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Effects of Moringa oleifera on Glycaemia and Insulin Levels: A Review of Animal and Human Studies

School of Medicine, Universidad de los Andes, Bogotá 111711, Colombia
School of Medicine, Universidad Antonio Nariño, Bogotá 110231, Colombia
Universidad del Rosario, Escuela de Medicina y Ciencias de la Salud, GI en Neurociencias-NeURos, Bogotá 111221, Colombia
Authors to whom correspondence should be addressed.
Nutrients 2019, 11(12), 2907;
Received: 2 September 2019 / Revised: 9 October 2019 / Accepted: 15 October 2019 / Published: 2 December 2019
Diabetes and related neurological complications are serious worldwide public health problems. The increasing number of affected individuals make it necessary to implement novel nutritional and therapeutic interventions. The tree Moringa oleifera (MO) has been used as a food source and for traditional medicine purposes due to possible antihyperglycemic, antioxidant, anti-inflammatory, and lipid regulating properties. These properties may be explained by the presence of numerous phytochemicals in the leaves, fruits, roots and, oil of the tree. The evidence for acute antihyperglycemic effects of MO extract on diabetic animal models seems to be robust, but more chronic and long-term studies are needed. In contrast, the hypoglycemic effects of MO on humans are not as clear. The scarce number of human studies, together with a diverse range of methodologies and MO doses, may explain this. In addition, evidence regarding changes in insulin levels due to MO intervention is ambiguous, both in animal and human studies. Therefore, more structured studies are needed to clarify if MO has an effect on insulin levels or activity. View Full-Text
Keywords: Moringa oleifera; insulin; diabetes; metabolism Moringa oleifera; insulin; diabetes; metabolism
MDPI and ACS Style

Vargas-Sánchez, K.; Garay-Jaramillo, E.; González-Reyes, R.E. Effects of Moringa oleifera on Glycaemia and Insulin Levels: A Review of Animal and Human Studies. Nutrients 2019, 11, 2907.

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