Next Article in Journal
Association between the Portion Sizes of Traditional Japanese Seasonings—Soy Sauce and Miso—and Blood Pressure: Cross-Sectional Study Using National Health and Nutrition Survey, 2012–2016 Data
Next Article in Special Issue
Quality of Dietary Fat Intake and Body Weight and Obesity in a Mediterranean Population: Secondary Analyses within the PREDIMED Trial
Previous Article in Journal
Magnesium: Are We Consuming Enough?
Previous Article in Special Issue
Genome-Wide Association Studies of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue in Elderly Individuals: Associations with Insulin Sensitivity
Article Menu
Issue 12 (December) cover image

Export Article

Open AccessReview

The Role of Omega-3 Fatty Acids in the Setting of Coronary Artery Disease and COPD: A Review

1
Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria
2
Department of Urology, Klinikum rechts der Isar, Technische Universität München, 81675 Munich, Germany
*
Author to whom correspondence should be addressed.
Authors with equal contribution.
Nutrients 2018, 10(12), 1864; https://doi.org/10.3390/nu10121864
Received: 11 October 2018 / Revised: 9 November 2018 / Accepted: 22 November 2018 / Published: 2 December 2018
(This article belongs to the Special Issue Fatty Acids and Cardiometabolic Health)
  |  
PDF [1057 KB, uploaded 2 December 2018]
  |  

Abstract

Chronic obstructive pulmonary disease (COPD) is a growing healthcare concern and will represent the third leading cause of death worldwide within the next decade. COPD is the result of a complex interaction between environmental factors, especially cigarette smoking, air pollution, and genetic preconditions, which result in persistent inflammation of the airways. There is growing evidence that the chronic inflammatory state, measurable by increased levels of circulating cytokines, chemokines, and acute phase proteins, may not be confined to the lungs. Cardiovascular disease (CVD) and especially coronary artery disease (CAD) are common comorbidities of COPD, and low-grade systemic inflammation plays a decisive role in its pathogenesis. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) exert multiple functions in humans and are crucially involved in limiting and resolving inflammatory processes. n-3 PUFAs have been intensively studied for their ability to improve morbidity and mortality in patients with CVD and CAD. This review aims to summarize the current knowledge on the effects of n-3 PUFA on inflammation and its impact on CAD in COPD from a clinical perspective. View Full-Text
Keywords: omega 3; PUFA; n-3 PUFA; COPD; inflammation; coronary artery disease; ischemic heart disease; CAD; CHD omega 3; PUFA; n-3 PUFA; COPD; inflammation; coronary artery disease; ischemic heart disease; CAD; CHD
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed
Printed Edition Available!
A printed edition of this Special Issue is available here.

Share & Cite This Article

MDPI and ACS Style

Pizzini, A.; Lunger, L.; Sonnweber, T.; Weiss, G.; Tancevski, I. The Role of Omega-3 Fatty Acids in the Setting of Coronary Artery Disease and COPD: A Review. Nutrients 2018, 10, 1864.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top