The Effect of Polyol Composition on the Structural and Magnetic Properties of Magnetite Nanoparticles for Magnetic Particle Hyperthermia
Abstract
:1. Introduction
2. Materials and Methods
2.1. Chemical Reagents
2.2. Materials Preparation
2.3. Characterization Techniques
3. Results
3.1. Structural Characterization
3.1.1. Transmission Electron Microscopy
3.1.2. XRD Measurements
3.1.3. Infra-Red Spectroscopy
3.1.4. Thermogravimetric Analysis
3.2. Magnetic Characterization and Hyperthermia
3.2.1. VSM Measurements
3.2.2. Magnetic Particle Hyperthermia
4. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Sample | Initial Components in Flask | Hot Injection (100 °C) | Final Temperature (°C) |
---|---|---|---|
TD1 | 5 mmol Fe(acac)3 300 mmol TrEG (40 mL) 5 mmol NaBH4 | - | 260 |
TD2 | 2.5 mmol Fe(acac)3 20 mmol PEG-1000 (20 g) | 2.5 mmol NaBH4 | 260 |
TD3 | 2.5 mmol PEG-8000 (20 g) | 2.5 mmol Fe(acac)3 2.5 mmol NaBH4 | 260 |
TD4 | 2.5 mmol Fe(acac)3 150 mmol TrEG (20 mL) 2.5 mmol N2H4·H2O | - | 260 |
Sample | Reactants | Temperature (°C) |
---|---|---|
SV5 | 1.5 mmol Fe(acac)3 75 mmol TrEG (10 mL) | 200 |
SV6 | 1.25 mmol Fe(acac)3 10 mmol PEG-1000 (10 g) | 200 |
SV7 | 1.25 mmol Fe(acac)3 1.25 mmol PEG-8000 (10 g) | 200 |
TD Samples | Nanoparticles’ Mean Size (nm) | Crystallites’ Mean Size (nm) | SV Samples | Crystallites’ Mean Size (nm) |
---|---|---|---|---|
TD1 (TrEG) | 12.8 (±3.3) | 11.8 | SV5 (TrEG) | 8.6 |
TD2 (PEG-1000) | 7.7 (±1.6) | 8.1 | SV6 (PEG-1000) | 13.7 |
TD3 (PEG-8000) | 4.1 (±1.0) | 4 | SV7 (PEG-8000) | 18.7 |
TD4 (TrEG/hydrazine) | 10.5 (±2.2) | 11.9 | - | - |
Sample | Ms (Am2/kgFe3O4) | Mr (Am2/kgFe3O4) | Mr/Ms (%) | Hc (mT) | Mean Size (nm) by TEM |
---|---|---|---|---|---|
TD1 | 73.7 | 34.2 | 46.3 | 17.8 | 12.8 |
TD2 | 40.2 | 11.3 | 28.2 | 12.2 | 7.70 |
TD3 | 12.6 | 0.9 | 6.80 | 18.4 | 4.10 |
TD4 | 66.0 | 6.20 | 9.40 | 14.0 | 10.5 |
Sample | Ms (Am2/kg) | Mr (Am2/kg) | Mr/Ms (%) | Hc (mT) | Crystallite Size (nm) by Scherrer’s Formula |
---|---|---|---|---|---|
SV5 | 64.1 | 16.2 | 25.3 | 17.6 | 8.60 |
SV6 | 53.3 | 16.1 | 30.2 | 17.8 | 13.7 |
SV7 | 46.3 | 11.0 | 23.8 | 18.5 | 18.7 |
Sample | Ms (Am2/kg) | Precursor mol/ Surfactant mol | Sample | Ms (Am2/kg) | Precursor mol/Surfactant mol |
---|---|---|---|---|---|
TD1 | 65.6 | 5: 300 | SV5 | 64.1 | 1.25: 75 |
TD2 | 34 | 2.5: 20 | SV6 | 53.3 | 1.25: 10 |
TD3 | 10.3 | 2.5: 2.5 | SV7 | 46.3 | 1.25:1.25 |
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Kotoulas, A.; Dendrinou-Samara, C.; Angelakeris, M.; Kalogirou, O. The Effect of Polyol Composition on the Structural and Magnetic Properties of Magnetite Nanoparticles for Magnetic Particle Hyperthermia. Materials 2019, 12, 2663. https://doi.org/10.3390/ma12172663
Kotoulas A, Dendrinou-Samara C, Angelakeris M, Kalogirou O. The Effect of Polyol Composition on the Structural and Magnetic Properties of Magnetite Nanoparticles for Magnetic Particle Hyperthermia. Materials. 2019; 12(17):2663. https://doi.org/10.3390/ma12172663
Chicago/Turabian StyleKotoulas, Anastasios, Catherine Dendrinou-Samara, Mavroeidis Angelakeris, and Orestis Kalogirou. 2019. "The Effect of Polyol Composition on the Structural and Magnetic Properties of Magnetite Nanoparticles for Magnetic Particle Hyperthermia" Materials 12, no. 17: 2663. https://doi.org/10.3390/ma12172663