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Nutrients 2018, 10(12), 1836;

Probiotics on Pediatric Functional Gastrointestinal Disorders

Department of Pediatrics, University of Turku, 20521 Turku, Finland
Department of Pediatrics and Adolescent Medicine, Turku University Hospital, 20521 Turku, Finland
Author to whom correspondence should be addressed.
Received: 26 October 2018 / Revised: 22 November 2018 / Accepted: 27 November 2018 / Published: 29 November 2018
(This article belongs to the Special Issue Probiotics and Prebiotics in Pediatrics)
Full-Text   |   PDF [276 KB, uploaded 29 November 2018]


The potential association between gut microbiota perturbations and childhood functional gastrointestinal disturbances opens interesting therapeutic and preventive possibilities with probiotics. The aim of this review was to evaluate current evidence on the efficacy of probiotics for the management of pediatric functional abdominal pain disorders, functional constipation and infantile colic. Thus far, no single strain, combination of strains or synbiotics can be recommended for the management of irritable bowel syndrome, functional abdominal pain or functional constipation in children. However, Lactobacillus reuteri DSM 17938 may be considered for the management of breastfed colic infants, while data on other probiotic strains, probiotic mixtures or synbiotics are limited in infantile colic. View Full-Text
Keywords: probiotics; functional gastrointestinal disorders; functional abdominal pain disorders; functional constipation; infantile colic probiotics; functional gastrointestinal disorders; functional abdominal pain disorders; functional constipation; infantile colic
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Pärtty, A.; Rautava, S.; Kalliomäki, M. Probiotics on Pediatric Functional Gastrointestinal Disorders. Nutrients 2018, 10, 1836.

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