Next Article in Journal
Factors Associated with Frequency of Peanut Consumption in Korea: A National Population-Based Study
Next Article in Special Issue
Effects of Olive Oil on Blood Pressure: Epidemiological, Clinical, and Mechanistic Evidence
Previous Article in Journal
The Impact of Aerobic Exercise and Badminton on HDL Cholesterol Levels in Taiwanese Adults
Open AccessArticle

Anti-Fatigue Effect of Prunus Mume Vinegar in High-Intensity Exercised Rats

1
Department of Food Science and Technology, Kyungpook National University, Daegu 41566, Korea
2
Institute of Agricultural Life Sciences, Dong-A University, Busan 49315, Korea
3
Department of Food Biotechnology, Dong-A University, Busan 49315, Korea
4
College of Pharmacy and Gachon Institute of Pharmaceutical Science, Gachon University, Incheon 21936, Korea
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(5), 1205; https://doi.org/10.3390/nu12051205
Received: 2 April 2020 / Revised: 21 April 2020 / Accepted: 23 April 2020 / Published: 25 April 2020
(This article belongs to the Special Issue Health-Promoting Components of Foods in Human Health)
Nowadays, new types of vinegar have been developed using various raw materials and biotechnological processes. The fruit of Prunus mume has been extensively distributed in East Asia and used as a folk medication for fatigue. In this study, the Prunus mume vinegar (PV) was produced by a two-step fermentation and was evaluated for its anti-fatigue activity by C2C12 myoblasts and high-intensity exercised rats. The administration of PV significantly improved running endurance and glycogen accumulation in the liver and muscle of PV supplemented rats compared to sedentary and exercised control groups. In addition, PV supplementation elicited lower fatigue-related serum biomarkers, for instance, ammonia, inorganic phosphate, and lactate. PV administered rats exhibited higher lactate dehydrogenase activity and glutathione peroxidase activity, and lower creatine kinase activity and malondialdehyde levels. Furthermore, phenolic compounds in PV were identified using HPLC analysis. The phenolic acids analyzed in PV were protocatechuic acid, syringic acid, chlorogenic acid, and its derivates. These results indicate that the administration of PV with antioxidative property contributes to the improvement of fatigue recovery in exhausted rats. The findings of this study suggest that the PV containing various bioactive constituents can be used as a functional material against fatigue caused by high-intensity exercise. View Full-Text
Keywords: prunus mume; vinegar; anti-fatigue effect; high-intensity exercise; phenolic acid prunus mume; vinegar; anti-fatigue effect; high-intensity exercise; phenolic acid
Show Figures

Figure 1

MDPI and ACS Style

Kim, J.-H.; Cho, H.-D.; Won, Y.-S.; Hong, S.-M.; Moon, K.-D.; Seo, K.-I. Anti-Fatigue Effect of Prunus Mume Vinegar in High-Intensity Exercised Rats. Nutrients 2020, 12, 1205.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop