Short-Term Effect of One-Anastomosis Gastric Bypass on Essential Fatty Acids in the Serum of Obese Patients
by
Adriana Mika 1,2,*
, Maciej Wilczynski 3, Alicja Pakiet 2, Lukasz Kaska 3, Monika Proczko-Stepaniak 3, Marta Stankiewicz 4, 
Piotr Stepnowski 2 and Tomasz Sledzinski 1
Adriana Mika 1,2,*, Maciej Wilczynski 3, Alicja Pakiet 2, Lukasz Kaska 3, Monika Proczko-Stepaniak 3, Marta Stankiewicz 4, Piotr Stepnowski 2 and Tomasz Sledzinski 1
1
Department of Pharmaceutical Biochemistry, Faculty of Pharmacy, Medical University of Gdansk, 1 Debinki, 80-211 Gdansk, Poland
2
Department of Environmental Analytics, Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308 Gdansk, Poland
3
Department of General, Endocrine, and Transplant Surgery, Faculty of Medicine, Medical University of Gdansk, Smoluchowskiego 17, 80-214 Gdansk, Poland
4
Department of Clinical Nutrition, Faculty of Health Sciences, Medical University of Gdansk, Debinki 7, 80-211 Gdansk, Poland
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(1), 187; https://doi.org/10.3390/nu12010187
Received: 20 November 2019 / Revised: 3 January 2020 / Accepted: 4 January 2020 / Published: 9 January 2020
(This article belongs to the Section Nutrition and Metabolism)
One-anastomosis gastric bypass is a promising type of bariatric surgery, but it may lead to a deficiency in important nutrients, such as fatty acids. The short-term effects of one-anastomosis gastric bypass on serum fatty acids have not been studied thus far. Therefore, the aim of this study was to determine the effect of one-anastomosis gastric bypass on serum fatty acid composition two weeks after surgery. This study included 38 patients who underwent one-anastomosis gastric bypass as surgical treatment for morbid obesity. Serum fatty acid composition was analyzed before and two weeks after surgery using gas chromatography–mass spectrometry. We observed a decrease in essential polyunsaturated fatty acids (p < 0.001 for linolenic acid and p < 0.001 for linoleic acid) and odd-chain fatty acids (p = 0.004) in the serum of obese patients shortly after a one-anastomosis gastric bypass. Considering the benefits of the aforementioned fatty acids for human health, the implementation of a fatty-acid-rich diet or the use of supplementation may be recommended for patients immediately after one-anastomosis gastric bypass.
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MDPI and ACS Style
Mika, A.; Wilczynski, M.; Pakiet, A.; Kaska, L.; Proczko-Stepaniak, M.; Stankiewicz, M.; Stepnowski, P.; Sledzinski, T. Short-Term Effect of One-Anastomosis Gastric Bypass on Essential Fatty Acids in the Serum of Obese Patients. Nutrients 2020, 12, 187.
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