Bioaccessibility and Bioavailability of a Marine-Derived Multimineral, Aquamin-Magnesium
AbstractIntroduction: Magnesium is an essential mineral involved in a range of key biochemical pathways. Several magnesium supplements are present on the market and their degree of bioavailability differs depending on the form of magnesium salt used. Aquamin-Mg is a natural source of magnesium, containing 72 additional trace minerals derived from the clean waters off the Irish coast. However, the in vitro bioaccessibility and bioavailability of Aquamin-Mg in comparison with other supplement sources of magnesium has yet to be tested. Method: Aquamin-Mg, magnesium chloride (MgCl2) and magnesium oxide (MgO) were subjected to gastrointestinal digestion according to the harmonized INFOGEST in vitro digestion method and in vitro bioavailability tested using the Caco-2 cell model. Magnesium concentration was measured by atomic absorption spectrophotometry (AAS). Results: Magnesium recovery from both Aquamin-Mg and MgCl2 was greater than for MgO. Magnesium from all three sources was transported across the epithelial monolayer with Aquamin-Mg displaying a comparable profile to the more bioavailable MgCl2. Conclusions: Our data support that magnesium derived from a marine-derived multimineral product is bioavailable to a significantly greater degree than MgO and displays a similar profile to the more bioavailable MgCl2 and may offer additional health benefits given its multimineral profile. View Full-Text
A printed edition of this Special Issue is available here.
Share & Cite This Article
Felice, V.D.; O’Gorman, D.M.; O’Brien, N.M.; Hyland, N.P. Bioaccessibility and Bioavailability of a Marine-Derived Multimineral, Aquamin-Magnesium. Nutrients 2018, 10, 912.
Felice VD, O’Gorman DM, O’Brien NM, Hyland NP. Bioaccessibility and Bioavailability of a Marine-Derived Multimineral, Aquamin-Magnesium. Nutrients. 2018; 10(7):912.Chicago/Turabian Style
Felice, Valeria D.; O’Gorman, Denise M.; O’Brien, Nora M.; Hyland, Niall P. 2018. "Bioaccessibility and Bioavailability of a Marine-Derived Multimineral, Aquamin-Magnesium." Nutrients 10, no. 7: 912.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.