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Surgical Treatment of Distal Cholangiocarcinoma

by 1 and 2,*
Department of Surgery, Kettering Health Dayton, Dayton, OH 45405, USA
Departments of Oncology and Surgery, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA
Author to whom correspondence should be addressed.
Curr. Oncol. 2022, 29(9), 6674-6687;
Received: 29 July 2022 / Revised: 5 September 2022 / Accepted: 8 September 2022 / Published: 17 September 2022
(This article belongs to the Special Issue Therapeutic Strategies in Cholangiocarcinoma)
Distal cholangiocarcinoma (dCCA) is a rare malignancy arising from the epithelial cells of the distal biliary tract and has a poor prognosis. dCCA is often clinically silent and patients commonly present with locally advanced and/or distant disease. For patients identified with early stage, resectable disease, surgical resection with negative margins remains the only curative treatment strategy available. However, despite appropriate treatment and diligent surveillance, risk of recurrence remains high with nearly 50% of patients experiencing recurrence at 5 years subsequent to surgical resection; therefore, it is prudent to continue to optimize neoadjuvant and adjuvant therapies in order to reduce the risk of recurrence and improve overall survival. In this review, we discuss the clinical presentation, workup and surgical treatment of dCCA. View Full-Text
Keywords: distal cholangiocarincoma; hepatobiliary; malignancy distal cholangiocarincoma; hepatobiliary; malignancy
MDPI and ACS Style

Gorji, L.; Beal, E.W. Surgical Treatment of Distal Cholangiocarcinoma. Curr. Oncol. 2022, 29, 6674-6687.

AMA Style

Gorji L, Beal EW. Surgical Treatment of Distal Cholangiocarcinoma. Current Oncology. 2022; 29(9):6674-6687.

Chicago/Turabian Style

Gorji, Leva, and Eliza W. Beal. 2022. "Surgical Treatment of Distal Cholangiocarcinoma" Current Oncology 29, no. 9: 6674-6687.

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