Anti-Aging Effects of Terminalia bellirica, Phyllanthus emblica, Triphala, and Carica papaya Extracts for Sustainable Youth

Round 1

Reviewer 1 Report

The study is carried out correctly.

The topic is very interestiong.

The layout is compatible with the editorial requirements.

Please add the study limitations in the text!

 

 

Author Response

Thanks for the reviewer comments on the paper. The limitations of the study have been supplemented as follows.

4. Discussion and Conclusions

These results suggest that galvaghera, Phyllanthus emblema, Triphala and Carica papaya extracts increase collagen and elastin synthesis, potentially inhibiting damage to skin binding cells by aging. However, despite these meaningful research results, this study had limitations in not being able to apply clinical trials or animal test models. Subsequent studies need to be conducted on whitening and the establishment of functional mechanisms and surface components for whitening and crease improvement extracts for galvaghera, Phyllanthus emblica, Triphala and Carica papaya and animal models experiments, which can lead to the development of a safe natural material for whitening and wrinkle improvement.

 

Author Response File: Author Response.docx

Reviewer 2 Report

English should be GREATLY improved and article rewritten

Author Response

Thanks for the reviewer comments on the paper.

English corrections were made for the entire thesis. I am attaching the thesis because I have proofread all the parts.

 

Author Response File: Author Response.docx

Round 2

Reviewer 2 Report

What is "subcutaneous epidermis" (line 38)?  Sentences like the second one in the abstract are unclear and difficult to read.  There are even incomplete sentences (Line 323). I think the authors should read carefully the article before resubmitting it again.

Author Response

Thanks for the reviewer Comments.

The comments have been corrected and supplemented as follows.

thank you.

 

What is "subcutaneous epidermis" (line 38)?  

There was an error in the English notation, the correct spelling is epidermis. This part has been modified with epidermis.

(before) subcutaneous epidermis

(after) epidermis

 

Sentences like the second one in the abstract are unclear and difficult to read.  

This part has been modified as follows to make the meaning more clear.

(before) However, excessive management can cause side effects and has disadvantages that they are only short-term effects. 

(after) However, managing external beauty has the disadvantage of causing side effects or that the effect does not last. 

 

There are even incomplete sentences (Line 323). 

Incomplete sentences have been corrected as follows.

In the dermal tissue of the skin, collagen and elastinform a network structure and maintain the elasticity of the skin. However, collagen and elastin are broken by collagenase and elastase in their networkstructure, which is the main cause of wrinkles [23,24]. 

 

I think the authors should read carefully the article before resubmitting it again.

I reviewed the contents of the thesis as a whole and corrected any typos or awkward sentences.

Author Response File: Author Response.docx

Round 3

Reviewer 2 Report

The article has been greatly improved