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Viruses 2018, 10(7), 340; https://doi.org/10.3390/v10070340

Tick-Borne Flaviviruses and the Type I Interferon Response

1
Department of Clinical Microbiology, Virology, Umeå University, SE-90185 Umeå, Sweden
2
Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, SE-90187 Umeå, Sweden
3
Umeå Centre for Microbial Research (UCMR), Umeå University, SE-90187 Umeå, Sweden
Current address: Institut für Zytobiologie, Philipps-Universität Marburg, D-35032 Marburg, Germany.
*
Author to whom correspondence should be addressed.
Received: 29 May 2018 / Revised: 15 June 2018 / Accepted: 19 June 2018 / Published: 21 June 2018
(This article belongs to the Special Issue Biology and Treatment of Tick-Borne Viral Pathogens)
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Abstract

Flaviviruses are globally distributed pathogens causing millions of human infections every year. Flaviviruses are arthropod-borne viruses and are mainly transmitted by either ticks or mosquitoes. Mosquito-borne flaviviruses and their interactions with the innate immune response have been well-studied and reviewed extensively, thus this review will discuss tick-borne flaviviruses and their interactions with the host innate immune response. View Full-Text
Keywords: tick-borne flavivirus; innate immunity; interferon; tick-borne encephalitis virus; powassan virus; omsk hemorrhagic fever virus; kyasanur forest disease virus; louping ill virus; viperin tick-borne flavivirus; innate immunity; interferon; tick-borne encephalitis virus; powassan virus; omsk hemorrhagic fever virus; kyasanur forest disease virus; louping ill virus; viperin
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Lindqvist, R.; Upadhyay, A.; Överby, A.K. Tick-Borne Flaviviruses and the Type I Interferon Response. Viruses 2018, 10, 340.

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