A Facile Synthesis of Flower-like Iron Oxide Nanoparticles and Its Efficacy Measurements for Antibacterial, Cytotoxicity and Antioxidant Activity
Abstract
:1. Introduction
2. Materials and Methods
2.1. Chemicals and Reagents
2.2. Synthesis of Fe2O3 Nanoparticles
2.3. Instrumentation
2.4. Evaluation of the Cytotoxic Activity of Fe2O3 Nanoparticles
2.4.1. Cell Culture
2.4.2. MTT Assay
2.5. Antibacterial Activity of Fe2O3 Nanoparticles
2.6. Antioxidant Activity of Fe2O3 Nanoparticles
2.7. Statistical Analysis
3. Results and Discussion
3.1. Physicochemical Characterization of Fe2O3 Nanoparticles
3.2. Morphology and Elemental Mapping of Fe2O3 Nanoparticles
3.3. In Vitro Cytotoxicity Assay of Fe2O3 Nanoparticles
3.4. In Vitro Antibacterial Assessment of Fe2O3 Nanoparticles
3.5. Antioxidant Efficiency of Fe2O3 Nanoparticles: A Possible Mechanism of Action for Antibacterial and Cytotoxic Activity
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Concentration (µg/mL) | * Zone of Inhibition (mm) Mean ± SD | ||
---|---|---|---|
S. aureus | K. pneumoniae | E. coli | |
Control | 5 | 5 | 5 |
10 | 8.3 ± 0.4 | 8.4 ± 0.4 | 10.4 ± 0.5 |
20 | 10.2 ± 0.2 | 10.1 ± 0.1 | 14.1 ± 0.1 |
30 | 14.4 ± 0.3 | 13.4 ± 0.4 | 16.3 ± 0.3 |
40 | 16.2 ± 0.2 | 17.2 ± 0.2 | 19.3 ± 0.3 |
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Tabassum, N.; Singh, V.; Chaturvedi, V.K.; Vamanu, E.; Singh, M.P. A Facile Synthesis of Flower-like Iron Oxide Nanoparticles and Its Efficacy Measurements for Antibacterial, Cytotoxicity and Antioxidant Activity. Pharmaceutics 2023, 15, 1726. https://doi.org/10.3390/pharmaceutics15061726
Tabassum N, Singh V, Chaturvedi VK, Vamanu E, Singh MP. A Facile Synthesis of Flower-like Iron Oxide Nanoparticles and Its Efficacy Measurements for Antibacterial, Cytotoxicity and Antioxidant Activity. Pharmaceutics. 2023; 15(6):1726. https://doi.org/10.3390/pharmaceutics15061726
Chicago/Turabian StyleTabassum, Nazish, Virendra Singh, Vivek K. Chaturvedi, Emanuel Vamanu, and Mohan P. Singh. 2023. "A Facile Synthesis of Flower-like Iron Oxide Nanoparticles and Its Efficacy Measurements for Antibacterial, Cytotoxicity and Antioxidant Activity" Pharmaceutics 15, no. 6: 1726. https://doi.org/10.3390/pharmaceutics15061726