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Review

Beta-Glucans from Fungi: Biological and Health-Promoting Potential in the COVID-19 Pandemic Era

Department of Food Biotechnology, Faculty of Health Sciences, Medical University of Bialystok, Szpitalna 37, 15-295 Bialystok, Poland
*
Author to whom correspondence should be addressed.
Academic Editor: Jose M. Soriano
Nutrients 2021, 13(11), 3960; https://doi.org/10.3390/nu13113960
Received: 18 October 2021 / Revised: 4 November 2021 / Accepted: 4 November 2021 / Published: 6 November 2021
Beta-glucans comprise a group of polysaccharides of natural origin found in bacteria, algae, and plants, e.g., cereal seeds, as well as microfungi and macrofungi (mushrooms), which are characterized by diverse structures and functions. They are known for their metabolic and immunomodulatory properties, including anticancer, antibacterial, and antiviral. Recent reports suggest a potential of beta-glucans in the prevention and treatment of COVID-19. In contrast to β-glucans from other sources, β-glucans from mushrooms are characterized by β-1,3-glucans with short β-1,6-side chains. This structure is recognized by receptors located on the surface of immune cells; thus, mushroom β-glucans have specific immunomodulatory properties and gained BRM (biological response modifier) status. Moreover, mushroom beta-glucans also owe their properties to the formation of triple helix conformation, which is one of the key factors influencing the bioactivity of mushroom beta-glucans. This review summarizes the latest findings on biological and health-promoting potential of mushroom beta-glucans for the treatment of civilization and viral diseases, with particular emphasis on COVID-19. View Full-Text
Keywords: β-glucans; macrofungi; mushrooms; food; SARS-CoV-2; COVID-19 β-glucans; macrofungi; mushrooms; food; SARS-CoV-2; COVID-19
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MDPI and ACS Style

Mirończuk-Chodakowska, I.; Kujawowicz, K.; Witkowska, A.M. Beta-Glucans from Fungi: Biological and Health-Promoting Potential in the COVID-19 Pandemic Era. Nutrients 2021, 13, 3960. https://doi.org/10.3390/nu13113960

AMA Style

Mirończuk-Chodakowska I, Kujawowicz K, Witkowska AM. Beta-Glucans from Fungi: Biological and Health-Promoting Potential in the COVID-19 Pandemic Era. Nutrients. 2021; 13(11):3960. https://doi.org/10.3390/nu13113960

Chicago/Turabian Style

Mirończuk-Chodakowska, Iwona, Karolina Kujawowicz, and Anna M. Witkowska. 2021. "Beta-Glucans from Fungi: Biological and Health-Promoting Potential in the COVID-19 Pandemic Era" Nutrients 13, no. 11: 3960. https://doi.org/10.3390/nu13113960

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