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Clinics and Practice
Volume 2
Issue 3
10.4081/cp.2012.e74
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Clinics and Practice is published by MDPI from Volume 11 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

Use of Therapeutic Surfactant Lavage in a Preterm Infant with Massive Pulmonary Hemorrhage

by
Ino Kanavaki
1,*,
Laszlo Vutskits
2 and
Peter C. Rimensberger
1
1
Pediatric and Neonatal Intensive Care Unit, Department of Pediatrics, University Hospital of Geneva, Switzerland
2
Department of Anaesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Switzerland
*
Author to whom correspondence should be addressed.
Clin. Pract. 2012, 2(3), e74; https://doi.org/10.4081/cp.2012.e74
Submission received: 26 October 2011 / Revised: 28 June 2012 / Accepted: 8 July 2012 / Published: 6 August 2012

Abstract

We report a case of a premature infant presenting with recurrent pulmonary hemorrhage in which we performed a therapeutic lavage with diluted surfactant after an acute episode of bleeding with severe intractable hypoxemia. Repeated small aliquots of diluted surfactant (10x2 mL) allowed rapid improvement in oxygenation and reduction of required mean airway pressures during high frequency oscillatory ventilation. This observation may suggest that surfactant lavage could be beneficial in massive pulmonary hemorrhage in infants. A randomized controlled trial might be needed to clarify the potential benefit of this therapeutic intervention on outcome of infants suffering from this life-threatening complication.
Keywords: pulmonary hemorrhage; surfactant lavage; prematurity pulmonary hemorrhage; surfactant lavage; prematurity

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MDPI and ACS Style

Kanavaki, I.; Vutskits, L.; Rimensberger, P.C. Use of Therapeutic Surfactant Lavage in a Preterm Infant with Massive Pulmonary Hemorrhage. Clin. Pract. 2012, 2, e74. https://doi.org/10.4081/cp.2012.e74

AMA Style

Kanavaki I, Vutskits L, Rimensberger PC. Use of Therapeutic Surfactant Lavage in a Preterm Infant with Massive Pulmonary Hemorrhage. Clinics and Practice. 2012; 2(3):e74. https://doi.org/10.4081/cp.2012.e74

Chicago/Turabian Style

Kanavaki, Ino, Laszlo Vutskits, and Peter C. Rimensberger. 2012. "Use of Therapeutic Surfactant Lavage in a Preterm Infant with Massive Pulmonary Hemorrhage" Clinics and Practice 2, no. 3: e74. https://doi.org/10.4081/cp.2012.e74

APA Style

Kanavaki, I., Vutskits, L., & Rimensberger, P. C. (2012). Use of Therapeutic Surfactant Lavage in a Preterm Infant with Massive Pulmonary Hemorrhage. Clinics and Practice, 2(3), e74. https://doi.org/10.4081/cp.2012.e74

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