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Article

Modification of the Ceramic Implant Surfaces from Zirconia by the Magnetron Sputtering of Different Calcium Phosphate Targets: A Comparative Study

by
Anna I. Kozelskaya
1,
Evgeny N. Bolbasov
1,
Alexey S. Golovkin
2,
Alexander I. Mishanin
2,
Alice N. Viknianshchuk
2,
Evgeny V. Shesterikov
1,3,
Andrey Ashrafov
1,
Vadim A. Novikov
4,
Alexander Y. Fedotkin
1,
Igor A. Khlusov
5,6,7 and
Sergey I. Tverdokhlebov
1,*
1
Laboratory for Plasma Hybrid Systems, The Weinberg Research Center, School of Nuclear Science & Engineering, Tomsk Polytechnic University, 634050 Tomsk, Russia
2
Institution of molecular biology and genetics, Almazov National Medical Research Centre, 197341 Saint Petersburg, Russia
3
Laboratory of Lidar Methods, V.E. Zuev Institute of Atmospheric Optics SB RAS, 634055 Tomsk, Russia
4
Faculty of Physics, Department of Semiconductor Physics, Tomsk State University, 634050 Tomsk, Russia
5
Research School of Chemistry & Applied Biomedical Sciences, Tomsk Polytechnic University, 634050 Tomsk, Russia
6
Department of Morphology and General Pathology, Siberian State Medical University, 634050 Tomsk, Russia
7
Institute of Living Systems, Immanuel Kant Baltic Federal University, 236041 Kaliningrad, Russia
*
Author to whom correspondence should be addressed.
Materials 2018, 11(10), 1949; https://doi.org/10.3390/ma11101949
Submission received: 19 September 2018 / Revised: 6 October 2018 / Accepted: 8 October 2018 / Published: 11 October 2018
(This article belongs to the Special Issue Bioceramics: Bioinert, Bioactive, and Coatings)
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Abstract

In this study, thin calcium phosphate (Ca-P) coatings were deposited on zirconia substrates by radiofrequency (RF) magnetron sputtering using different calcium phosphate targets (calcium phosphate tribasic (CPT), hydroxyapatite (HA), calcium phosphate monobasic, calcium phosphate dibasic dehydrate (DCPD) and calcium pyrophosphate (CPP) powders). The sputtering of calcium phosphate monobasic and DCPD powders was carried out without an inert gas in the self-sustaining plasma mode. The physico-chemical, mechanical and biological properties of the coatings were investigated. Cell adhesion on the coatings was examined using mesenchymal stem cells (MSCs). The CPT coating exhibited the best cell adherence among all the samples, including the uncoated zirconia substrate. The cells were spread uniformly over the surfaces of all samples.
Keywords: ZrO2; RF magnetron sputtering; surfaces; biomedical applications ZrO2; RF magnetron sputtering; surfaces; biomedical applications
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MDPI and ACS Style

Kozelskaya, A.I.; Bolbasov, E.N.; Golovkin, A.S.; Mishanin, A.I.; Viknianshchuk, A.N.; Shesterikov, E.V.; Ashrafov, A.; Novikov, V.A.; Fedotkin, A.Y.; Khlusov, I.A.; et al. Modification of the Ceramic Implant Surfaces from Zirconia by the Magnetron Sputtering of Different Calcium Phosphate Targets: A Comparative Study. Materials 2018, 11, 1949. https://doi.org/10.3390/ma11101949

AMA Style

Kozelskaya AI, Bolbasov EN, Golovkin AS, Mishanin AI, Viknianshchuk AN, Shesterikov EV, Ashrafov A, Novikov VA, Fedotkin AY, Khlusov IA, et al. Modification of the Ceramic Implant Surfaces from Zirconia by the Magnetron Sputtering of Different Calcium Phosphate Targets: A Comparative Study. Materials. 2018; 11(10):1949. https://doi.org/10.3390/ma11101949

Chicago/Turabian Style

Kozelskaya, Anna I., Evgeny N. Bolbasov, Alexey S. Golovkin, Alexander I. Mishanin, Alice N. Viknianshchuk, Evgeny V. Shesterikov, Andrey Ashrafov, Vadim A. Novikov, Alexander Y. Fedotkin, Igor A. Khlusov, and et al. 2018. "Modification of the Ceramic Implant Surfaces from Zirconia by the Magnetron Sputtering of Different Calcium Phosphate Targets: A Comparative Study" Materials 11, no. 10: 1949. https://doi.org/10.3390/ma11101949

APA Style

Kozelskaya, A. I., Bolbasov, E. N., Golovkin, A. S., Mishanin, A. I., Viknianshchuk, A. N., Shesterikov, E. V., Ashrafov, A., Novikov, V. A., Fedotkin, A. Y., Khlusov, I. A., & Tverdokhlebov, S. I. (2018). Modification of the Ceramic Implant Surfaces from Zirconia by the Magnetron Sputtering of Different Calcium Phosphate Targets: A Comparative Study. Materials, 11(10), 1949. https://doi.org/10.3390/ma11101949

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