Physiological Impact of Palm Olein or Palm Oil in Infant Formulas: A Review of Clinical Evidence
1
Abbott Nutrition R&D, Granada University Science Park, 18016 Granada, Spain
2
Abbott Nutrition R&D, Abbott Laboratories, 18004 Granada, Spain
3
Scientific & Medical Affairs, Abbott Nutrition, Abbott Laboratories, Columbus, OH 43219, USA
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(12), 3676; https://doi.org/10.3390/nu12123676
Received: 31 October 2020
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Revised: 24 November 2020
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Accepted: 26 November 2020
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Published: 28 November 2020
(This article belongs to the Section Nutrition and Public Health)
Palm oil/olein (PO/POL) is used in infant formulas to imitate the fatty acid profile of human milk (HM) and achieve similar levels of palmitic acid (PA). However, the positions of fatty acids on the triacylglyceride differ between PO/POL and HM, which affect fat absorption and produce unintended physiological consequences. Recent papers have reviewed evidence for physiological benefits of PO/POL and beta-palmitate (sn-2-palmitate) in infant formulas. The aim of the present review is to supplement the assessment of available clinical evidence on the physiological effects of PO/POL formulas in healthy infants. We intend to focus on PO/POL and not on sn-2-palmitate, since the latter was recently extensively reviewed. Clinical evidence supports that PO/POL in infant formulas leads to a lower fat, DHA, palmitate and calcium absorption, and bone mineralization; soft stools; and growth (weight accretion) compared to formulas without PO/POL. Consequently, it seems prudent to be considerate and cautious when adding PO/POL to infant formulas. While HM is the gold standard for infant nutrition, the development of infant formula should be based on achieving positive physiological outcomes, rather than just replicating HM nutrient composition.
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Keywords:
palm olein; infant formulas; calcium absorption; fat absorption; DHA absorption; bone mineralization; stool consistency; weight accretion
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MDPI and ACS Style
Padial-Jaudenes, M.; Castanys-Munoz, E.; Ramirez, M.; Lasekan, J. Physiological Impact of Palm Olein or Palm Oil in Infant Formulas: A Review of Clinical Evidence. Nutrients 2020, 12, 3676. https://doi.org/10.3390/nu12123676
AMA Style
Padial-Jaudenes M, Castanys-Munoz E, Ramirez M, Lasekan J. Physiological Impact of Palm Olein or Palm Oil in Infant Formulas: A Review of Clinical Evidence. Nutrients. 2020; 12(12):3676. https://doi.org/10.3390/nu12123676
Chicago/Turabian StylePadial-Jaudenes, Maria, Esther Castanys-Munoz, Maria Ramirez, and John Lasekan. 2020. "Physiological Impact of Palm Olein or Palm Oil in Infant Formulas: A Review of Clinical Evidence" Nutrients 12, no. 12: 3676. https://doi.org/10.3390/nu12123676
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