.884 | 140.317 | |
3 | 0.026 | −9.389 | 0.914 | −185.937 | 167.158 | 0.082 | 78.258 | 0.439 | −126.297 | 282.813 | 0.045 | −36.058 | 0.700 | −224.993 | 152.877 | |
4 | 0.096 | −29.370 | 0.750 | −218.038 | 159.298 | 0.199 | 100.850 | 0.333 | −109.921 | 311.621 | 0.122 | −31.336 | 0.736 | −219.349 | 156.676 | |
5 | 0.207 | −49.778 | 0.609 | −249.916 | 150.361 | 0.323 | 212.290 | 0.108 | −51.282 | 475.862 | 0.242 | −36.731 | 0.696 | −227.639 | 154.177 | |
Chloride (mg) | 1 | 0.000 | −6.794 | 0.926 | −154.426 | 140.838 | 0.015 | 39.754 | 0.501 | −79.372 | 158.881 | 0.054 | 54.184 | 0.166 | −23.594 | 131.962 |
2 | 0.012 | −3.849 | 0.975 | −257.061 | 249.363 | 0.062 | 68.869 | 0.583 | −185.206 | 322.944 | 0.143 | 141.793 | 0.058 | −5.019 | 288.606 | |
3 | 0.028 | −31.997 | 0.811 | −305.099 | 241.105 | 0.071 | 71.013 | 0.577 | −187.234 | 329.259 | 0.147 | 144.009 | 0.058 | −5.501 | 293.518 | |
4 | 0.092 | −3.160 | 0.982 | −292.529 | 286.208 | 0.174 | 61.822 | 0.633 | −201.737 | 325.382 | 0.201 | 128.137 | 0.095 | −23.649 | 279.924 | |
5 | 0.197 | 17.586 | 0.904 | −284.210 | 319.383 | 0.239 | 81.685 | 0.583 | −223.503 | 386.873 | 0.304 | 116.500 | 0.126 | −35.158 | 268.159 | |
Copper (mg) | 1 | 0.001 | 7.765 | 0.903 | −121.090 | 136.620 | 0.017 | 41.359 | 0.482 | −77.394 | 160.112 | 0.004 | 14.096 | 0.695 | −58.279 | 86.471 |
2 | 0.016 | 34.751 | 0.772 | −209.890 | 279.392 | 0.053 | 17.738 | 0.812 | −134.068 | 169.543 | 0.039 | 6.490 | 0.911 | −110.693 | 123.673 | |
3 | 0.027 | 24.732 | 0.841 | −226.887 | 276.350 | 0.060 | 7.625 | 0.923 | −153.952 | 169.202 | 0.041 | 8.557 | 0.886 | −112.062 | 129.176 | |
4 | 0.093 | 19.065 | 0.887 | −256.912 | 295.043 | 0.168 | 16.570 | 0.833 | −143.875 | 177.016 | 0.136 | 46.493 | 0.458 | −79.998 | 172.984 | |
5 | 0.201 | 64.828 | 0.724 | −314.034 | 443.690 | 0.228 | 11.032 | 0.897 | −164.469 | 186.533 | 0.251 | 42.761 | 0.502 | −86.363 | 171.884 | |
Iodine (μg) | 1 | 0.008 | 30.782 | 0.640 | −102.706 | 164.271 | 0.046 | 81.841 | 0.240 | −57.529 | 221.212 | 0.022 | −42.133 | 0.386 | −139.513 | 55.247 |
2 | 0.029 | 56.302 | 0.518 | −120.504 | 233.109 | 0.098 | 101.984 | 0.249 | −75.679 | 279.648 | 0.072 | −64.920 | 0.297 | −189.764 | 59.923 | |
3 | 0.039 | 50.674 | 0.570 | −130.679 | 232.027 | 0.098 | 98.086 | 0.303 | −93.617 | 289.789 | 0.076 | −78.239 | 0.285 | −224.781 | 68.303 | |
4 | 0.095 | 23.215 | 0.803 | −167.908 | 214.337 | 0.225 | 127.661 | 0.189 | −67.401 | 322.723 | 0.141 | −66.715 | 0.389 | −222.844 | 89.415 | |
