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Case Report

Managing HIV-Associated Hodgkin Lymphoma During the COVID-19 Pandemic: Case Report and Literature Review

by
Monica-Daniela Padurariu-Covit
1,2,
Mihaela Andreescu
3,4,
Elena Niculet
5,6,
Alina Plesea-Condratovici
7,* and
Manuela Arbune
8,9
1
Doctoral School of Biomedical Sciences, Dunarea de Jos University of Galati, 800008 Galati, Romania
2
Hematology Department, Emergency County Hospital Sf. Apostol Andrei, 800578 Galati, Romania
3
Faculty of Medicine, Titu Maiorescu University, 031593 Bucharest, Romania
4
Hematology Department, Colentina Clinical Hospital, 020125 Bucharest, Romania
5
Morphological and Functional Sciences Department, Faculty of Medicine and Pharmacy, Dunarea de Jos University of Galati, 800008 Galati, Romania
6
Morphological Department, Emergency County Hospital Sf. Apostol Andrei, 800578 Galati, Romania
7
Medical Department, Medicine and Pharmacy Faculty, Dunarea de Jos University of Galati, 800008 Galati, Romania
8
Clinical Medical Department, Dunarea de Jos University of Galati, 800008 Galati, Romania
9
Infectious Diseases Clinic Hospital Sf. Cuv. Parascheva, 800179 Galati, Romania
*
Author to whom correspondence should be addressed.
Viruses 2025, 17(3), 404; https://doi.org/10.3390/v17030404
Submission received: 19 February 2025 / Revised: 7 March 2025 / Accepted: 11 March 2025 / Published: 12 March 2025
(This article belongs to the Special Issue Viral Infections in Special Populations)

Abstract

The COVID-19 pandemic delayed the consultation of many patients with specialists. We present the case of a 57-year-old patient with HIV infection, COVID-19 pneumonia, and Hodgkin lymphoma. Discordant immunohistochemistry results from biopsy samples delayed the hematological diagnosis and initiation of oncological therapy. The late diagnosis of HIV infection at the stage of severe immunosuppression, along with advanced Hodgkin lymphoma and COVID-19 co-infection, represents a complex pathogenic triad that is challenging to manage. Healthcare-associated COVID-19 infections pose a significant risk during the pandemic for chronic patients requiring frequent hospital visits.
Keywords: HIV; Hodgkin lymphoma; COVID-19; late presenter; acquired immunodeficiency HIV; Hodgkin lymphoma; COVID-19; late presenter; acquired immunodeficiency

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MDPI and ACS Style

Padurariu-Covit, M.-D.; Andreescu, M.; Niculet, E.; Plesea-Condratovici, A.; Arbune, M. Managing HIV-Associated Hodgkin Lymphoma During the COVID-19 Pandemic: Case Report and Literature Review. Viruses 2025, 17, 404. https://doi.org/10.3390/v17030404

AMA Style

Padurariu-Covit M-D, Andreescu M, Niculet E, Plesea-Condratovici A, Arbune M. Managing HIV-Associated Hodgkin Lymphoma During the COVID-19 Pandemic: Case Report and Literature Review. Viruses. 2025; 17(3):404. https://doi.org/10.3390/v17030404

Chicago/Turabian Style

Padurariu-Covit, Monica-Daniela, Mihaela Andreescu, Elena Niculet, Alina Plesea-Condratovici, and Manuela Arbune. 2025. "Managing HIV-Associated Hodgkin Lymphoma During the COVID-19 Pandemic: Case Report and Literature Review" Viruses 17, no. 3: 404. https://doi.org/10.3390/v17030404

APA Style

Padurariu-Covit, M.-D., Andreescu, M., Niculet, E., Plesea-Condratovici, A., & Arbune, M. (2025). Managing HIV-Associated Hodgkin Lymphoma During the COVID-19 Pandemic: Case Report and Literature Review. Viruses, 17(3), 404. https://doi.org/10.3390/v17030404

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