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Penetration Enhancers in Ocular Drug Delivery
Open AccessEditorial

Transmucosal Absorption Enhancers in the Drug Delivery Field

1
School of Pharmacy, Royal College of Surgeons in Ireland, St. Stephens Green, Dublin 2, Ireland
2
Department of Biomolecular Sciences, University of Urbino Carlo Bo, Piazza del Rinascimento 6, 61029 Urbino (PU), Italy
3
IDentity, 19 Cavendish Crescent North, The Park, Nottingham NG7 1BA, UK
*
Authors to whom correspondence should be addressed.
Pharmaceutics 2019, 11(7), 339; https://doi.org/10.3390/pharmaceutics11070339
Received: 10 July 2019 / Accepted: 11 July 2019 / Published: 15 July 2019
(This article belongs to the Special Issue Transmucosal Absorption Enhancers in the Drug Delivery Field)
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PDF [244 KB, uploaded 17 July 2019]

Abstract

Drug delivery systems that safely and consistently improve transport of poorly absorbed compounds across epithelial barriers are highly sought within the drug delivery field. The use of chemical permeation enhancers is one of the simplest and widely tested approaches to improve transmucosal permeability via oral, nasal, buccal, ocular and pulmonary routes. To date, only a small number of permeation enhancers have progressed to clinical trials, and only one product that includes a permeation enhancer has reached the pharmaceutical market. This editorial is an introduction to the special issue entitled Transmucosal Absorption Enhancers in the Drug Delivery Field (https://www.mdpi.com/journal/pharmaceutics/special_issues/transmucosal_absorption_enhancers). The guest editors outline the scope of the issue, reflect on the results and the conclusions of the 19 articles published in the issue and provide an outlook on the use of permeation enhancers in the drug delivery field. View Full-Text
Keywords: permeation enhancers; absorption modifying excipients; oral delivery; nasal delivery; ocular delivery; vaginal delivery; transmucosal permeation permeation enhancers; absorption modifying excipients; oral delivery; nasal delivery; ocular delivery; vaginal delivery; transmucosal permeation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Maher, S.; Casettari, L.; Illum, L. Transmucosal Absorption Enhancers in the Drug Delivery Field. Pharmaceutics 2019, 11, 339.

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