Next Article in Journal
Research on High Performance Milling of Engineering Ceramics from the Perspective of Cutting Variables Setting
Next Article in Special Issue
Effects on the Mechanical Properties of Nacre-Like Bio-Hybrid Membranes with Inter-Penetrating Petal Structure Based on Magadiite
Previous Article in Journal
The Methacrylate Adhesive to Double-Lap Shear Joints Made of High-Strength Steel—Experimental Study
Previous Article in Special Issue
Adsorption Analyses of Phenol from Aqueous Solutions Using Magadiite Modified with Organo-Functional Groups: Kinetic and Equilibrium Studies
Open AccessReview

Immobilized Enzymes in Biosensor Applications

1
BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahangno, Yuseong-Gu, Daejeon 34141, Korea
2
Department of Nanobiotechnology, KRIBB School of Biotechnology, Korea University of Science and Technology (UST), 217 Gajeongno, Yuseong-Gu, Daejeon 34113, Korea
3
Department of Biochemistry, College of Natural Sciences, Chungnam National University, 99 Daehangno, Yuseong-Gu, Daejeon 34134, Korea
4
Department of Biology, College of Arts & Sciences, Tuskegee University, Tuskegee, AL 36830, USA
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Materials 2019, 12(1), 121; https://doi.org/10.3390/ma12010121
Received: 22 November 2018 / Revised: 15 December 2018 / Accepted: 24 December 2018 / Published: 2 January 2019
(This article belongs to the Special Issue Polymeric Nanocomposites for Flexible Sensor)
Enzyme-based biosensing devices have been extensively developed over the last few decades, and have proven to be innovative techniques in the qualitative and quantitative analysis of a variety of target substrates over a wide range of applications. Distinct advantages that enzyme-based biosensors provide, such as high sensitivity and specificity, portability, cost-effectiveness, and the possibilities for miniaturization and point-of-care diagnostic testing make them more and more attractive for research focused on clinical analysis, food safety control, or disease monitoring purposes. Therefore, this review article investigates the operating principle of enzymatic biosensors utilizing electrochemical, optical, thermistor, and piezoelectric measurement techniques and their applications in the literature, as well as approaches in improving the use of enzymes for biosensors. View Full-Text
Keywords: enzyme; immobilization; biosensor; immobilized enzyme; enzyme modification enzyme; immobilization; biosensor; immobilized enzyme; enzyme modification
Show Figures

Figure 1

MDPI and ACS Style

Nguyen, H.H.; Lee, S.H.; Lee, U.J.; Fermin, C.D.; Kim, M. Immobilized Enzymes in Biosensor Applications. Materials 2019, 12, 121.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop