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Zoonotic Hepatitis E Virus: Classification, Animal Reservoirs and Transmission Routes

1
French Agency for Food, Environmental and Occupational Health & Safety (ANSES), Animal Health Laboratory, UMR (joint research unit) 1161 Virology, 94701 Maisons-Alfort, France
2
French National Institute for Agricultural Research (INRA), UMR (joint research unit) 1161 Virology, 94700 Maisons-Alfort, France
3
Association of Universities and High Education Institutions (ComUE), Paris-Est Créteil Val-de-Marne University, National Veterinary School, UMR (joint research unit) 1161 Virology, 94700 Maisons-Alfort, France
*
Author to whom correspondence should be addressed.
Viruses 2016, 8(10), 270; https://doi.org/10.3390/v8100270
Received: 22 July 2016 / Accepted: 22 September 2016 / Published: 3 October 2016
(This article belongs to the Special Issue Recent Progress in Hepatitis E Virus Research)
During the past ten years, several new hepatitis E viruses (HEVs) have been identified in various animal species. In parallel, the number of reports of autochthonous hepatitis E in Western countries has increased as well, raising the question of what role these possible animal reservoirs play in human infections. The aim of this review is to present the recent discoveries of animal HEVs and their classification within the Hepeviridae family, their zoonotic and species barrier crossing potential, and possible use as models to study hepatitis E pathogenesis. Lastly, this review describes the transmission pathways identified from animal sources. View Full-Text
Keywords: hepatitis E virus (HEV); animals; zoonotic reservoir; foodborne transmission hepatitis E virus (HEV); animals; zoonotic reservoir; foodborne transmission
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MDPI and ACS Style

Doceul, V.; Bagdassarian, E.; Demange, A.; Pavio, N. Zoonotic Hepatitis E Virus: Classification, Animal Reservoirs and Transmission Routes. Viruses 2016, 8, 270.

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