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Large Variability of Iodine Content in Retail Cow’s Milk in the U.S.

U.S. Department of Agriculture, Agricultural Research Service, Methods and Application of Food Composition Laboratory, Beltsville, MD 20705, USA
Biochemistry Department, Virginia Tech, Blacksburg, VA 24061, USA
Department of Nutrition and Food Science, College of Agriculture and Natural Resources, University of Maryland, College Park, MD 20742, USA
National Institutes of Health, Office of Dietary Supplements, Bethesda, MD 20892, USA
Author to whom correspondence should be addressed.
Nutrients 2020, 12(5), 1246;
Received: 24 March 2020 / Revised: 16 April 2020 / Accepted: 22 April 2020 / Published: 28 April 2020
(This article belongs to the Section Micronutrients and Human Health)
Iodine intake is of contemporary public health interest. The recommended daily iodine intake is 150 µg for most adults, and milk is an important source of iodine in the U.S. diet. Iodine concentration in cow’s milk is affected by diet and iodine supplementation levels, milking sanitation practices, and other factors. Current analytical iodine data in U.S. retail milk are crucial for evaluating population-wide health outcomes related to diet. Samples of whole (3.25% fat), 2%, 1%, and skim (0–0.5% fat) milk were procured from 24 supermarkets across the U.S. using a census-based statistical plan. Iodine was analyzed by inductively coupled plasma mass spectrometry, including certified reference materials and control samples to validate results. No difference in iodine content was found between milkfat levels (F3,69 1.033, p = 0.4). Overall mean (SEM) was 85(5.5) µg/serving (240 mL). However, the 95% prediction interval of 39–185 µg/serving for individual samples indicated high variability among individual samples. Given the recommended 150 µg iodine per day for most adults along with the study mean, one milk serving can provide approximately 57% of daily intake. Researchers, health care professionals, and consumers should be aware of iodine variability in milk, while additional research is needed to investigate the impact of iodine variability factors. View Full-Text
Keywords: iodine; milk; food composition; iodophors; intake; variability iodine; milk; food composition; iodophors; intake; variability
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MDPI and ACS Style

Roseland, J.M.; Phillips, K.M.; Patterson, K.Y.; Pehrsson, P.R.; Bahadur, R.; Ershow, A.G.; Somanchi, M. Large Variability of Iodine Content in Retail Cow’s Milk in the U.S. Nutrients 2020, 12, 1246.

AMA Style

Roseland JM, Phillips KM, Patterson KY, Pehrsson PR, Bahadur R, Ershow AG, Somanchi M. Large Variability of Iodine Content in Retail Cow’s Milk in the U.S. Nutrients. 2020; 12(5):1246.

Chicago/Turabian Style

Roseland, Janet M., Katherine M. Phillips, Kristine Y. Patterson, Pamela R. Pehrsson, Rahul Bahadur, Abby G. Ershow, and Meena Somanchi. 2020. "Large Variability of Iodine Content in Retail Cow’s Milk in the U.S." Nutrients 12, no. 5: 1246.

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