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Open AccessArticle

Surveillance for Adenoviruses in Bats in Italy

1
Dipartimento di Medicina Veterinaria, Università Aldo Moro di Bari, S.p per Casamassima km 3, 70010 Valenzano, Italy
2
Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna, Via Bianchi 9, 25124 Brescia, Italy
*
Author to whom correspondence should be addressed.
Viruses 2019, 11(6), 523; https://doi.org/10.3390/v11060523
Received: 7 May 2019 / Revised: 28 May 2019 / Accepted: 4 June 2019 / Published: 6 June 2019
(This article belongs to the Special Issue Viruses and Bats 2019)
Adenoviruses are important pathogens of humans and animals. Bats have been recognized as potential reservoirs of novel viruses, with some viruses being regarded as a possible zoonotic threat to humans. In this study, we report the detection and analysis of adenoviruses from different bat species in northern Italy. Upon sequence and phylogenetic analysis, based on a short diagnostic fragment of the highly-conserved DNA polymerase gene, we identified potential novel candidate adenovirus species, including an avian-like adenovirus strain. An adenovirus isolate was obtained in simian cell lines from the carcass of a Pipistrellus kuhlii, and the complete genome sequence was reconstructed using deep sequencing technologies. The virus displayed high nucleotide identity and virtually the same genome organization as the Pipistrellus pipistrellus strain PPV1, isolated in Germany in 2007. Gathering data on epidemiology and the genetic diversity of bat adenoviruses may be helpful to better understand their evolution in the mammalian and avian hosts. View Full-Text
Keywords: bat; adenovirus; mastadenovirus; aviadenovirus; sequence; NGS; Italy; phylogenetic analysis bat; adenovirus; mastadenovirus; aviadenovirus; sequence; NGS; Italy; phylogenetic analysis
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Diakoudi, G.; Lanave, G.; Moreno, A.; Chiapponi, C.; Sozzi, E.; Prosperi, A.; Larocca, V.; Losurdo, M.; Decaro, N.; Martella, V.; Lavazza, A.; Lelli, D. Surveillance for Adenoviruses in Bats in Italy. Viruses 2019, 11, 523.

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