Next Article in Journal
A Truncated Nef Peptide from SIVcpz Inhibits the Production of HIV-1 Infectious Progeny
Next Article in Special Issue
Clomiphene and Its Isomers Block Ebola Virus Particle Entry and Infection with Similar Potency: Potential Therapeutic Implications
Previous Article in Journal
Recombinant Ranaviruses for Studying Evolution of Host–Pathogen Interactions in Ectothermic Vertebrates
Previous Article in Special Issue
Aerosol Transmission of Filoviruses
Erratum published on 4 August 2016, see Viruses 2016, 8(8), 217.
Open AccessArticle

Effectiveness of Four Disinfectants against Ebola Virus on Different Materials

CBR Division, Defence Science and Technology Laboratory (Dstl), Room 201, Building 7a. Dstl, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK
MIG-CCHS2/C2, 1710 Naval Air Squadron, Room 104c, Unicorn House, Yeovilton BA22 8HW, UK
Author to whom correspondence should be addressed.
Academic Editor: Jens H. Kuhn
Viruses 2016, 8(7), 185;
Received: 25 April 2016 / Revised: 20 June 2016 / Accepted: 24 June 2016 / Published: 7 July 2016
(This article belongs to the Collection Advances in Ebolavirus, Marburgvirus, and Cuevavirus Research)
The West Africa Ebola virus (EBOV) outbreak has highlighted the need for effective disinfectants capable of reducing viral load in a range of sample types, equipment and settings. Although chlorine-based products are widely used, they can also be damaging to equipment or apparatus that needs continuous use such as aircraft use for transportation of infected people. Two aircraft cleaning solutions were assessed alongside two common laboratory disinfectants in a contact kill assay with EBOV on two aircraft relevant materials representative of a porous and non-porous surface. A decimal log reduction of viral titre of 4 is required for a disinfectant to be deemed effective and two of the disinfectants fulfilled this criteria under the conditions tested. One product, Ardrox 6092, was found to perform similarly to sodium hypochlorite, but as it does not have the corrosive properties of sodium hypochlorite, it could be an alternative disinfectant solution to be used for decontamination of EBOV on sensitive apparatus. View Full-Text
Keywords: Ebola virus; disinfection; decontamination; inactivation; sodium hypochlorite; safety Ebola virus; disinfection; decontamination; inactivation; sodium hypochlorite; safety
Show Figures

Figure 1

MDPI and ACS Style

Smither, S.; Phelps, A.; Eastaugh, L.; Ngugi, S.; O’Brien, L.; Dutch, A.; Lever, M.S. Effectiveness of Four Disinfectants against Ebola Virus on Different Materials. Viruses 2016, 8, 185.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Search more from Scilit
Back to TopTop