Next Article in Journal
Effect of Co-Administration of Panax ginseng and Brassica oleracea on Postmenopausal Osteoporosis in Ovariectomized Mice
Previous Article in Journal
Association of Serum Fatty Acids at Admission with the Age of Onset of Acute Ischemic Stroke
Open AccessArticle

Frozen Autoclaved Sorghum Enhanced Colonic Fermentation and Lower Visceral Fat Accumulation in Rats

1
Department of Life and Food Sciences, Obihiro University of Agriculture and Veterinary Medicine, West 2-11, Inada, Obihiro 080–8555, Hokkaido, Japan
2
Research Center for Global Agromedicine, Obihiro University of Agriculture and Veterinary Medicine, West 2-11, Inada, Obihiro 080-8555, Hokkaido, Japan
3
Division of Aerospace Medicine, Department of Cell Physiology, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minatoku, Tokyo 105-8461, Japan
4
U.S. Grains Council, 11th Floor, Toranomon Denki Building No. 3, 1-2-20 Toranomon, Minato-ku, Tokyo 105-0001, Japan
5
Nakano Industry Co., Asahishinmachi 33-25 Takamatsu, Kagawa 760-0064, Japan
*
Author to whom correspondence should be addressed.
This work was part of Samanthi W. Pelpolage’s PhD thesis.
Nutrients 2020, 12(8), 2412; https://doi.org/10.3390/nu12082412
Received: 14 July 2020 / Revised: 5 August 2020 / Accepted: 10 August 2020 / Published: 12 August 2020
(This article belongs to the Section Prebiotics and Probiotics)
As raw sorghum is not able to influence considerable colonic fermentation despite its higher resistant starch (RS) content, our study aimed to investigate the effects of frozen autoclaved sorghum on colonic fermentation. Fischer 344 rats were fed frozen cooked refined (S-Rf) and whole (S-Wh) sorghum diets and were compared against α-corn starch (CON) and high amylose starch (HAS) fed rats for zoometric parameters, cecal biochemical and microbiological parameters. Sorghum fed rats exhibited significantly lower feed intake and visceral adipose tissue mass compared to CON. Bacterial alpha diversity was significantly higher in the sorghum fed rats compared to HAS and the two sorghum fed groups clustered together, separately from HAS and CON in the beta diversity plot. Serum non-High Density Lipoprotein cholesterol and total cholesterol in S-Rf group were significantly lower compared to CON, while total fecal bile excretion was also significantly higher in the two sorghum fed groups. Lower visceral adiposity was correlated with lower feed intake, RS content ingested and cecal short chain fatty acid (SCFA) contents. Thus, higher RS inflow to the colon via frozen autoclaved sorghum might have influenced colonic fermentation of RS and the resultant SCFA might have influenced lower adiposity as manifested by the lower body weight gain. View Full-Text
Keywords: colonic fermentation; lipid metabolism; sorghum; visceral fat colonic fermentation; lipid metabolism; sorghum; visceral fat
Show Figures

Graphical abstract

MDPI and ACS Style

Pelpolage, S.W.; Yoshida, A.; Nagata, R.; Shimada, K.; Fukuma, N.; Bochimoto, H.; Hamamoto, T.; Hoshizawa, M.; Nakano, K.; Han, K.-H.; Fukushima, M. Frozen Autoclaved Sorghum Enhanced Colonic Fermentation and Lower Visceral Fat Accumulation in Rats. Nutrients 2020, 12, 2412. https://doi.org/10.3390/nu12082412

AMA Style

Pelpolage SW, Yoshida A, Nagata R, Shimada K, Fukuma N, Bochimoto H, Hamamoto T, Hoshizawa M, Nakano K, Han K-H, Fukushima M. Frozen Autoclaved Sorghum Enhanced Colonic Fermentation and Lower Visceral Fat Accumulation in Rats. Nutrients. 2020; 12(8):2412. https://doi.org/10.3390/nu12082412

Chicago/Turabian Style

Pelpolage, Samanthi W.; Yoshida, Atsushi; Nagata, Ryuji; Shimada, Kenichiro; Fukuma, Naoki; Bochimoto, Hiroki; Hamamoto, Tetsuo; Hoshizawa, Michiyo; Nakano, Koichi; Han, Kyu-Ho; Fukushima, Michihiro. 2020. "Frozen Autoclaved Sorghum Enhanced Colonic Fermentation and Lower Visceral Fat Accumulation in Rats" Nutrients 12, no. 8: 2412. https://doi.org/10.3390/nu12082412

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop