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Dietary Patterns and Renal Health Outcomes in the General Population: A Review Focusing on Prospective Studies

Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20817, USA
National Institutes of Health Graduate Partnerships Program, Bethesda, MD 20817, USA
Department of Public Health Sciences, Clemson University, Clemson, SC 29634, USA
Author to whom correspondence should be addressed.
Nutrients 2019, 11(8), 1877;
Received: 9 July 2019 / Revised: 7 August 2019 / Accepted: 9 August 2019 / Published: 13 August 2019
(This article belongs to the Special Issue Targeted Nutrition in Chronic Disease)
Healthy dietary patterns may promote kidney health and prevent adverse renal outcomes. Although reviews have summarized the findings from studies on dietary patterns for chronic kidney disease (CKD) management, less is known about dietary patterns for maintaining kidney health prior to CKD development. The current review summarized the results from observational studies from March 2009 to March 2019 investigating associations between dietary patterns and renal outcomes in the general population. The main renal outcome assessed was CKD (estimated glomerular filtration rate < 60 mL/min/1.73 m2). A total of twenty-six research articles met the inclusion criteria. Adherence to the Dietary Approaches to Stop Hypertension (DASH) and Mediterranean diets were significantly associated with a decreased risk of CKD in the majority of the studies. Furthermore, a posteriori “unhealthy” dietary patterns were associated with an increased risk of CKD. In conclusion, the findings from this review suggest that adherence to DASH and Mediterranean dietary patterns may be useful in promoting kidney health and preventing CKD in the general population. More studies, in particular among minorities, are warranted to investigate the role of diet, a potentially modifiable factor, in promoting kidney health. View Full-Text
Keywords: dietary pattern; diet; kidney; kidney disease; prevention dietary pattern; diet; kidney; kidney disease; prevention
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Ajjarapu, A.S.; Hinkle, S.N.; Li, M.; Francis, E.C.; Zhang, C. Dietary Patterns and Renal Health Outcomes in the General Population: A Review Focusing on Prospective Studies. Nutrients 2019, 11, 1877.

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