Sweet Taste Antagonist Lactisole Administered in Combination with Sucrose, But Not Glucose, Increases Energy Intake and Decreases Peripheral Serotonin in Male Subjects
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Population
2.2. Study Design and Intervention
2.2.1. Subjects’ Rating of Hunger
2.2.2. Total Energy Intake
2.3. Blood Sample Collection
2.4. Determination of Postprandial Ghrelin, CCK, and Serotonin Plasma Concentrations
2.5. Body Core and Skin Temperature
2.6. Statistical Analysis
3. Results
3.1. Assessment of Subjects’ Feeling of Hunger by Means of Visual Analogue Scale
3.2. Total Energy Intake after an Ad Libitum Breakfast
3.3. Body Core and Body Skin Temperature
3.4. Plasma Concentrations of Ghrelin, CCK, and Serotonin
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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n | 27 |
---|---|
Gender | Male |
Age [years] | 28 ± 5 |
Body Weight [kg] | 77.4 ± 12 |
Height [m] | 1.81 ± 0.1 |
BMI [kg/m2] | 23.8 ± 2.7 |
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Schweiger, K.; Grüneis, V.; Treml, J.; Galassi, C.; Karl, C.M.; Ley, J.P.; Krammer, G.E.; Lieder, B.; Somoza, V. Sweet Taste Antagonist Lactisole Administered in Combination with Sucrose, But Not Glucose, Increases Energy Intake and Decreases Peripheral Serotonin in Male Subjects. Nutrients 2020, 12, 3133. https://doi.org/10.3390/nu12103133
Schweiger K, Grüneis V, Treml J, Galassi C, Karl CM, Ley JP, Krammer GE, Lieder B, Somoza V. Sweet Taste Antagonist Lactisole Administered in Combination with Sucrose, But Not Glucose, Increases Energy Intake and Decreases Peripheral Serotonin in Male Subjects. Nutrients. 2020; 12(10):3133. https://doi.org/10.3390/nu12103133
Chicago/Turabian StyleSchweiger, Kerstin, Verena Grüneis, Julia Treml, Claudia Galassi, Corinna M. Karl, Jakob P. Ley, Gerhard E. Krammer, Barbara Lieder, and Veronika Somoza. 2020. "Sweet Taste Antagonist Lactisole Administered in Combination with Sucrose, But Not Glucose, Increases Energy Intake and Decreases Peripheral Serotonin in Male Subjects" Nutrients 12, no. 10: 3133. https://doi.org/10.3390/nu12103133
APA StyleSchweiger, K., Grüneis, V., Treml, J., Galassi, C., Karl, C. M., Ley, J. P., Krammer, G. E., Lieder, B., & Somoza, V. (2020). Sweet Taste Antagonist Lactisole Administered in Combination with Sucrose, But Not Glucose, Increases Energy Intake and Decreases Peripheral Serotonin in Male Subjects. Nutrients, 12(10), 3133. https://doi.org/10.3390/nu12103133