The Significance of Low Titre Antigliadin Antibodies in the Diagnosis of Gluten Ataxia
Abstract
:1. Introduction
2. Methods
2.1. AGA Serological Testing
2.2. Patient Selection and Follow-up
2.3. MR Spectroscopy
2.4. Statistical Analysis
3. Results
4. Discussion
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Dietary Status in GA Groups | Numb per Group | Mean Age | Mean Duration of Ataxia in Years | Mean MR Spectroscopy Change from Baseline (NAA/Cr Area Ratio) | Numb Improv-ed | Mean AGA Antibody Titre at Baseline (SD) | Mean AGA Antibody Titre at the Time of 2nd Scan (SD) |
---|---|---|---|---|---|---|---|
strict GFD | 10 | 65 | 6.4 | +0.092 | 10 | 3.6 (0.46) | 1.8 (0.74) |
partial GFD | 5 | 50 | 6.6 | −0.028 | 1 | 4.5 (1.3) | 3.8 (1) |
not on diet | 6 | 77 | 7.3 | −0.098 | 0 | 4.2 (1.3) | 4.2 (1.8) |
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Hadjivassiliou, M.; Grünewald, R.A.; Sanders, D.S.; Zis, P.; Croall, I.; Shanmugarajah, P.D.; Sarrigiannis, P.G.; Trott, N.; Wild, G.; Hoggard, N. The Significance of Low Titre Antigliadin Antibodies in the Diagnosis of Gluten Ataxia. Nutrients 2018, 10, 1444. https://doi.org/10.3390/nu10101444
Hadjivassiliou M, Grünewald RA, Sanders DS, Zis P, Croall I, Shanmugarajah PD, Sarrigiannis PG, Trott N, Wild G, Hoggard N. The Significance of Low Titre Antigliadin Antibodies in the Diagnosis of Gluten Ataxia. Nutrients. 2018; 10(10):1444. https://doi.org/10.3390/nu10101444
Chicago/Turabian StyleHadjivassiliou, Marios, Richard A Grünewald, David S Sanders, Panagiotis Zis, Iain Croall, Priya D Shanmugarajah, Ptolemaios G Sarrigiannis, Nick Trott, Graeme Wild, and Nigel Hoggard. 2018. "The Significance of Low Titre Antigliadin Antibodies in the Diagnosis of Gluten Ataxia" Nutrients 10, no. 10: 1444. https://doi.org/10.3390/nu10101444
APA StyleHadjivassiliou, M., Grünewald, R. A., Sanders, D. S., Zis, P., Croall, I., Shanmugarajah, P. D., Sarrigiannis, P. G., Trott, N., Wild, G., & Hoggard, N. (2018). The Significance of Low Titre Antigliadin Antibodies in the Diagnosis of Gluten Ataxia. Nutrients, 10(10), 1444. https://doi.org/10.3390/nu10101444