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Freeform Perfusable Microfluidics Embedded in Hydrogel Matrices

IRNAS—Institute for development of advanced applied systems, Valvasorjeva 42, 2000 Maribor, Slovenia
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Materials 2018, 11(12), 2529; https://doi.org/10.3390/ma11122529
Received: 2 November 2018 / Revised: 8 December 2018 / Accepted: 10 December 2018 / Published: 12 December 2018
We report a modification of the freeform reversible embedding of suspended hydrogels (FRESH) 3D printing method for the fabrication of freeform perfusable microfluidics inside a hydrogel matrix. Xanthan gum is deposited into a CaCl2 infused gelatine slurry to form filaments, which are consequently rinsed to produce hollow channels. This provides a simple method for rapid prototyping of microfluidic devices based on biopolymers and potentially a new approach to the construction of vascular grafts for tissue engineering. View Full-Text
Keywords: freeform; hydrogel; gelatine; microfluidics; FRESH; bioprinting; vascularization freeform; hydrogel; gelatine; microfluidics; FRESH; bioprinting; vascularization
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Štumberger, G.; Vihar, B. Freeform Perfusable Microfluidics Embedded in Hydrogel Matrices. Materials 2018, 11, 2529.

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