Digestive Responses to Fortified Cow or Goat Dairy Drinks: A Randomised Controlled Trial
AbstractFortified milk drinks are predominantly manufactured from bovine (cow) sources. Alternative formulations include those prepared with hydrolysed bovine milk proteins or from alternate bovidae species, such as caprine (goat) milk. Currently, there is little data on protein digestive and metabolic responses following ingestion of fortified milk drinks. To examine the digestive and metabolic responses to commercially-available fortified milks, young adults (n = 15 males: 15 females), in a randomised sequence, ingested isonitrogenous quantities of whole cow-protein (WC), whole goat-protein (WG), or partially-hydrolysed whey cow-protein (HC), commercial fortified milks. Plasma amino acid (AA) and hormonal responses were measured at baseline and again at 5 h after ingestion. Paracetamol recovery, breath hydrogen, and subjective digestive responses were also measured. Postprandial plasma AA was similar between WC and WG, while AA appearance was suppressed with HC. Following HC, there was a negative incremental AUC in plasma branched-chain AAs. Further, HC had delayed gastric emptying, increased transit time, and led to exaggerated insulin and GLP-1 responses, in comparison to whole protein formulas. Overall, WC and WG had similar protein and digestive responses with no differences in digestive comfort. Contrastingly, HC led to delayed gastric emptying, attenuated AA appearance, and a heightened circulating insulin response. View Full-Text
Share & Cite This Article
Milan, A.M.; Hodgkinson, A.J.; Mitchell, S.M.; Prodhan, U.K.; Prosser, C.G.; Carpenter, E.A.; Fraser, K.; Cameron-Smith, D. Digestive Responses to Fortified Cow or Goat Dairy Drinks: A Randomised Controlled Trial. Nutrients 2018, 10, 1492.
Milan AM, Hodgkinson AJ, Mitchell SM, Prodhan UK, Prosser CG, Carpenter EA, Fraser K, Cameron-Smith D. Digestive Responses to Fortified Cow or Goat Dairy Drinks: A Randomised Controlled Trial. Nutrients. 2018; 10(10):1492.Chicago/Turabian Style
Milan, Amber M.; Hodgkinson, Alison J.; Mitchell, Sarah M.; Prodhan, Utpal K.; Prosser, Colin G.; Carpenter, Elizabeth A.; Fraser, Karl; Cameron-Smith, David. 2018. "Digestive Responses to Fortified Cow or Goat Dairy Drinks: A Randomised Controlled Trial." Nutrients 10, no. 10: 1492.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.