5 | 0.197 | −15.199 | 0.881 | −225.146 | 194.748 | 0.309 | 158.222 | 0.140 | −56.457 | 372.901 | 0.322 | −137.836 | 0.084 | −295.371 | 19.699 | |
Iron (mg) | 1 | 0.007 | 30.044 | 0.658 | −107.487 | 167.575 | 0.035 | 66.164 | 0.308 | −64.121 | 196.449 | 0.035 | 44.412 | 0.265 | −35.151 | 123.976 |
2 | 0.034 | 79.261 | 0.461 | −138.613 | 297.135 | 0.076 | 98.022 | 0.403 | −138.853 | 334.898 | 0.079 | 77.703 | 0.245 | −55.889 | 211.295 | |
3 | 0.043 | 70.665 | 0.523 | −154.431 | 295.761 | 0.083 | 95.313 | 0.424 | −145.887 | 336.513 | 0.081 | 77.519 | 0.253 | −58.319 | 213.357 | |
4 | 0.123 | 104.201 | 0.387 | −140.508 | 348.909 | 0.168 | 30.333 | 0.813 | −231.155 | 291.821 | 0.202 | 117.228 | 0.091 | −20.114 | 254.570 | |
5 | 0.276 | 206.316 | 0.165 | −92.421 | 505.054 | 0.230 | 35.933 | 0.801 | −258.075 | 329.941 | 0.323 | 119.810 | 0.081 | −15.689 | 255.309 | |
Magnesium (mg) | 1 | 0.012 | 47.893 | 0.566 | −121.097 | 216.883 | 0.010 | 37.288 | 0.578 | −98.261 | 172.836 | 0.018 | 39.442 | 0.424 | −59.480 | 138.364 |
2 | 0.048 | 134.307 | 0.338 | −148.960 | 417.574 | 0.054 | 27.146 | 0.794 | −183.772 | 238.064 | 0.074 | 100.091 | 0.277 | −84.314 | 284.497 | |
3 | 0.051 | 120.287 | 0.429 | −188.080 | 428.655 | 0.062 | 26.630 | 0.800 | −187.738 | 240.998 | 0.080 | 109.211 | 0.254 | −82.253 | 300.675 | |
4 | 0.122 | 130.433 | 0.395 | −181.386 | 442.253 | 0.167 | 16.960 | 0.870 | −195.391 | 229.310 | 0.228 | 195.903 | 0.052 | −1.449 | 393.255 | |
5 | 0.225 | 137.590 | 0.405 | −200.651 | 475.831 | 0.231 | 34.706 | 0.778 | −219.204 | 288.617 | 0.359 | 209.968 | 0.035 | 15.617 | 404.319 | |
Manganese (mg) | 1 | 0.028 | 55.427 | 0.378 | −71.380 | 182.235 | 0.005 | 16.415 | 0.707 | −71.921 | 104.751 | 0.010 | 21.010 | 0.558 | −51.092 | 93.113 |
2 | 0.071 | 123.704 | 0.221 | −79.364 | 326.773 | 0.052 | −3.069 | 0.957 | −119.040 | 112.901 | 0.050 | 32.472 | 0.544 | −75.283 | 140.227 | |
3 | 0.075 | 116.172 | 0.271 | −96.576 | 328.920 | 0.060 | −2.711 | 0.963 | −120.579 | 115.156 | 0.054 | 36.441 | 0.512 | −75.538 | 148.420 | |
4 | 0.115 | 87.295 | 0.463 | −155.219 | 329.809 | 0.174 | 26.902 | 0.649 | −93.552 | 147.355 | 0.161 | 67.896 | 0.235 | −46.563 | 182.354 | |
5 | 0.233 | 148.215 | 0.348 | −174.149 | 470.580 | 0.228 | 6.949 | 0.921 | −136.888 | 150.786 | 0.301 | 86.001 | 0.137 | −29.129 | 201.130 | |
Nitrogen (g) | 1 | 0.009 | 45.855 | 0.628 | −145.675 | 237.384 | 0.028 | 72.596 | 0.361 | −87.307 | 232.498 | 0.001 | 10.020 | 0.838 | −89.000 | 109.040 |
2 | 0.059 | 187.715 | 0.277 | −160.518 | 535.947 | 0.079 | 122.556 | 0.377 | −157.318 | 402.431 | 0.039 | −2.024 | 0.982 | −179.990 | 175.943 | |
