How to Tackle the Relationship between Autoimmune Diseases and Diet: Well Begun Is Half-Done
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Department of Health Sciences, Interdisciplinary Research Center of Autoimmune Diseases—IRCAD, Università del Piemonte Orientale, 28100 Novara, Italy
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Center for Translational Research on Autoimmune and Allergic Disease—CAAD, Università del Piemonte Orientale, 28100 Novara, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Francisco J. Pérez-Cano
Nutrients 2021, 13(11), 3956; https://doi.org/10.3390/nu13113956
Received: 1 October 2021
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Revised: 29 October 2021
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Accepted: 3 November 2021
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Published: 5 November 2021
(This article belongs to the Special Issue Evolution, Current Reality and Future of Dietary Assessment)
Nutrition and immunity are closely related, and the immune system is composed of the most highly energy-consuming cells in the body. Much of the immune system is located within the GI tract, since it must deal with the huge antigenic load introduced with food. Moreover, the incidence of immune-mediated diseases is elevated in Westernized countries, where “transition nutrition” prevails, owing to the shift from traditional dietary patterns towards Westernized patterns. This ecological correlation has fostered increasing attempts to find evidence to support nutritional interventions aimed at managing and reducing the risk of immune-mediated diseases. Recent studies have described the impacts of single nutrients on markers of immune function, but the knowledge currently available is not sufficient to demonstrate the impact of specific dietary patterns on immune-mediated clinical disease endpoints. If nutritional scientists are to conduct quality research, one of many challenges facing them, in studying the complex interactions between the immune system and diet, is to develop improved tools for investigating eating habits in the context of immunomediated diseases.
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Keywords:
nutrition; dietary assessment; nutritional immunology; Mediterranean diet; western diet; nutritional immunology; autoimmune diseases
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MDPI and ACS Style
Mazzucca, C.B.; Raineri, D.; Cappellano, G.; Chiocchetti, A. How to Tackle the Relationship between Autoimmune Diseases and Diet: Well Begun Is Half-Done. Nutrients 2021, 13, 3956. https://doi.org/10.3390/nu13113956
AMA Style
Mazzucca CB, Raineri D, Cappellano G, Chiocchetti A. How to Tackle the Relationship between Autoimmune Diseases and Diet: Well Begun Is Half-Done. Nutrients. 2021; 13(11):3956. https://doi.org/10.3390/nu13113956
Chicago/Turabian StyleMazzucca, Camilla B., Davide Raineri, Giuseppe Cappellano, and Annalisa Chiocchetti. 2021. "How to Tackle the Relationship between Autoimmune Diseases and Diet: Well Begun Is Half-Done" Nutrients 13, no. 11: 3956. https://doi.org/10.3390/nu13113956
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