Next Article in Journal
The Down-Regulation of Circ_0059707 in Acute Myeloid Leukemia Promotes Cell Growth and Inhibits Apoptosis by Regulating miR-1287-5p
Previous Article in Journal
Efficacy and Safety of the Addition of Internal Mammary Irradiation to Standard Adjuvant Radiation in Early-Stage Breast Cancer: A Systematic Review and Meta-Analysis
 
 
Review

Surgical Treatment of Distal Cholangiocarcinoma

by 1 and 2,*
1
Department of Surgery, Kettering Health Dayton, Dayton, OH 45405, USA
2
Departments of Oncology and Surgery, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2022, 29(9), 6674-6687; https://doi.org/10.3390/curroncol29090524
Received: 29 July 2022 / Revised: 5 September 2022 / Accepted: 8 September 2022 / Published: 17 September 2022
(This article belongs to the Special Issue Therapeutic Strategies in Cholangiocarcinoma)
Distal cholangiocarcinoma (dCCA) is a rare malignancy arising from the epithelial cells of the distal biliary tract and has a poor prognosis. dCCA is often clinically silent and patients commonly present with locally advanced and/or distant disease. For patients identified with early stage, resectable disease, surgical resection with negative margins remains the only curative treatment strategy available. However, despite appropriate treatment and diligent surveillance, risk of recurrence remains high with nearly 50% of patients experiencing recurrence at 5 years subsequent to surgical resection; therefore, it is prudent to continue to optimize neoadjuvant and adjuvant therapies in order to reduce the risk of recurrence and improve overall survival. In this review, we discuss the clinical presentation, workup and surgical treatment of dCCA. View Full-Text
Keywords: distal cholangiocarincoma; hepatobiliary; malignancy distal cholangiocarincoma; hepatobiliary; malignancy
MDPI and ACS Style

Gorji, L.; Beal, E.W. Surgical Treatment of Distal Cholangiocarcinoma. Curr. Oncol. 2022, 29, 6674-6687. https://doi.org/10.3390/curroncol29090524

AMA Style

Gorji L, Beal EW. Surgical Treatment of Distal Cholangiocarcinoma. Current Oncology. 2022; 29(9):6674-6687. https://doi.org/10.3390/curroncol29090524

Chicago/Turabian Style

Gorji, Leva, and Eliza W. Beal. 2022. "Surgical Treatment of Distal Cholangiocarcinoma" Current Oncology 29, no. 9: 6674-6687. https://doi.org/10.3390/curroncol29090524

Find Other Styles

Article Access Map by Country/Region

1
Back to TopTop