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Effects of Ashwagandha (Withania somnifera) on VO2max: A Systematic Review and Meta-Analysis

1
HEME Research Group, Faculty of Sport Sciences, University of Extremadura, 10003 Caceres, Spain
2
Physical Activity and Quality of Life Research Group (AFYCAV), Faculty of Sport Science, University of Extremadura, 10003 Cáceres, Spain
3
Facultad de Educación, Universidad Autónoma de Chile, Talca 3460000, Chile
4
Centre for Sport Studies, Rey Juan Carlos University, Fuenlabrada, 28943 Madrid, Spain
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(4), 1119; https://doi.org/10.3390/nu12041119
Received: 15 March 2020 / Revised: 9 April 2020 / Accepted: 14 April 2020 / Published: 17 April 2020
(This article belongs to the Special Issue Nutrition and Athletic Performance)
The purpose of this study was to systematically review the scientific literature about the effects of supplementation with Ashwagandha (Withania somnifera) on maximum oxygen consumption (VO2max), as well as to provide directions for clinical practice. A systematic search was conducted in three electronic databases following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines (PRISMA). The inclusion criteria were: (a) VO2max data, with means ± standard deviation before and after the supplement intervention, (b) the study was randomized controlled trial (RCT), (c) the article was written in English. The quality of evidence was evaluated according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. A meta-analysis was performed to determine effect sizes. Five studies were selected in the systematic review (162 participants) and four were included in the meta-analysis (142 participants). Results showed a significant enhancement in VO2max in healthy adults and athletes (p = 0.04). The mean difference was 3.00 (95% CI from 0.18 to 5.82) with high heterogeneity. In conclusion, Ashwagandha supplementation might improve the VO2max in athlete and non-athlete people. However, further research is need to confirm this hypothesis since the number of studies is limited and the heterogeneity was high. View Full-Text
Keywords: ergogenic aids; maximum oxygen consumption; performance sports; physical fitness ergogenic aids; maximum oxygen consumption; performance sports; physical fitness
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MDPI and ACS Style

Pérez-Gómez, J.; Villafaina, S.; Adsuar, J.C.; Merellano-Navarro, E.; Collado-Mateo, D. Effects of Ashwagandha (Withania somnifera) on VO2max: A Systematic Review and Meta-Analysis. Nutrients 2020, 12, 1119. https://doi.org/10.3390/nu12041119

AMA Style

Pérez-Gómez J, Villafaina S, Adsuar JC, Merellano-Navarro E, Collado-Mateo D. Effects of Ashwagandha (Withania somnifera) on VO2max: A Systematic Review and Meta-Analysis. Nutrients. 2020; 12(4):1119. https://doi.org/10.3390/nu12041119

Chicago/Turabian Style

Pérez-Gómez, Jorge; Villafaina, Santos; Adsuar, José C.; Merellano-Navarro, Eugenio; Collado-Mateo, Daniel. 2020. "Effects of Ashwagandha (Withania somnifera) on VO2max: A Systematic Review and Meta-Analysis" Nutrients 12, no. 4: 1119. https://doi.org/10.3390/nu12041119

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