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Revising the Subsystem Nurse’s A-Phase-Silicocarnotite within the System Ca3(PO4)2–Ca2SiO4

Instituto de Bioingenieria, Universidad Miguel Hernandez, Avda. Ferrocarril s/n. Elche, Alicante 03202, Spain
Departamento de Materiales, Óptica y Tecnologia Electrónica, Universidad Miguel Hernández, Avda. Universidad s/n, Elche (Alicante) 03202, Spain
Service of Orthopaedic at Arrixaca University Hospital, UCAM-Catholic University of Murcia, Murcia 30120, Spain
Author to whom correspondence should be addressed.
Academic Editor: Juergen Stampfl
Materials 2016, 9(5), 322;
Received: 18 January 2016 / Revised: 18 April 2016 / Accepted: 25 April 2016 / Published: 28 April 2016
(This article belongs to the Section Biomaterials)
PDF [2220 KB, uploaded 28 April 2016]


The subsystem Nurse’s A-phase-silicocarnotite within the system Ca3(PO4)2–Ca2SiO4 was conducted as a preliminary step toward obtaining new biomaterials with controlled microstructures. Phase composition of the resulting ceramics was studied by X-ray diffraction, differential thermal analysis, and scanning electron microscopy with attached wavelength dispersive spectroscopy. The results showed that the sub-system presents an invariant eutectoid point at 1366 ± 4 °C with a composition of 59.5 wt % Ca3(PO4)2 and 40.5 wt % Ca2SiO4, and typical eutectoid microstructure of lamellae morphology. These results are in disagreement with the previous reported data, which locate the invariant eutectoid point at 1250 ± 20 °C with a composition of 55 wt % Ca3(PO4)2 and 45 wt % Ca2SiO4. In addition, cell attachment testing showed that the new eutectoid material supported the mesenchymal stem cell adhesion and spreading, and the cells established close contact with the ceramic after 28 days of culture. These findings indicate that the new ceramic material with eutectoid microstructure of lamellae morphology possesses good bioactivity and biocompatibility and might be a promising bone implant material. View Full-Text
Keywords: phase diagram; bioceramic; biocompatibility; calcium phosphate silicate phase diagram; bioceramic; biocompatibility; calcium phosphate silicate

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Ros-Tárraga, P.; Mazón, P.; Meseguer-Olmo, L.; De Aza, P.N. Revising the Subsystem Nurse’s A-Phase-Silicocarnotite within the System Ca3(PO4)2–Ca2SiO4. Materials 2016, 9, 322.

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