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Volume 16
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10.3390/ma16062235
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Review

Polymeric and Composite Carriers of Protein and Non-Protein Biomolecules for Application in Bone Tissue Engineering

by
Dagmara Słota
1,*,
Karina Piętak
1,
Josef Jampilek
2,3 and
Agnieszka Sobczak-Kupiec
1
1
Department of Materials Science, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., 31-864 Krakow, Poland
2
Department of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Ilkovicova 6, 842 15 Bratislava, Slovakia
3
Department of Chemical Biology, Faculty of Science, Palacky University Olomouc, Slechtitelu 27, 783 71 Olomouc, Czech Republic
*
Author to whom correspondence should be addressed.
Materials 2023, 16(6), 2235; https://doi.org/10.3390/ma16062235
Submission received: 30 January 2023 / Revised: 2 March 2023 / Accepted: 8 March 2023 / Published: 10 March 2023
(This article belongs to the Special Issue Advanced Functional Materials for Biomedicinal Applications)
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Abstract

Conventional intake of drugs and active substances is most often based on oral intake of an appropriate dose to achieve the desired effect in the affected area or source of pain. In this case, controlling their distribution in the body is difficult, as the substance also reaches other tissues. This phenomenon results in the occurrence of side effects and the need to increase the concentration of the therapeutic substance to ensure it has the desired effect. The scientific field of tissue engineering proposes a solution to this problem, which creates the possibility of designing intelligent systems for delivering active substances precisely to the site of disease conversion. The following review discusses significant current research strategies as well as examples of polymeric and composite carriers for protein and non-protein biomolecules designed for bone tissue regeneration.
Keywords: biomolecules; hormones; flavonoids; lipids; growth factors; protein amino acids; osteopontin; bone sialoprotein; osteocalcin; osteonectin biomolecules; hormones; flavonoids; lipids; growth factors; protein amino acids; osteopontin; bone sialoprotein; osteocalcin; osteonectin
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MDPI and ACS Style

Słota, D.; Piętak, K.; Jampilek, J.; Sobczak-Kupiec, A. Polymeric and Composite Carriers of Protein and Non-Protein Biomolecules for Application in Bone Tissue Engineering. Materials 2023, 16, 2235. https://doi.org/10.3390/ma16062235

AMA Style

Słota D, Piętak K, Jampilek J, Sobczak-Kupiec A. Polymeric and Composite Carriers of Protein and Non-Protein Biomolecules for Application in Bone Tissue Engineering. Materials. 2023; 16(6):2235. https://doi.org/10.3390/ma16062235

Chicago/Turabian Style

Słota, Dagmara, Karina Piętak, Josef Jampilek, and Agnieszka Sobczak-Kupiec. 2023. "Polymeric and Composite Carriers of Protein and Non-Protein Biomolecules for Application in Bone Tissue Engineering" Materials 16, no. 6: 2235. https://doi.org/10.3390/ma16062235

APA Style

Słota, D., Piętak, K., Jampilek, J., & Sobczak-Kupiec, A. (2023). Polymeric and Composite Carriers of Protein and Non-Protein Biomolecules for Application in Bone Tissue Engineering. Materials, 16(6), 2235. https://doi.org/10.3390/ma16062235

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