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How Healthy Lifestyle Factors at Midlife Relate to Healthy Aging

Nutritional Epidemiology Research Team (EREN), Epidemiology and Statistics Research Center, U1153 National Institute of Health and Medical Research (INSERM), U1125 National Institute for Agricultural Research (INRA), National Conservatory of Arts and Crafts (CNAM), Paris 13 University, Sorbonne Paris Cité COMUE, F-93017 Bobigny, France
AP-HP, Diagnosis and Therapeutic Center, Faculty of Medicine, Hôtel-Dieu Hospital, Paris-Descartes University, F-75004 Paris, France
Département de Santé Publique, Hôpital Avicenne, F-93017 Bobigny, France
Author to whom correspondence should be addressed.
Nutrients 2018, 10(7), 854;
Received: 2 June 2018 / Revised: 20 June 2018 / Accepted: 26 June 2018 / Published: 30 June 2018
With increasing life expectancies worldwide, it is an important public health issue to identify factors that influence the quality of aging. We aimed to investigate the individual and combined roles of lifestyle factors at midlife for healthy aging (HA). We analyzed data from 2203 participants of the French ”Supplémentation en Vitamines et Minéraux Antioxydants” (SU.VI.MAX) cohort aged 45–60 years at baseline (1994–1995), and assessed the combined impact of lifestyle factors (weight, smoking status, physical activity, alcohol consumption, and diet) on HA (absence of chronic diseases and function-limiting pain, good physical and cognitive functioning, functional independence, no depressive symptoms, and good social and self-perceived health) with a five-component healthy lifestyle index (HLI). Relative risks (RR) and 95% confidence intervals (CIs) were estimated using a robust-error-variance Poisson regression. Approximately 39% of our sample aged healthily. After adjustment for potential confounders, a one-point increase in HLI was related to an 11% higher probability of HA (95% CI = 6%, 16%; p < 0.001). The proportions of HA attributable to specific factors based on the “population attributable risk” concept were 7.6%, 6.0%, 7.8%, and 16.5% for body mass index (BMI), physical activity, diet quality, and smoking status, respectively. This study highlights the importance of healthy lifestyle habits at midlife for the promotion of good overall health during aging. View Full-Text
Keywords: smoking; diet; physical activity; alcohol smoking; diet; physical activity; alcohol
MDPI and ACS Style

Atallah, N.; Adjibade, M.; Lelong, H.; Hercberg, S.; Galan, P.; Assmann, K.E.; Kesse-Guyot, E. How Healthy Lifestyle Factors at Midlife Relate to Healthy Aging. Nutrients 2018, 10, 854.

AMA Style

Atallah N, Adjibade M, Lelong H, Hercberg S, Galan P, Assmann KE, Kesse-Guyot E. How Healthy Lifestyle Factors at Midlife Relate to Healthy Aging. Nutrients. 2018; 10(7):854.

Chicago/Turabian Style

Atallah, Nathalie, Moufidath Adjibade, Hélène Lelong, Serge Hercberg, Pilar Galan, Karen E. Assmann, and Emmanuelle Kesse-Guyot. 2018. "How Healthy Lifestyle Factors at Midlife Relate to Healthy Aging" Nutrients 10, no. 7: 854.

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