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10.3390/ma9030149
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Article

Synthesis, Characterization and Cytotoxicity of Novel Multifunctional Fe3O4@SiO2@GdVO4:Dy3+ Core-Shell Nanocomposite as a Drug Carrier

by
Bo Li
,
Huitao Fan
*,
Qiang Zhao
and
Congcong Wang
College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China
*
Author to whom correspondence should be addressed.
Materials 2016, 9(3), 149; https://doi.org/10.3390/ma9030149
Submission received: 22 January 2016 / Revised: 22 February 2016 / Accepted: 24 February 2016 / Published: 2 March 2016
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Abstract

In this study, multifunctional Fe3O4@SiO2@GdVO4:Dy3+ nanocomposites were successfully synthesized via a two-step method. Their structure, luminescence and magnetic properties were characterized by X-ray diffraction (XRD), scanning electronic microscope (SEM), transmission electron microscopy (TEM), photoluminescence (PL) spectra and vibrating sample magnetometer (VSM). The results indicated that the as-prepared multifunctional composites displayed a well-defined core-shell structure. The composites show spherical morphology with a size distribution of around 360 nm. Additionally, the composites exhibit high saturation magnetization (20.40 emu/g) and excellent luminescence properties. The inner Fe3O4 cores and the outer GdVO4:Dy3+ layers endow the composites with good responsive magnetic properties and strong fluorescent properties, which endow the nanoparticles with great potential applications in drug delivery, magnetic resonance imaging, and marking and separating of cells in vitro.
Keywords: Fe3O4@SiO2@GdVO4:Dy3+; nanocomposites; core-shell structure; magnetic property; luminescence property Fe3O4@SiO2@GdVO4:Dy3+; nanocomposites; core-shell structure; magnetic property; luminescence property
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MDPI and ACS Style

Li, B.; Fan, H.; Zhao, Q.; Wang, C. Synthesis, Characterization and Cytotoxicity of Novel Multifunctional Fe3O4@SiO2@GdVO4:Dy3+ Core-Shell Nanocomposite as a Drug Carrier. Materials 2016, 9, 149. https://doi.org/10.3390/ma9030149

AMA Style

Li B, Fan H, Zhao Q, Wang C. Synthesis, Characterization and Cytotoxicity of Novel Multifunctional Fe3O4@SiO2@GdVO4:Dy3+ Core-Shell Nanocomposite as a Drug Carrier. Materials. 2016; 9(3):149. https://doi.org/10.3390/ma9030149

Chicago/Turabian Style

Li, Bo, Huitao Fan, Qiang Zhao, and Congcong Wang. 2016. "Synthesis, Characterization and Cytotoxicity of Novel Multifunctional Fe3O4@SiO2@GdVO4:Dy3+ Core-Shell Nanocomposite as a Drug Carrier" Materials 9, no. 3: 149. https://doi.org/10.3390/ma9030149

APA Style

Li, B., Fan, H., Zhao, Q., & Wang, C. (2016). Synthesis, Characterization and Cytotoxicity of Novel Multifunctional Fe3O4@SiO2@GdVO4:Dy3+ Core-Shell Nanocomposite as a Drug Carrier. Materials, 9(3), 149. https://doi.org/10.3390/ma9030149

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