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Article

Effect of Porcine Placenta Extract Supplement on Skin Condition in Healthy Adult Women: A Randomized, Double-Blind Placebo-Controlled Study

1
Faculty of Agriculture, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan
2
Healthcare Business Unit, Kasyu Industries Co., Ltd., 2-5-3 Minami-Futajima, Wakamatsu-ku, Kitakyusyu, Fukuoka 808-0109, Japan
3
Department of Biological and Environmental Chemistry, Kinki University Kyushu, Kayanomori, Izuka, Fukuoka 820-8555, Japan
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(6), 1671; https://doi.org/10.3390/nu12061671
Received: 9 April 2020 / Revised: 22 May 2020 / Accepted: 1 June 2020 / Published: 4 June 2020
(This article belongs to the Section Clinical Nutrition)
Placenta extract has been used as a component of ointments for skin dryness and beautification. However, little is known about the effect of oral intake of placenta extract on skin condition. The current study aimed to clinically explore the effect of oral intake of porcine placenta extract on human skin quality. A randomized controlled double-blind trial was performed on healthy women aged 40–59 years (n = 20), who were randomly assigned to receive either placebo or 200 mg of porcine placenta extract once daily for 4 weeks from 28 January 2019 to 25 February 2019. Skin quality parameters and the Simplified Menopausal Index (SMI) were assessed at baseline and after 4 weeks. After 4 weeks, three parameters of skin quality were significantly improved in the porcine placenta group compared with the placebo group. These results suggest that porcine placenta extract can be used as a health food ingredient to maintain humans’ skin condition in the dry winter season. View Full-Text
Keywords: porcine placenta extract; skin hydration; skin barrier function; skin elasticity; menopausal symptoms porcine placenta extract; skin hydration; skin barrier function; skin elasticity; menopausal symptoms
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MDPI and ACS Style

Nagae, M.; Nagata, M.; Teramoto, M.; Yamakawa, M.; Matsuki, T.; Ohnuki, K.; Shimizu, K. Effect of Porcine Placenta Extract Supplement on Skin Condition in Healthy Adult Women: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients 2020, 12, 1671. https://doi.org/10.3390/nu12061671

AMA Style

Nagae M, Nagata M, Teramoto M, Yamakawa M, Matsuki T, Ohnuki K, Shimizu K. Effect of Porcine Placenta Extract Supplement on Skin Condition in Healthy Adult Women: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2020; 12(6):1671. https://doi.org/10.3390/nu12061671

Chicago/Turabian Style

Nagae, Masumi, Maki Nagata, Mitsuhiro Teramoto, Masayuki Yamakawa, Takahiro Matsuki, Koichiro Ohnuki, and Kuniyoshi Shimizu. 2020. "Effect of Porcine Placenta Extract Supplement on Skin Condition in Healthy Adult Women: A Randomized, Double-Blind Placebo-Controlled Study" Nutrients 12, no. 6: 1671. https://doi.org/10.3390/nu12061671

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