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Unexplained Variance in Hydration Study

Hydration Status and Cardiovascular Function

Department of Kinesiology and Applied Physiology, University of Delaware, Newark, DE 19713, USA
Author to whom correspondence should be addressed.
Nutrients 2019, 11(8), 1866;
Received: 22 June 2019 / Revised: 30 July 2019 / Accepted: 8 August 2019 / Published: 11 August 2019
(This article belongs to the Special Issue Water Intake, Body Water Regulation and Health)
Hypohydration, defined as a state of low body water, increases thirst sensations, arginine vasopressin release, and elicits renin–angiotensin–aldosterone system activation to replenish intra- and extra-cellular fluid stores. Hypohydration impairs mental and physical performance, but new evidence suggests hypohydration may also have deleterious effects on cardiovascular health. This is alarming because cardiovascular disease is the leading cause of death in the United States. Observational studies have linked habitual low water intake with increased future risk for adverse cardiovascular events. While it is currently unclear how chronic reductions in water intake may predispose individuals to greater future risk for adverse cardiovascular events, there is evidence that acute hypohydration impairs vascular function and blood pressure (BP) regulation. Specifically, acute hypohydration may reduce endothelial function, increase sympathetic nervous system activity, and worsen orthostatic tolerance. Therefore, the purpose of this review is to present the currently available evidence linking acute hypohydration with altered vascular function and BP regulation. View Full-Text
Keywords: hypohydration; vascular function; sympathetic nervous system; blood pressure regulation hypohydration; vascular function; sympathetic nervous system; blood pressure regulation
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MDPI and ACS Style

Watso, J.C.; Farquhar, W.B. Hydration Status and Cardiovascular Function. Nutrients 2019, 11, 1866.

AMA Style

Watso JC, Farquhar WB. Hydration Status and Cardiovascular Function. Nutrients. 2019; 11(8):1866.

Chicago/Turabian Style

Watso, Joseph C., and William B. Farquhar. 2019. "Hydration Status and Cardiovascular Function" Nutrients 11, no. 8: 1866.

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