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Open AccessFeature PaperReview

Cellulose Composites with Graphene for Tissue Engineering Applications

1
Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, Gheorghe Polizu 1-7, 011061 Bucharest, Romania
2
Advanced Polymer Materials Group, Faculty of Applied Chemistry and Material Science, University Politehnica of Bucharest, Gheorghe Polizu 1-7, 011061 Bucharest, Romania
*
Author to whom correspondence should be addressed.
Materials 2020, 13(23), 5347; https://doi.org/10.3390/ma13235347
Received: 25 October 2020 / Revised: 24 November 2020 / Accepted: 24 November 2020 / Published: 25 November 2020
(This article belongs to the Special Issue Advanced Composite Biomaterials)
Tissue engineering is an interdisciplinary field that combines principles of engineering and life sciences to obtain biomaterials capable of maintaining, improving, or substituting the function of various tissues or even an entire organ. In virtue of its high availability, biocompatibility and versatility, cellulose was considered a promising platform for such applications. The combination of cellulose with graphene or graphene derivatives leads to the obtainment of superior composites in terms of cellular attachment, growth and proliferation, integration into host tissue, and stem cell differentiation toward specific lineages. The current review provides an up-to-date summary of the status of the field of cellulose composites with graphene for tissue engineering applications. The preparation methods and the biological performance of cellulose paper, bacterial cellulose, and cellulose derivatives-based composites with graphene, graphene oxide and reduced graphene oxide were mainly discussed. The importance of the cellulose-based matrix and the contribution of graphene and graphene derivatives fillers as well as several key applications of these hybrid materials, particularly for the development of multifunctional scaffolds for cell culture, bone and neural tissue regeneration were also highlighted. View Full-Text
Keywords: scaffolds; membranes; hydrogels; cellulose; tissue engineering scaffolds; membranes; hydrogels; cellulose; tissue engineering
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MDPI and ACS Style

Oprea, M.; Voicu, S.I. Cellulose Composites with Graphene for Tissue Engineering Applications. Materials 2020, 13, 5347. https://doi.org/10.3390/ma13235347

AMA Style

Oprea M, Voicu SI. Cellulose Composites with Graphene for Tissue Engineering Applications. Materials. 2020; 13(23):5347. https://doi.org/10.3390/ma13235347

Chicago/Turabian Style

Oprea, Madalina; Voicu, Stefan I. 2020. "Cellulose Composites with Graphene for Tissue Engineering Applications" Materials 13, no. 23: 5347. https://doi.org/10.3390/ma13235347

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