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Thalassemia Reports
Volume 4
Issue 1
10.4081/thal.2014.2152
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Thalassemia Reports is published by MDPI from Volume 12 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Article

Profile of Hemoglobin D Trait in West Bengal, India

by
Tuphan K. Dolai
1,*,
Rajkumar Bera
2,
Suman K. Maji
1 and
Prakas K. Mandal
3
1
Hematology Department, NRS Medical College and Hospital, Kolkata, India
2
Thalassaemia Society of Midnapur District, West Bengal, India
3
Pathology Department, IPGMER, Kolkata, India
*
Author to whom correspondence should be addressed.
Thalass. Rep. 2014, 4(1), 2152; https://doi.org/10.4081/thal.2014.2152
Submission received: 23 November 2013 / Revised: 21 March 2014 / Accepted: 21 March 2014 / Published: 7 April 2014

Abstract

Hemoglobin (Hb) D Punjab is one of the most commonly observed abnormal hemoglobinopathy worldwide. There was no systematic large published study to investigate the characteristic of Hb D Punjab trait in India. This study was conducted in school and college students, newly married couples and pregnant women after proper counseling in the rural areas of West Bengal state in eastern India. Complete blood count was done by Sysmax Automated Hematology Analyzer KX 21 (Sysmex Corp., Kobe, Japan) and thalassemia testing was done using high-performance liquid chromatography (Variant TM - Bio-Rad Lab., Hercules, CA, USA). A total of 46,139 individuals were screened for hemoglobinopathies. Hb D trait was found in 0.35%. Hypochromia rather than microcytosis is consistent finding in Hb D trait. Anisocytosis is absent in Hb D trait. In almost all (99.37%) cases, Hb D is within 40% of total hemoglobin. This data is likely to be helpful for screening of hemoglobinopathy in resource poor setting.
Keywords: hemoglobin D trait; red blood cell indices; high-performance liquid chromatography hemoglobin D trait; red blood cell indices; high-performance liquid chromatography

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MDPI and ACS Style

Dolai, T.K.; Bera, R.; Maji, S.K.; Mandal, P.K. Profile of Hemoglobin D Trait in West Bengal, India. Thalass. Rep. 2014, 4, 2152. https://doi.org/10.4081/thal.2014.2152

AMA Style

Dolai TK, Bera R, Maji SK, Mandal PK. Profile of Hemoglobin D Trait in West Bengal, India. Thalassemia Reports. 2014; 4(1):2152. https://doi.org/10.4081/thal.2014.2152

Chicago/Turabian Style

Dolai, Tuphan K., Rajkumar Bera, Suman K. Maji, and Prakas K. Mandal. 2014. "Profile of Hemoglobin D Trait in West Bengal, India" Thalassemia Reports 4, no. 1: 2152. https://doi.org/10.4081/thal.2014.2152

APA Style

Dolai, T. K., Bera, R., Maji, S. K., & Mandal, P. K. (2014). Profile of Hemoglobin D Trait in West Bengal, India. Thalassemia Reports, 4(1), 2152. https://doi.org/10.4081/thal.2014.2152

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