Next Article in Journal
Quercetin Supplementation Improves Neuromuscular Function Recovery from Muscle Damage
Previous Article in Journal
Is Drinking Alcohol Really Linked to Cardiovascular Health? Evidence from the Kardiovize 2030 Project
Open AccessArticle

Association of Maternal Plasma Total Cysteine and Growth among Infants in Nepal: A Cohort Study

1
Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, 5020 Bergen, Norway
2
Centre for Intervention Science in Maternal and Child Health, Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, 5020 Bergen, Norway
3
Department of Research, Innlandet Hospital Trust, 2609 Lillehammer, Norway
4
Department of Community Medicine, Kathmandu Medical College, Kathmandu 44600, Nepal
5
Department of Physiology, Faculty of Medicine, University of Alexandria, Alexandria 21131, Egypt
6
Department of Pharmacology, University of Oxford, Oxford OX13QT, UK
7
Department of Child Health, Institute of Medicine, Tribhuvan University, Kathmandu 44600, Nepal
8
Department of Clinical Science, University of Bergen, 5020 Bergen, Norway
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(9), 2849; https://doi.org/10.3390/nu12092849
Received: 18 August 2020 / Revised: 14 September 2020 / Accepted: 14 September 2020 / Published: 17 September 2020
(This article belongs to the Section Micronutrients and Human Health)
Cysteine is a semi-essential amino acid that has been positively associated with growth in children. However, transgenerational effects remain unclear. The aim of this analysis was to assess whether maternal plasma total cysteine (tCys) concentration is associated with various growth indicators in infants living in peri-urban settings in Bhaktapur, Nepal. We used data from the 561 mothers enrolled in an ongoing randomized controlled trial. We built linear regression models to evaluate the associations between maternal tCys and birth weight, length-for-age Z-scores (LAZ) and weight-for-length Z-scores (WLZ) at birth and six months of age. Maternal tCys was inversely associated with birth weight among boys after adjusting for confounders (p < 0.05). In addition, there was a negative association between maternal tCys and LAZ at birth (p < 0.01). No associations between maternal tCys and the other anthropometric indicators were found significant, although there was a tendency for maternal tCys to be associated positively with WLZ at birth among girls (p < 0.10). This is a first study evaluating transgenerational relation of tCys on growth in infants. Further, larger and more comprehensive studies are needed to determine if and how maternal tCys alters child growth. View Full-Text
Keywords: amino acid; metabolism; tCys; malnutrition; weight; length; child; stunting; wasting; Asia amino acid; metabolism; tCys; malnutrition; weight; length; child; stunting; wasting; Asia
Show Figures

Figure 1

MDPI and ACS Style

Arora, N.; Strand, T.A.; Chandyo, R.K.; Elshorbagy, A.; Shrestha, L.; Ueland, P.M.; Ulak, M.; Schwinger, C. Association of Maternal Plasma Total Cysteine and Growth among Infants in Nepal: A Cohort Study. Nutrients 2020, 12, 2849.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop