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Article

Red-Emitting Hybrid Based on Eu3+-dbm Complex Anchored on Silica Nanoparticles Surface by Carboxylic Acid for Biomarker Application

1
School of Technology and Sciences, São Paulo State University (Unesp), Presidente Prudente, SP 19060-900, Brazil
2
Institute of Biosciences, Humanities and Exact Sciences, São Paulo State University (Unesp), São José do Rio Preto, SP 15054-000, Brazil
3
Institute of Chemistry, São Paulo State University (Unesp), Araraquara, SP 14800-900, Brazil
*
Author to whom correspondence should be addressed.
Materials 2020, 13(23), 5494; https://doi.org/10.3390/ma13235494
Received: 3 October 2020 / Revised: 6 November 2020 / Accepted: 10 November 2020 / Published: 2 December 2020
(This article belongs to the Special Issue New Insights into Hybrid Biomaterials)
Luminescent organic-inorganic hybrids containing lanthanides (Ln3+) have been prominent for applications such as luminescent bio-probes in biological assays. In this sense, a luminescent hybrid based on dense silica (SiO2) nanospheres decorated with Eu3+ β–diketonate complexes using dibenzoylmethane (Hdbm) as a luminescent antenna was developed by using a hierarchical organization in four steps: (i) anchoring of 3-aminopropyltriethoxysilane (APTES) organosilane on the SiO2 surface, (ii) formation of a carboxylic acid ligand, (iii) coordination of Eu3+ to the carboxylate groups and (iv) coordination of dbm to Eu3+. The hybrid structure was elucidated through the correlation of thermogravimetry, silicon nuclear magnetic resonance and photoluminescence. Results indicate that the carboxylic acid-Eu3+-dbm hybrid was formed on the surface of the particles with no detectable changes on their size or shape after all the four steps (average size of 32 ± 7 nm). A surface charge of −27.8 mV was achieved for the hybrid, assuring a stable suspension in aqueous media. The Eu3+ complex provides intense red luminescence, characteristic of Eu3+5D07FJ electronic transitions, with an intrinsic emission quantum yield of 38%, even in an aqueous suspension. Therefore, the correlation of luminescence, structure, particle morphology and fluorescence microscopy images make the hybrid promising for application in bioimaging. View Full-Text
Keywords: luminescent material; functionalization; lanthanide; β–diketone; SiO2; bioimaging luminescent material; functionalization; lanthanide; β–diketone; SiO2; bioimaging
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MDPI and ACS Style

Santos, J.A.O.; Mutti, A.M.G.; Bispo-Jr, A.G.; Pires, A.M.; Lima, S.A.M. Red-Emitting Hybrid Based on Eu3+-dbm Complex Anchored on Silica Nanoparticles Surface by Carboxylic Acid for Biomarker Application. Materials 2020, 13, 5494. https://doi.org/10.3390/ma13235494

AMA Style

Santos JAO, Mutti AMG, Bispo-Jr AG, Pires AM, Lima SAM. Red-Emitting Hybrid Based on Eu3+-dbm Complex Anchored on Silica Nanoparticles Surface by Carboxylic Acid for Biomarker Application. Materials. 2020; 13(23):5494. https://doi.org/10.3390/ma13235494

Chicago/Turabian Style

Santos, João A.O., Alessandra M.G. Mutti, Airton G. Bispo-Jr, Ana M. Pires, and Sergio A.M. Lima. 2020. "Red-Emitting Hybrid Based on Eu3+-dbm Complex Anchored on Silica Nanoparticles Surface by Carboxylic Acid for Biomarker Application" Materials 13, no. 23: 5494. https://doi.org/10.3390/ma13235494

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