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Systematic Review

Health-Related Quality of Life following Total Thyroidectomy and Lobectomy for Differentiated Thyroid Carcinoma: A Systematic Review

1
Faculty of Medicine, University of Montreal, Montreal, QC H3T 1J4, Canada
2
School of Communication Sciences and Disorders, McGill University, Montreal, QC H3A 0G4, Canada
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Faculty of Medicine, McGill University, Montreal, QC H3A 0G4, Canada
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Gerald Bronfman Department of Oncology, McGill University, Montreal, QC H3A 0G4, Canada
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Department of Otolaryngology-Head and Neck Surgery, McGill University Health Center, Montreal, QC H4A 3J1, Canada
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Lady-Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC H3T 1E2, Canada
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Segal Cancer Centre, Jewish General Hospital, Montreal, QC H3T 1E2, Canada
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Department of Otolaryngology-Head and Neck Surgery, Jewish General Hospital, Montreal, QC H3T 1E2, Canada
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2022, 29(7), 4386-4422; https://doi.org/10.3390/curroncol29070350
Received: 31 March 2022 / Revised: 12 June 2022 / Accepted: 17 June 2022 / Published: 21 June 2022
(This article belongs to the Special Issue Psychosocial Effects of Head and Neck Cancer)
Health-related quality of life (HrQoL) is a major concern for patients with differentiated thyroid carcinoma (DTC). We aimed to systematically review the literature comparing HrQol following total thyroidectomy (TT) and hemithyroidectomy (HT) in DTC patients. A systematic review of publications indexed in Medline, Embase, and EBM reviews—Cochrane Central Register of Controlled Trials, which evaluated HrQoL following thyroid surgery for DTC, was conducted. Of 2507 identified records, 25 fulfilled the inclusion criteria. Our results suggest that patients undergoing TT may suffer more impairment in physical and social HrQoL than patients undergoing HT. Psychological-related HrQoL and long-term global HrQoL are, however, equivalent in both groups, which highlights the multidimensional nature of HrQoL and the importance of a multitude of factors aside from treatment modalities and related morbidities, such as the experience of receiving a cancer diagnosis, the fear of cancer recurrence, and other psychosocial factors. Addressing postoperative HrQoL when discussing therapeutic options with patients is an integral part of patient-centered care and informed shared decision-making, and should be approached in a holistic manner, accounting for its physical, psychological, and social aspects. This review supplies evidence regarding HrQoL following thyroid surgery, which can be employed in such decisions. View Full-Text
Keywords: thyroid neoplasms; differentiated thyroid cancer; quality of life; thyroidectomy; lobectomy thyroid neoplasms; differentiated thyroid cancer; quality of life; thyroidectomy; lobectomy
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MDPI and ACS Style

Landry, V.; Siciliani, E.; Henry, M.; Payne, R.J. Health-Related Quality of Life following Total Thyroidectomy and Lobectomy for Differentiated Thyroid Carcinoma: A Systematic Review. Curr. Oncol. 2022, 29, 4386-4422. https://doi.org/10.3390/curroncol29070350

AMA Style

Landry V, Siciliani E, Henry M, Payne RJ. Health-Related Quality of Life following Total Thyroidectomy and Lobectomy for Differentiated Thyroid Carcinoma: A Systematic Review. Current Oncology. 2022; 29(7):4386-4422. https://doi.org/10.3390/curroncol29070350

Chicago/Turabian Style

Landry, Vivianne, Elizabeth Siciliani, Melissa Henry, and Richard J. Payne. 2022. "Health-Related Quality of Life following Total Thyroidectomy and Lobectomy for Differentiated Thyroid Carcinoma: A Systematic Review" Current Oncology 29, no. 7: 4386-4422. https://doi.org/10.3390/curroncol29070350

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