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Article

Inactivating SARS-CoV-2 Using 275 nm UV-C LEDs through a Spherical Irradiation Box: Design, Characterization and Validation

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Department of Industrial Engineering, University of Padova, Via Gradenigo 6A, 35131 Padova, Italy
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Department of Information Engineering, University of Padova, Via Gradenigo 6B, 35131 Padova, Italy
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Department of Molecular Medicine, University of Padova, Via Gabelli 63, 35121 Padova, Italy
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LightCube SRL, Viale Navigazione Interna 51, 35129, Padova, Italy
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DBSV, University of Insubria, Via J.H. Dunant 3, 21100 Varese, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Valery V. Tuchin
Materials 2021, 14(9), 2315; https://doi.org/10.3390/ma14092315
Received: 24 February 2021 / Revised: 2 April 2021 / Accepted: 16 April 2021 / Published: 29 April 2021
(This article belongs to the Special Issue Advanced Materials for Biophotonics Applications)
We report on the design, characterization and validation of a spherical irradiation system for inactivating SARS-CoV-2, based on UV-C 275 nm LEDs. The system is designed to maximize irradiation intensity and uniformity and can be used for irradiating a volume of 18 L. To this aim: (i) several commercially available LEDs have been acquired and analyzed; (ii) a complete optical study has been carried out in order to optimize the efficacy of the system; (iii) the resulting prototype has been characterized optically and tested for the inactivation of SARS-CoV-2 for different exposure times, doses and surface types; (iv) the result achieved and the efficacy of the prototype have been compared with similar devices based on different technologies. Results indicate that a 99.9% inactivation can be reached after 1 min of treatment with a dose of 83.1 J/m2. View Full-Text
Keywords: SARS-CoV-2; COVID-19; LED; UVC; disinfection; inactivation; virucide SARS-CoV-2; COVID-19; LED; UVC; disinfection; inactivation; virucide
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MDPI and ACS Style

Trivellin, N.; Buffolo, M.; Onelia, F.; Pizzolato, A.; Barbato, M.; Orlandi, V.T.; Del Vecchio, C.; Dughiero, F.; Zanoni, E.; Meneghesso, G.; Crisanti, A.; Meneghini, M. Inactivating SARS-CoV-2 Using 275 nm UV-C LEDs through a Spherical Irradiation Box: Design, Characterization and Validation. Materials 2021, 14, 2315. https://doi.org/10.3390/ma14092315

AMA Style

Trivellin N, Buffolo M, Onelia F, Pizzolato A, Barbato M, Orlandi VT, Del Vecchio C, Dughiero F, Zanoni E, Meneghesso G, Crisanti A, Meneghini M. Inactivating SARS-CoV-2 Using 275 nm UV-C LEDs through a Spherical Irradiation Box: Design, Characterization and Validation. Materials. 2021; 14(9):2315. https://doi.org/10.3390/ma14092315

Chicago/Turabian Style

Trivellin, Nicola, Matteo Buffolo, Francesco Onelia, Alberto Pizzolato, Marco Barbato, Viviana Teresa Orlandi, Claudia Del Vecchio, Fabrizio Dughiero, Enrico Zanoni, Gaudenzio Meneghesso, Andrea Crisanti, and Matteo Meneghini. 2021. "Inactivating SARS-CoV-2 Using 275 nm UV-C LEDs through a Spherical Irradiation Box: Design, Characterization and Validation" Materials 14, no. 9: 2315. https://doi.org/10.3390/ma14092315

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