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Materials 2018, 11(10), 1949;

Modification of the Ceramic Implant Surfaces from Zirconia by the Magnetron Sputtering of Different Calcium Phosphate Targets: A Comparative Study

Laboratory for Plasma Hybrid Systems, The Weinberg Research Center, School of Nuclear Science & Engineering, Tomsk Polytechnic University, 634050 Tomsk, Russia
Institution of molecular biology and genetics, Almazov National Medical Research Centre, 197341 Saint Petersburg, Russia
Laboratory of Lidar Methods, V.E. Zuev Institute of Atmospheric Optics SB RAS, 634055 Tomsk, Russia
Faculty of Physics, Department of Semiconductor Physics, Tomsk State University, 634050 Tomsk, Russia
Research School of Chemistry & Applied Biomedical Sciences, Tomsk Polytechnic University, 634050 Tomsk, Russia
Department of Morphology and General Pathology, Siberian State Medical University, 634050 Tomsk, Russia
Institute of Living Systems, Immanuel Kant Baltic Federal University, 236041 Kaliningrad, Russia
Author to whom correspondence should be addressed.
Received: 19 September 2018 / Revised: 6 October 2018 / Accepted: 8 October 2018 / Published: 11 October 2018
(This article belongs to the Special Issue Bioceramics: Bioinert, Bioactive, and Coatings)
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In this study, thin calcium phosphate (Ca-P) coatings were deposited on zirconia substrates by radiofrequency (RF) magnetron sputtering using different calcium phosphate targets (calcium phosphate tribasic (CPT), hydroxyapatite (HA), calcium phosphate monobasic, calcium phosphate dibasic dehydrate (DCPD) and calcium pyrophosphate (CPP) powders). The sputtering of calcium phosphate monobasic and DCPD powders was carried out without an inert gas in the self-sustaining plasma mode. The physico-chemical, mechanical and biological properties of the coatings were investigated. Cell adhesion on the coatings was examined using mesenchymal stem cells (MSCs). The CPT coating exhibited the best cell adherence among all the samples, including the uncoated zirconia substrate. The cells were spread uniformly over the surfaces of all samples. View Full-Text
Keywords: ZrO2; RF magnetron sputtering; surfaces; biomedical applications ZrO2; RF magnetron sputtering; surfaces; biomedical applications

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Kozelskaya, A.I.; Bolbasov, E.N.; Golovkin, A.S.; Mishanin, A.I.; Viknianshchuk, A.N.; Shesterikov, E.V.; Ashrafov, A.; Novikov, V.A.; Fedotkin, A.Y.; Khlusov, I.A.; Tverdokhlebov, S.I. Modification of the Ceramic Implant Surfaces from Zirconia by the Magnetron Sputtering of Different Calcium Phosphate Targets: A Comparative Study. Materials 2018, 11, 1949.

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