Next Article in Journal
Increased Dietary Inflammatory Index Is Associated with Schizophrenia: Results of a Case–Control Study from Bahrain
Next Article in Special Issue
Deuterium-Depleted Water Influence on the Isotope 2H/1H Regulation in Body and Individual Adaptation
Previous Article in Journal
Effects of Moderate Chronic Food Restriction on the Development of Postprandial Dyslipidemia with Ageing
Previous Article in Special Issue
Unexplained Variance in Hydration Study
Article Menu

Export Article

Open AccessFeature PaperReview

Hydration Status and Cardiovascular Function

Department of Kinesiology and Applied Physiology, University of Delaware, Newark, DE 19713, USA
*
Author to whom correspondence should be addressed.
Nutrients 2019, 11(8), 1866; https://doi.org/10.3390/nu11081866
Received: 22 June 2019 / Revised: 30 July 2019 / Accepted: 8 August 2019 / Published: 11 August 2019
(This article belongs to the Special Issue Water Intake, Body Water Regulation and Health)
  |  
PDF [720 KB, uploaded 12 August 2019]
  |  

Abstract

Hypohydration, defined as a state of low body water, increases thirst sensations, arginine vasopressin release, and elicits renin–angiotensin–aldosterone system activation to replenish intra- and extra-cellular fluid stores. Hypohydration impairs mental and physical performance, but new evidence suggests hypohydration may also have deleterious effects on cardiovascular health. This is alarming because cardiovascular disease is the leading cause of death in the United States. Observational studies have linked habitual low water intake with increased future risk for adverse cardiovascular events. While it is currently unclear how chronic reductions in water intake may predispose individuals to greater future risk for adverse cardiovascular events, there is evidence that acute hypohydration impairs vascular function and blood pressure (BP) regulation. Specifically, acute hypohydration may reduce endothelial function, increase sympathetic nervous system activity, and worsen orthostatic tolerance. Therefore, the purpose of this review is to present the currently available evidence linking acute hypohydration with altered vascular function and BP regulation. View Full-Text
Keywords: hypohydration; vascular function; sympathetic nervous system; blood pressure regulation hypohydration; vascular function; sympathetic nervous system; blood pressure regulation
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Watso, J.C.; Farquhar, W.B. Hydration Status and Cardiovascular Function. Nutrients 2019, 11, 1866.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top