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Review

The Role of Serology Testing in the Context of Immunization Policies for COVID-19 in Latin American Countries

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Clinical Pathology, Hospital Israelita Albert Einstein, São Paulo 05652-900, Brazil
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Microbiology Sector, Federal University of São Paulo’s Central Laboratory Activities, São Paulo 04088-002, Brazil
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Brazilian Society of Clinical Pathology and Laboratory Medicine, Rio de Janeiro 22220-040, Brazil
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National Institute of Public Health, Cuernavaca 62100, Mexico
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Infectious Diseases Division, Federal University of Sao Paulo, São Paulo 04039-032, Brazil
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Department of Medicine, Hospital de Niños Gutiérrez, Buenos Aires C1425-EFD, Argentina
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Pediatric Infectious Diseases Program, Faculty of Medicine, University of Buenos Aires, Buenos Aires C1121-ABG, Argentina
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Pediatrics and Vaccinology, Faculty of Medicine, University of Salvador, Buenos Aires C1055-AAG, Argentina
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Policy Wisdom LLC, Miami, FL 33173, USA
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Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago de Chile 8380000, Chile
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Millennium Institute of Immunology and Immunotherapy, University of Chile, Santiago de Chile 8331150, Chile
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Chilean Academy of Medicine, Santiago de Chile 6500445, Chile
*
Author to whom correspondence should be addressed.
Academic Editors: Eurico Arruda, José Luiz Proença Módena, William Marciel de Souza and Helena Lage Ferreira
Viruses 2021, 13(12), 2391; https://doi.org/10.3390/v13122391
Received: 30 September 2021 / Revised: 18 November 2021 / Accepted: 18 November 2021 / Published: 29 November 2021
(This article belongs to the Special Issue SARS-CoV-2 and COVID-19 in Latin America)
This review aims to explore the role and value of serology testing in the context of COVID-19 immunization policies in Latin American countries and the barriers and challenges to the adequate use and uptake of this tool. It builds on a review of the academic literature, evidence, and existing policies, and includes a multistage process of discussion and feedback by a group of five experts. Regional and country-level evidence and resources from five focus countries—Argentina, Brazil, Chile, Colombia, and Mexico—were collected and analyzed. This review contains an overview of (1) the impact of the SARS-CoV-2 pandemic, the variants of concern and current testing strategies, (2) the introduction of COVID-19 vaccination, (3) the potential use of serology testing to support immunization initiatives, (4) the current frameworks for the use of serology testing in the region, and (5) the barriers and challenges to implementing serology testing in the context of COVID-19 immunization policies, including a discussion on the potential actions required to address these barriers and facilitate the uptake of this strategy in the region. Stakeholders can use elements of this document to guide timely decision-making, raise awareness, and inspire further studies. View Full-Text
Keywords: COVID-19; SARS-CoV-2; pandemic; serology tests; antibody tests; diagnostic tests; health policy; immunization; vaccination; Latin America COVID-19; SARS-CoV-2; pandemic; serology tests; antibody tests; diagnostic tests; health policy; immunization; vaccination; Latin America
MDPI and ACS Style

dos Santos Ferreira, C.E.; Gómez-Dantés, H.; Junqueira Bellei, N.C.; López, E.; Nogales Crespo, K.A.; O’Ryan, M.; Villegas, J. The Role of Serology Testing in the Context of Immunization Policies for COVID-19 in Latin American Countries. Viruses 2021, 13, 2391. https://doi.org/10.3390/v13122391

AMA Style

dos Santos Ferreira CE, Gómez-Dantés H, Junqueira Bellei NC, López E, Nogales Crespo KA, O’Ryan M, Villegas J. The Role of Serology Testing in the Context of Immunization Policies for COVID-19 in Latin American Countries. Viruses. 2021; 13(12):2391. https://doi.org/10.3390/v13122391

Chicago/Turabian Style

dos Santos Ferreira, Carlos E., Hector Gómez-Dantés, Nancy C. Junqueira Bellei, Eduardo López, Katya A. Nogales Crespo, Miguel O’Ryan, and Julieta Villegas. 2021. "The Role of Serology Testing in the Context of Immunization Policies for COVID-19 in Latin American Countries" Viruses 13, no. 12: 2391. https://doi.org/10.3390/v13122391

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