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Materials 2018, 11(9), 1733;

Biomimetic Mineralizing Agents Recover the Micro Tensile Bond Strength of Demineralized Dentin

Department of Pediatric Dentistry, Piracicaba Dental School, State University of Campinas, Piracicaba 13414-903; Brazil
Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, Piracicaba 13414-903, Brazil
Division of Oral Biology, School of Dentistry, Faculty of Medicine & Health, University of Leeds, Leeds LS9 7TF, UK
Departments of Pediatric Dentistry and Restorative Dentistry, Piracicaba Dental School, University of Campinas, Piracicaba 13414-903, Brazil
Author to whom correspondence should be addressed.
Received: 10 July 2018 / Revised: 7 September 2018 / Accepted: 11 September 2018 / Published: 14 September 2018
(This article belongs to the Special Issue Bioactive and Therapeutic Dental Materials)
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Biomimetic remineralization is an approach that mimics natural biomineralization, and improves adhesive procedures. The aim of this paper was to investigate the influence of Dentin Caries-like Lesions (DCLL)-Producing Model on microtensile bond strength (μTBS) of etch and rinse adhesive systems and investigate the effect of remineralizing agents such as Sodium Fluoride (NaF), MI Paste™ (MP) and Curodont™ Repair (CR) on caries-affected dentin (n = 6). Nine groups were established: (1) Sound dentin; (2) Demineralized dentin/Chemical DCLL: (3) Demineralized dentin/Biological DCLL; (4) Chemical/DCLL + NaF; (5) Chemical/DCLL + MP; (6) Chemical/DCLL + CR; (7) Biological/DCLL + NaF; (8) Biological/DCLL + MP; (9) Biological/DCLL + CR. Then all dentin blocks were subjected to a bonding procedure with Adper™ Single Bond 2 adhesive system/Filtek Z350XT 4 mm high block, following this they were immersed in deionized water/24 h and then sectioned with ≅1 mm2 beams. The μTBS test was conducted at 1 mm/min/500 N loading. Failure sites were evaluated by SEM (scanning electron microscopy (150×). μTBS data were submitted to factorial ANOVA and Tukey’s test (p < 0.05). The highest values were found when demineralized dentin was treated with MP and CR, regardless caries lesion depth (p < 0.05). There was a predominance of adhesive/mixed in the present study. It was concluded that the use of the artificial dentin caries production models produces differences in the μTBS. Additionally MP and CR remineralizing agents could enhance adhesive procedures even at different models of caries lesion. View Full-Text
Keywords: dentin; desmineralization; microtensile bond strength dentin; desmineralization; microtensile bond strength

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Barbosa-Martins, L.F.; Sousa, J.P.; Alves, L.A.; Davies, R.P.W.; Puppin-Rontanti, R.M. Biomimetic Mineralizing Agents Recover the Micro Tensile Bond Strength of Demineralized Dentin. Materials 2018, 11, 1733.

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