3 | 0.063 | 173.300 | 0.338 | −192.896 | 539.496 | 0.085 | 117.196 | 0.407 | −168.841 | 403.233 | 0.040 | 0.506 | 0.996 | −182.241 | 183.252 | |
4 | 0.117 | 144.646 | 0.436 | −233.597 | 522.889 | 0.167 | −23.512 | 0.888 | −365.757 | 318.734 | 0.127 | 48.643 | 0.609 | −143.703 | 240.989 | |
5 | 0.253 | 229.907 | 0.243 | −169.685 | 629.500 | 0.228 | −24.832 | 0.898 | −421.984 | 372.320 | 0.239 | 19.193 | 0.840 | −174.203 | 212.590 | |
Phosphorous (mg) | 1 | 0.003 | 27.993 | 0.766 | −162.724 | 218.710 | 0.015 | 57.456 | 0.499 | −114.202 | 229.114 | 0.000 | 7.146 | 0.901 | −108.600 | 122.893 |
2 | 0.045 | 188.086 | 0.367 | −233.295 | 609.466 | 0.060 | 78.072 | 0.627 | −247.944 | 404.089 | 0.039 | −13.901 | 0.924 | −308.039 | 280.237 | |
3 | 0.051 | 169.357 | 0.435 | −271.236 | 609.950 | 0.067 | 71.617 | 0.662 | −261.259 | 404.493 | 0.040 | −5.683 | 0.971 | −318.630 | 307.265 | |
4 | 0.103 | 113.980 | 0.613 | −346.970 | 574.930 | 0.167 | 17.031 | 0.918 | −321.290 | 355.353 | 0.134 | 117.914 | 0.484 | −222.170 | 457.998 | |
5 | 0.208 | 126.685 | 0.590 | −356.433 | 609.803 | 0.234 | 85.992 | 0.685 | −349.189 | 521.173 | 0.240 | 54.466 | 0.755 | −300.687 | 409.619 | |
Potassium (mg) | 1 | 0.018 | 56.300 | 0.477 | −103.819 | 216.419 | 0.006 | 30.712 | 0.663 | −111.969 | 173.394 | 0.008 | 29.688 | 0.607 | −86.520 | 145.896 |
2 | 0.047 | 109.673 | 0.347 | −125.983 | 345.328 | 0.051 | −1.282 | 0.991 | −235.386 | 232.821 | 0.047 | 51.782 | 0.620 | −159.087 | 262.650 | |
3 | 0.051 | 97.860 | 0.434 | −155.787 | 351.506 | 0.060 | −8.590 | 0.942 | −248.425 | 231.244 | 0.050 | 62.325 | 0.572 | −160.321 | 284.971 | |
4 | 0.119 | 101.462 | 0.425 | −157.261 | 360.184 | 0.166 | −2.926 | 0.980 | −241.369 | 235.517 | 0.161 | 138.053 | 0.236 | −95.225 | 371.330 | |
5 | 0.222 | 105.443 | 0.434 | −170.771 | 381.657 | 0.228 | 18.263 | 0.892 | −259.878 | 296.404 | 0.293 | 162.286 | 0.165 | −71.287 | 395.858 | |
Selenium (μg) | 1 | 0.013 | 43.158 | 0.544 | −100.802 | 187.119 | 0.069 | 102.133 | 0.146 | −37.525 | 241.791 | 0.017 | 26.818 | 0.445 | −43.726 | 97.362 |
2 | 0.068 | 157.873 | 0.231 | −107.040 | 422.786 | 0.132 | 155.801 | 0.125 | −45.927 | 357.530 | 0.065 | 52.255 | 0.358 | −61.844 | 166.354 | |
3 | 0.078 | 152.266 | 0.257 | −118.360 | 422.893 | 0.133 | 162.882 | 0.151 | −63.501 | 389.264 | 0.068 | 55.403 | 0.343 | −61.864 | 172.670 | |
4 | 0.132 | 135.082 | 0.323 | −142.104 | 412.269 | 0.215 | 144.228 | 0.235 | −99.935 | 388.390 | 0.151 | 60.494 | 0.302 | −57.238 | 178.226 | |
5 | 0.232 | 128.958 | 0.356 | −156.548 | 414.464 | 0.268 | 141.726 | 0.305 | −139.159 | 422.612 | 0.249 | 37.843 | 0.530 | −84.499 | 160.185 | |
Sodium (mg) | 1 | 0.001 | −12.310 | 0.863 | −156.880 | 132.261 | 0.007 | 27.329 | 0.651 | −94.818 | 149.477 | 0.056 | 53.368 | 0.159 | −21.949 | 128.684 |
2 | 0.013 | −17.939 | 0.882 | −264.710 | 228.832 | 0.051 | 4.073 | 0.975 | −256.284 | 264.431 | 0.145 | 137.731 | 0.055 | −3.231 | 278.693 | |
3 | 0.030 | −43.199 | 0.737 | −305.709 | 219.310 | 0.060 | 5.845 | 0.964 | −258.847 | 270.537 | 0.147 | 138.601 | 0.058 | −4.721 | 281.923 | |
4 | 0.094 | −24.835 | 0.854 | −300.837 | 251.166 | 0.167 | −18.877 | 0.889 | −295.000 | 257.246 | 0.199 | 121.615 | 0.100 | −24.696 | 267.927 | |
5 | 0.196 | 14.467 | 0.919 | −280.912 | 309.846 | 0.228 | −20.252 | 0.897 | −341.472 | 300.969 | 0.297 | 105.786 | 0.150 | −40.874 | 252.447 | |
Zinc (mg) | 1 | 0.003 | 27.139 | 0.756 | −150.344 | 204.621 | 0.002 | 22.001 | 0.786 | −141.899 | 185.901 | 0.002 | 11.563 | 0.818 | −89.887 | 113.012 |
2 | 0.038 | 131.442 | 0.418 | −197.461 | 460.345 | 0.051 | −2.183 | 0.987 | −284.797 | 280.430 | 0.039 | 6.272 | 0.943 | −171.268 | 183.813 | |
3 | 0.045 | 115.778 | 0.494 | −228.626 | 460.181 | 0.060 | 9.784 | 0.946 | −281.729 | 301.297 | 0.041 | 6.966 | 0.938 | −173.654 | 187.585 | |
4 | 0.111 | 115.634 | 0.501 | −235.095 | 466.363 | 0.204 | −180.999 | 0.299 | −533.080 | 171.082 | 0.123 | 34.254 | 0.706 | −149.606 | 218.113 | |
5 | 0.296 | 335.168 | 0.117 | −91.712 | 762.049 | 0.256 | −180.723 | 0.394 | −613.285 | 251.839 | 0.239 | 18.785 | 0.835 | −164.458 | 202.028 |
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Norbitt, C.F.; Kimita, W.; Ko, J.; Bharmal, S.H.; Petrov, M.S. Associations of Habitual Mineral Intake with New-Onset Prediabetes/Diabetes after Acute Pancreatitis. Nutrients 2021, 13, 3978. https://doi.org/10.3390/nu13113978
Norbitt CF, Kimita W, Ko J, Bharmal SH, Petrov MS. Associations of Habitual Mineral Intake with New-Onset Prediabetes/Diabetes after Acute Pancreatitis. Nutrients. 2021; 13(11):3978. https://doi.org/10.3390/nu13113978
Chicago/Turabian StyleNorbitt, Claire F., Wandia Kimita, Juyeon Ko, Sakina H. Bharmal, and Maxim S. Petrov. 2021. "Associations of Habitual Mineral Intake with New-Onset Prediabetes/Diabetes after Acute Pancreatitis" Nutrients 13, no. 11: 3978. https://doi.org/10.3390/nu13113978
APA StyleNorbitt, C. F., Kimita, W., Ko, J., Bharmal, S. H., & Petrov, M. S. (2021). Associations of Habitual Mineral Intake with New-Onset Prediabetes/Diabetes after Acute Pancreatitis. Nutrients, 13(11), 3978. https://doi.org/10.3390/nu13113978